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Ceftriaxone Treatment for Neuronal Deficits: A Histological and MEMRI Study in a Rat Model of Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) is characterized by neuronal deficits and α-synuclein inclusions in the brain. Ceftriaxone (CEF), a β-lactam antibiotic, has been suggested as a therapeutic agent in several neurodegenerative disorders for its abilities to counteract glutamate-mediated toxicity and to block α-synuclein polymerization. By using manganese-enhanced magnetic resonance...

Ceftriaxone Treatment for Neuronal Deficits: A Histological and MEMRI Study in a Rat Model of Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) is characterized by neuronal deficits and α-synuclein inclusions in the brain. Ceftriaxone (CEF), a β-lactam antibiotic, has been suggested as a therapeutic agent in several neurodegenerative disorders for its abilities to counteract glutamate-mediated toxicity and to block α-synuclein polymerization. By using manganese-enhanced magnetic resonance...

Ceftriaxone Treatment for Neuronal Deficits: A Histological and MEMRI Study in a Rat Model of Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) is characterized by neuronal deficits and α-synuclein inclusions in the brain. Ceftriaxone (CEF), a β-lactam antibiotic, has been suggested as a therapeutic agent in several neurodegenerative disorders for its abilities to counteract glutamate-mediated toxicity and to block α-synuclein polymerization. By using manganese-enhanced magnetic resonance...

Improved activity of β-cyclodextrin glycosyltransferase from Bacillus sp. N-227 via mutagenesis of the conserved residues

β-Cyclodextrin glycosyltransferase (β-CGTase) belongs to the α-amylase family of enzymes and converts starch to cyclic oligosaccharides called β-cyclodextrins (β-CD). The β-CGTase from alkalophilic Bacillus sp. N-227 was separately mutagenized to give three site-directed β-CGTase mutants, Y127F, R254F and D355R, that showed enhanced cyclization activity towards a starch substrate...

Correction: Induction of Connective Tissue Growth Factor Expression by Hypoxia in Human Lung Fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 Pathways

-Yun Chen Chien-Hua Li Yu-Tin Liu Bing-Chang Chen The α-tubulin displayed in the bottom panel of Fig 4C is incorrect. Please see the complete correct Fig 4 here. OPEN ACCESS - Copyright: © 2017 Cheng

The prospect of rising in rank is key to long-term stability in Tibetan macaque society

One of the most fundamental questions in behavioural biology is why societies can persist for a long period of time. While researchers in animal behaviour have been hindered by a lack of an aggregate measure (such as social mobility) to quantify the dynamics of animal societies, researchers in social sciences have been challenged by the complexity and diversity of human societies...

Baculovirus-Mediated miR-214 Knockdown Shifts Osteoporotic ASCs Differentiation and Improves Osteoporotic Bone Defects Repair

. AffiliationsDepartment of Chemical Engineering, National Tsing Hua University, Hsinchu, 300, TaiwanKuei-Chang Li, Mu-Nung Hsu, Shih-Chun Lo, Wan-Hua Li & Yu-Chen HuCenter for Tissue Engineering, Chang Gung Memorial ... Research journals • PubMed • Google Scholar Search for Wan-Hua Li in:Nature Research journals • PubMed • Google Scholar Search for Yu-Chen Hu in:Nature Research journals • PubMed • Google Scholar

Design and Implementation of Acoustic Sensing System for Online Early Fault Detection in Industrial Fans

experiments and wrote the manuscript based on his master’s thesis archived domestically in Chinese in Taiwan. Tien-Hua Li, Chih-Hui Su, Lung-Hsien Huang, and Chih-Hsiung Chang technically supported the project

Design and Implementation of Acoustic Sensing System for Online Early Fault Detection in Industrial Fans

experiments and wrote the manuscript based on his master’s thesis archived domestically in Chinese in Taiwan. Tien-Hua Li, Chih-Hui Su, Lung-Hsien Huang, and Chih-Hsiung Chang technically supported the project

Ecophysiological response of native and exotic salt marsh vegetation to waterlogging and salinity: Implications for the effects of sea-level rise

The ecophysiological characteristics of native Phragmites australis and exotic Spartina alterniflora grown under waterlogging and salinity were investigated to explore their adaptation potential to sea level rise. The seasonal course of phenotypic traits, photosynthetic activity and chlorophyll fluorescence parameters of P. australis did not change remarkably under shallow...

MiR-200c regulates tumor growth and chemosensitivity to cisplatin in osteosarcoma by targeting AKT2

to this work. AffiliationsDepartment of Orthopedic, Huaihe Hospital of Henan University, Baobei Road 8, 475000, Kaifeng, Henan, ChinaYang Liu, Shu-Tao Zhu, Xiao Wang, Jun Deng, Wei-Hua Li, Peng Zhang ... in:Nature Research journals • PubMed • Google Scholar Search for Jun Deng in:Nature Research journals • PubMed • Google Scholar Search for Wei-Hua Li in:Nature Research journals • PubMed • Google Scholar

Echinacoside Alleviates UVB Irradiation-Mediated Skin Damage via Inhibition of Oxidative Stress, DNA Damage, and Apoptosis

Medicine, Sichuan Academy of Chinese Medicine Sciences, Chengdu 610041, China Correspondence should be addressed to Hua Li; moc.nuyila@elimsauhil, Jianbo Wang; nc.ude.ummf@bjwsyy, and Aidong Wen; moc.621 ... Zhang helped in the analysis of data. Hua Li collected the data, provided constructive comments, and drafted the manuscript. Jianbo Wang and Aidong Wen conceived and supervised the study. Di Zhang

Echinacoside Alleviates UVB Irradiation-Mediated Skin Damage via Inhibition of Oxidative Stress, DNA Damage, and Apoptosis

Medicine, Sichuan Academy of Chinese Medicine Sciences, Chengdu 610041, China Correspondence should be addressed to Hua Li; moc.nuyila@elimsauhil, Jianbo Wang; nc.ude.ummf@bjwsyy, and Aidong Wen; moc.621 ... Zhang helped in the analysis of data. Hua Li collected the data, provided constructive comments, and drafted the manuscript. Jianbo Wang and Aidong Wen conceived and supervised the study. Di Zhang

Identification of Biomarkers for Predicting Lymph Node Metastasis of Stomach Cancer Using Clinical DNA Methylation Data

Background. Lymph node (LN) metastasis was an independent risk factor for stomach cancer recurrence, and the presence of LN metastasis has great influence on the overall survival of stomach cancer patients. Thus, accurate prediction of the presence of lymph node metastasis can provide guarantee of credible prognosis evaluation of stomach cancer patients. Recently, increasing...

An Observer-Based Controller with a LMI-Based Filter against Wind-Induced Motion for High-Rise Buildings

Correspondence should be addressed to Zuo-Hua Li; nc.ude.tih@auhouzil Received 23 December 2016; Revised 21 March 2017; Accepted 11 April 2017; Published 25 May 2017 Academic Editor: Jiming Xie Copyright

An Observer-Based Controller with a LMI-Based Filter against Wind-Induced Motion for High-Rise Buildings

Active mass damper (AMD) control system is proposed for high-rise buildings to resist a strong wind. However, negative influence of noise in sensors impedes the application of AMD systems in practice. To reduce the adverse influence of noise on AMD systems, a Kalman filter and a linear matrix inequality- (LMI-) based filter are designed. Firstly, a ten-year return period...

An Observer-Based Controller with a LMI-Based Filter against Wind-Induced Motion for High-Rise Buildings

Correspondence should be addressed to Zuo-Hua Li; nc.ude.tih@auhouzil Received 23 December 2016; Revised 21 March 2017; Accepted 11 April 2017; Published 25 May 2017 Academic Editor: Jiming Xie Copyright

Red blood cell distribution width and carotid intima-media thickness in patients with metabolic syndrome

Background To evaluate the relationship between red blood cell distribution width (RDW) and carotid intima-media thickness (CIMT) in metabolic syndrome (MetS) patients. Methods In this study, we analyzed 803 patients with MetS who underwent carotid ultrasonography examination at Henan Province Hospital of Traditional Chinese Medicine from October 2014 to September 2015...

Utility of quantitative contrast-enhanced ultrasound for the prediction of extracapsular extension in papillary thyroid carcinoma

-Hua Li OPEN Published: xx xx xxxx The aim of this study was to find an accurate method for the detection of extracapsular extension (ECE) in papillary thyroid carcinoma (PTC). A total of 102 patients