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Multiferroic Phases and Transitions in Ferroelectric Lead Titanate Nanodots

Discovery of novel phases and their associated transitions in low-dimensional nanoscale systems is of central interest as the origin of emergent phenomena and new device paradigms. Although typical ferroelectrics such as PbTiO3 exhibit diverse phase transition sequences, the conventional incompatible mechanisms of ferroelectricity and magnetism keep them as simply nonmagnetic...

Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction

Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction Canhua Jiang,1 Shufang Jin,1 Zhisheng Jiang,1 Jie Wang2 1Department of Oral and Maxillofacial Surgery, Xiangya Hospital, 2Department of Immunology, Xiangya School of Medicine, Central South University, Changsha...

Turns with multiple and single head cast mediate Drosophila larval light avoidance

. Funding acquisition: Nenggan Zheng, Zhefeng Gong. Investigation: Weiqiao Zhao, Caixia Gong, Jie Wang, Peipei Zhou. Methodology: Weiqiao Zhao, Nenggan Zheng, Zhefeng Gong. Project administration: Nenggan ... Zhao, Caixia Gong, Jie Wang, Peipei Zhou. Visualization: Nenggan Zheng, Zhefeng Gong. Writing ± original draft: Nenggan Zheng, Zhefeng Gong. Writing ± review & editing: Nenggan Zheng, Zhefeng Gong. 11

Starvation during pregnancy impairs fetal oogenesis and folliculogenesis in offspring in the mouse

Although it is becoming increasingly evident that maternal starvation during pregnancy can have permanent effects on a range of physiological processes in the offspring, scant information is available about the consequence of such condition for oogenesis and hence for lifetime reproductive success of progeny in mammals. In the present study, we address this topic by starving...

SHP2 associates with nuclear localization of STAT3: significance in progression and prognosis of colorectal cancer

Tyrosine phosphatase SHP2, encoded by PTPN11, has been implicated in many physiologic and pathologic processes in neoplastic progression. However, controversies are emerging from many studies, indicating SHP2 has a dual role in different types of tumors. We aimed to explore the role of SHP2 in progression and prognosis of colorectal cancer (CRC). SHP2 inhibited CRC cell...

The relationship between human leukocyte antigen-DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population

Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationship of HLA-DP rs9277535 and HLA-DQ rs7453920 with the outcomes of HCV infection. The rs9277535 and rs7453920 were genotyped in 370 subjects with chronic HCV infection, 194...

Identification and characterization of interferon signaling-related microRNAs in occult hepatitis B virus infection

Background Occult hepatitis B virus infection (OBI) is an important risk factor of liver cirrhosis and hepatocellular carcinoma. Type 1 interferon (IFN) signaling-related miRNAs were significantly associated with hepatitis B virus (HBV) infection. However, the characteristics of serum IFN signaling-related miRNAs in OBI remain unclear. Therefore, this study aimed to analyze the...

The relationship between human leukocyte antigen-DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population

Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationship of HLA-DP rs9277535 and HLA-DQ rs7453920 with the outcomes of HCV infection. The rs9277535 and rs7453920 were genotyped in 370 subjects with chronic HCV infection, 194...

Production of bioactive liver-targeting interferon Mu-IFN-CSP by soluble prokaryotic expression

A novel liver-targeting interferon (IFN-CSP) was successfully over-expressed in our previous work. The in vitro and in vivo investigation revealed that IFN-CSP has significant anti-hepatitis B virus (HBV) effect and liver-targeting capacity. However, due to the IFN-CSP tends to form inclusion bodies in recombinant Escherichia coli (E. coli), efficient production of the soluble...

A note on fractional integral operators on Herz spaces with variable exponent

In this note, we prove that the fractional integral operators from Herz spaces with variable exponent K ˙ p ( ⋅ ) , q α to Lipschitz-type spaces are bounded provided p ( ⋅ ) is locally log-Hölder continuous and log-Hölder continuous at infinity. MSC: 42B20, 46E30.

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15224, USA These authors contributed equally: Jie Wang, Cristina Zibetti. AffiliationsDepartment of Ophthalmology, Johns Hopkins ... of Medicine, Baltimore, MD, 21205, USASeth BlackshawInstitute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USASeth Blackshaw AuthorsSearch for Jie Wang

Sequencing of complete mitochondrial genomes confirms synonymization of Hyalomma asiaticum asiaticum and kozlovi, and advances phylogenetic hypotheses for the Ixodidae

Chen, Chuang-Fu Chen. Resources: Zhi-Qiang Liu, Nuer Kuermanali, Chen-Feng Shen. Software: Yan-Feng Liu, Jie Wang. Supervision: Zhuang-Zhi Zhang, Chuang-Fu Chen. Validation: Zhi-Qiang Liu, Jun-Wei ... Wang. Visualization: Hui-Ling Guo, Jie Wang. 10 / 14 Writing ± original draft: Zhi-Qiang Liu, Yan-Feng Liu, Nuer Kuermanali, Deng-Feng Wang, Yuan-Zhi Wang. Writing ± review & editing: Zhi-Qiang Liu

Associations between fatty liver index and asymptomatic intracranial vertebrobasilar stenosis in Chinese population

Huai'an Third hospital and Huai'an Fourth hospital for Author Contributions Data curation: Jing Qiu, Zhiwei Zhou, Jie Wang, Yiying Wang. Formal analysis: Jing Qiu, Zhiwei Zhou. Funding acquisition: Chen ... Dong. Investigation: Jing Qiu, Zhiwei Zhou, Jie Wang, Yiying Wang, Chunxing Liu, Xingxiang Liu, Yunfang Xu, Lugang Yu, Hui Zhou, Jie Lin. Methodology: Zhirong Guo, Chen Dong. Project administration

A promising magnetic resonance stem cell tracer based on natural biomaterials in a biological system: manganese (II) chelated to melanin nanoparticles

A promising magnetic resonance stem cell tracer based on natural biomaterials in a biological system: manganese (II) chelated to melanin nanoparticles Shi-Jie Liu,1,2,* Ling-Jie Wang,1,* Ying Qiao,1

The jamming mechanism of sand control screen for the montmorillonite inflation with the water

In the process of well completion with mechanical screen to control sand, once the water content of the reservoir increased, the montmorillonite in clay minerals would swell which combined with formation sand has an obvious effect on the plugging of screen pipe in production string. According to the prediction of water production of reservoir, shale expansion instrument was used...

Sliding of coherent twin boundaries

Jiaotong University, Xi’an, 710049, ChinaZhang-Jie Wang, Yao Li, Long-Chao Huang, Ming Dao, Ju Li, Evan Ma & Zhi-Wei ShanDepartment of Materials Science and Engineering, Johns Hopkins University, Baltimore ... , 02139, USAJu LiNanyang Technological University, 50 Nanyang Avenue, Main Campus, Singapore, 639798, SingaporeSubra Suresh AuthorsSearch for Zhang-Jie Wang in:Nature Research journals • PubMed • Google

Integrated omics dissection of proteome dynamics during cardiac remodeling

Transcript abundance and protein abundance show modest correlation in many biological models, but how this impacts disease signature discovery in omics experiments is rarely explored. Here we report an integrated omics approach, incorporating measurements of transcript abundance, protein abundance, and protein turnover to map the landscape of proteome remodeling in a mouse model...

TRAF6 is a novel NS3-interacting protein that inhibits classical swine fever virus replication

Classical swine fever virus (CSFV) non-structural protein 3 (NS3) is a multifunctional non-structural protein that plays a major role in viral replication. However, how exactly NS3 exerts these functions remains unknown. Here, we identified tumour necrosis factor receptor-associated factor 6 (TRAF6) as a novel NS3-interacting protein via yeast two-hybrid analysis, co...

Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells

Melanoma Research Center, The Wistar Institute, Philadelphia, PA, 19104, USAMeenhard Herlyn & Ying-Jie Wang AuthorsSearch for Yanwen Zhou in:Nature Research journals • PubMed • Google Scholar Search for ... Research journals • PubMed • Google Scholar Search for Ying-Jie Wang in:Nature Research journals • PubMed • Google Scholar Conflict of interest The authors declare that they have no conflict of interest

CTCF-Mediated and Pax6-Associated Gene Expression in Corneal Epithelial Cell-Specific Differentiation

Background The purpose of the study is to elicit the epigenetic mechanism involving CCCTC binding factor (CTCF)-mediated chromatin remodeling that regulates PAX6 gene interaction with differentiation-associated genes to control corneal epithelial differentiation. Methods Cell cycle progression and specific keratin expressions were measured to monitor changes of differentiation...