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A stewardship intervention program for safe medication management and use of antidiabetic drugs

A stewardship intervention program for safe medication management and use of antidiabetic drugs Rui-yi Zhao,1 Xiao-wen He,1 Yan-min Shan,1 Ling-ling Zhu,2 Quan Zhou3 1Clinical Nurse Specialist

Evolutionary annotation of conserved long non-coding RNAs in major mammalian species

Mammalian genomes contain tens of thousands of long non-coding RNAs (lncRNAs) that have been implicated in diverse biological processes. However, the lncRNA transcriptomes of most mammalian species have not been established, limiting the evolutionary annotation of these novel transcripts. Based on RNA sequencing data from six tissues of nine species, we built comprehensive lncRNA...

Cluster Synchronization of Impulsive Complex Networks with Stochastic Perturbations and Time-Varying Delays

: Yannick De Decker Copyright © 2013 Yi Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction

M2-polarized macrophages in keratocystic odontogenic tumor: relation to tumor angiogenesis

of Stomatology, Wuhan University, Wuhan, ChinaWen-Qun Zhong, Gang Chen, Wei Zhang, Xue-Peng Xiong, Yi Zhao, Bing Liu & Yi-Fang ZhaoDepartment of Oral and Maxillofacial Surgery, School and Hospital of ... • PubMed • Google ScholarSearch for Xue-Peng Xiong in:Nature Research journals • PubMed • Google ScholarSearch for Yi Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Bing Liu in:Nature

Transcriptome analysis of Brassica napus pod using RNA-Seq and identification of lipid-related candidate genes

Xiang-Yang Lou 0 Jian-Yi Zhao 1 0 Department of Biostatistics and Bioinformatics, Tulane University , 1440 Canal St., Suite 2001, New Orleans, LA 70112-2632 , USA 1 State Key Laboratory Breeding Base

Local administration of siRNA through Microneedle: Optimization, Bio-distribution, Tumor Suppression and Toxicity

work. AffiliationsDepartment of Obstetrics & Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaTao Tang, Yan Deng, Jiao Chen, Yi Zhao, Kwong ... in:Nature Research journals • PubMed • Google ScholarSearch for Jiao Chen in:Nature Research journals • PubMed • Google ScholarSearch for Yi Zhao in:Nature Research journals • PubMed • Google ScholarSearch

Knowledge-Based Approach to Assembly Sequence Planning for Wind-Driven Generator

Assembly sequence planning plays an essential role in the manufacturing industry. However, there still exist some challenges for the research of assembly planning, one of which is the weakness in effective description of assembly knowledge and information. In order to reduce the computational task, this paper presents a novel approach based on engineering assembly knowledge to...

Synchronizability of Small-World Networks Generated from a Two-Dimensional Kleinberg Model

© 2013 Yi Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

Association between non-alcoholic fatty liver disease and arterial stiffness in the non-obese, non-hypertensive, and non-diabetic young and middle-aged Chinese population

Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Compliance with ethics guidelines Xin-yan YU, Yi ZHAO, Xiao-xiao SONG, and Zhen-ya SONG declare that they have no conflict of

Evolution of Gene Regulation during Transcription and Translation

Understanding how gene regulation evolves is a key area in the current evolutionary field. Gene regulation occurs at various levels. Previous work on the evolution of gene regulation has largely focused on gene transcription. In this study, we used a recently developed ribosomal footprint profiling method to investigate how gene regulation evolves at both the transcription (mRNA...

Identification of miRNAs during mouse postnatal ovarian development and superovulation

Background MicroRNAs are small noncoding RNAs that play critical roles in regulation of gene expression in wide array of tissues including the ovary through sequence complementarity at post-transcriptional level. Tight regulation of multitude of genes involved in ovarian development and folliculogenesis could be regulated at transcription level by these miRNAs. Therefore, tissue...

Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations

Haiquan Chen in:Nature Research journals • PubMed • Google Scholar Search for Shijian Zhang in:Nature Research journals • PubMed • Google Scholar Search for Yi Zhao in:Nature Research journals • PubMed

An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors

Transcription factors (TFs) play key roles in both development and stress responses. By integrating into and rewiring original systems, novel TFs contribute significantly to the evolution of transcriptional regulatory networks. Here, we report a high-confidence transcriptional regulatory map covering 388 TFs from 47 families in Arabidopsis. Systematic analysis of this map...

Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice

Curcumin, a selective phosphorylase kinase inhibitor, is a naturally occurring phytochemical present in turmeric. Curcumin has been confirmed to have anti-inflammatory properties in addition to the ability to decrease the expression of pro-inflammatory cytokines in keratinocytes. The interleukin-23 (IL-23)/IL-17A cytokine axis plays a critical role in the pathogenesis of...

High-performance flexible Ag nanowire electrode with low-temperature atomic-layer-deposition fabrication of conductive-bridging ZnO film

As material for flexible transparent electrodes for organic photoelectric devices, the silver nanowires (AgNWs) have been widely studied. In this work, we propose a hybrid flexible anode with photopolymer substrate, which is composed of spin-coating-processed AgNW meshes and of zinc oxide (ZnO) prepared by low-temperature (60°C) atomic layer deposition. ZnO effectively fills in...

Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model

Background Epigenetic regulation has emerged to be the critical steps for tumorigenesis and metastasis. Multiple histone methyltransferase and demethylase have been implicated as tumor suppressors or oncogenes recently. But the key epigenomic events in cancer cell transformation still remain poorly understood. Methods A breast cancer transformation model was established via...

Single Impulsive Controller for Exponential Synchronization of Stochastic Lur'e Networks with Impulsive Disturbance

Sciences, Shenzhen University, Shenzhen 518060, China Received 8 January 2013; Accepted 22 April 2013 Academic Editor: Jinde Cao Copyright © 2013 Yi Zhao et al. This is an open access article

Accelerated green process of tetramethylpyrazine production from glucose and diammonium phosphate

Background 2,3,5,6-Tetramethylpyrazine (TMP) is a popular food flavour additive. This biologically active ingredient has additional potential dietotherapy functions, such as in cardiovascular and cerebrovascular health. Previous production methods from renewable materials suffer from low yields and efficiency which seriously hampers the scaling up of the laboratory processes...

PEComa of the uterus with coexistence of situs inversus totalis, a case report and literature review

PEComas are a group of very rare mesenchymal neoplasms, which express myogenic and melanocytic markers, such as HMB-45 and actin. Situs inversus totalis represents a complete left to right side transposition of the asymmetrical thoracic and abdominal organs and incorporates dextrocardia. The presence of uterus PEComa in the setting of situs inversus totalis is extremely rare...

NONCODE 2016: an informative and valuable data source of long non-coding RNAs

NONCODE (http://www.bioinfo.org/noncode/) is an interactive database that aims to present the most complete collection and annotation of non-coding RNAs, especially long non-coding RNAs (lncRNAs). The recently reduced cost of RNA sequencing has produced an explosion of newly identified data. Revolutionary third-generation sequencing methods have also contributed to more accurate...