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Distribution of CYP2C19 polymorphisms in Mongolian and Han nationals and the choice of specific antiplatelet drugs

Background Individualized medication reviews may improve our understanding of the distribution of CYP2C19 polymorphisms in ethnic populations. Objective To evaluate differences in CYP2C19 gene polymorphisms between Mongolian and Han nationals and determine the effect of adjustments of antiplatelet treatments according to the genetic profile in patients undergoing percutaneous...

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

GTPase-activating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases. Several GAPs and GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamatergic neurons and regulate the activity of glutamate receptors. However, it is not known how synaptic GAP and GEF proteins are...

Clinical Efficacy and Safety of Aidi Injection Plus Docetaxel-Based Chemotherapy in Advanced Nonsmall Cell Lung Cancer: A Meta-Analysis of 36 Randomized Controlled Trials

Wang,1,2 Lianhong Li,3 Xuemei Tang,3 Nana Li,2 Jing Li,4 Ling Chen,1,2 Qihai Gong,5 Fushan Tang,5 Jihong Feng,6 and Xiaofei Li7 1Evidence-Based Medicine Center, MOE Virtual Research Center of Evidence ... information. 2.7. Statistical Analysis Meta-analysis was implemented by two reviewers (Chengqiong Wang and Jing Li) using Review Manager 5.3 (The Cochrane Collaboration, Oxford, UK). The relative risk (RR) and

Clinical Efficacy and Safety of Aidi Injection Plus Docetaxel-Based Chemotherapy in Advanced Nonsmall Cell Lung Cancer: A Meta-Analysis of 36 Randomized Controlled Trials

. 2.7. Statistical Analysis. Meta-analysis was implemented by two reviewers (Chengqiong Wang and Jing Li) using Review Manager 5.3 (The Cochrane Collaboration, Oxford, UK). The relative risk (RR) and 95 ... Wang and Jing Li performed the statistical analysis. Chengqiong Wang, Zheng Xiao, Ling Chen, Qihai Gong, Fushan Tang, Jihong Feng, and Xiaofei Li wrote, reviewed, and/or revised the manuscript:. Zheng

Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4

Macau, Macau, People’s Republic of ChinaLi Wang, Jing-jing Li, Peipei Li, Zhiqiang Zhao & Li-jun DiDepartment of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, 230032, ChinaLi-yu Guo ...  & Haisheng Zhou AuthorsSearch for Li Wang in:Nature Research journals • PubMed • Google Scholar Search for Jing-jing Li in:Nature Research journals • PubMed • Google Scholar Search for Li-yu Guo in:Nature

Up-regulation of microRNA-203 in influenza A virus infection inhibits viral replication by targeting DR1

MicroRNAs (miRNAs) are small noncoding RNA molecules that play important roles in various biological processes. Much evidence shows that miRNAs are closely associated with numerous virus infections; however, involvement of cellular miRNAs in influenza A virus (IAV) infection is unclear. Here, we found that expression of miR-203 was up-regulated markedly via two different...

Genetic diversity and structure of core collection of winter mushroom (Flammulina velutipes) developed by genomic SSR markers

Background A core collection is a subset of an entire collection that represents as much of the genetic diversity of the entire collection as possible. The establishment of a core collection for crops is practical for efficient management and use of germplasm. However, the establishment of a core collection of mushrooms is still in its infancy, and no established core collection...

The association of telomere attrition with first-onset stroke in Southern Chinese: a case-control study and meta-analysis

The relationship between telomere length and stroke was inconsistent mostly due to different pathogenesis of subtypes, environment and genetics. We aimed to assess whether leukocyte telomere contributes to stroke in Southern Chinese by investigating a case-control study comprising 543 cases (224 atherothrombotic stroke, 94 hemorrhagic stroke and 225 lacunar infraction) and 616...

Analysis of the genotype-phenotype correlation in patients with phenylketonuria in mainland China

University (grant ID: IRT0935). Author information Author notes Nana Li, Chunhua He and Jing Li contributed equally to this work. AffiliationsNational Center for Birth Defect Monitoring, West China Second ... journals • PubMed • Google Scholar Search for Jing Li in:Nature Research journals • PubMed • Google Scholar Search for Jing Tao in:Nature Research journals • PubMed • Google Scholar Search for Zhen Liu

Correction to: Simultaneous Modification of Alumina and MgO·Al2O3 Inclusions by Calcium Treatment During Electroslag Remelting of Stainless Tool Steel

In Table III, the correct value of first-order interaction parameter of Cr on S should be −0.0105, rather than 0.0105. It should be stressed that the thermodynamic calculation associated with this parameter was performed using \( e_{\text{S}}^{\text{Cr}} \) = − 0.0105 in the published article. Thus, all calculated results associated with this parameter are correct in this article.

Sub-classifying patients with mild traumatic brain injury: A clustering approach based on baseline clinical characteristics and 90-day and 180-day outcomes

research teams that contributed to TRACK TBI Pilot, and the patients who participated. Author Contributions Todd J. Schwedt, Jing Li. Conceptualization: Bing Si, Gina Dumkrieger, Teresa Wu, Ross Zafonte ... , Jing Li. Funding acquisition: Teresa Wu, Ross Zafonte, Alex B. Valadka, David O. Okonkwo, Geoffrey T. Manley, David W. Dodick, Todd J. Schwedt, Jing Li. Investigation: Bing Si, Gina Dumkrieger, Teresa

Recycling spent Pleurotus eryngii substrate supplemented with Tenebrio molitor feces for cultivation of Agrocybe chaxingu

Purpose In the industrialized production of mushrooms usually only one flush of fruitbody is harvested, so that nutrients and energy in the substrate is not fully exploited. In this study, the spent Pleurotus eryngii substrate was recycled for the cultivation of Agrocybe chaxingu under ambient temperature. Method Six formulae were tested: (1) Control: 98% spent substrate, 1...

Dual-electrochromic bipolar electrode-based universal platform for the construction of various visual advanced logic devices

A universal logic platform based on dual-electrochromic bipolar electrodes (BPEs) for the operation of various visual advanced logic devices was designed and constructed for the first time. Two BPEs separated by three reaction channels filled with different reaction solutions constituted the closed BPE system and were used as the initial state. Under different input combinations...

Response of soil organic carbon fractions, microbial community composition and carbon mineralization to high-input fertilizer practices under an intensive agricultural system

. Methodology: Huijun Wu, Bisheng Wang. Resources: Dianxiong Cai, Jiancheng Zhang. Supervision: Baoguo Li, Jiancheng Zhang. Writing ± original draft: Jing Li. Writing ± review & editing: Xueping Wu, Mesfin

Long noncoding RNA H19 promotes transforming growth factor-β-induced epithelial–mesenchymal transition by acting as a competing endogenous RNA of miR-370-3p in ovarian cancer cells

Long noncoding RNA H19 promotes transforming growth factor-beta-induced epithelial-mesenchymal transition by acting as a competing endogenous RNA of miR-370-3p in ovarian cancer cells Jing Li

Optimal Shape Control of Piezoelectric Intelligent Structure Based on Genetic Algorithm

Shape variation induced by mismachining tolerance, humidity and temperature of the working environment, material wear and aging, and unknown external load disturbances have a relatively large influence on the dynamic shape of a mechanical structure. When integrating piezoelectric elements into the main mechanical structure, active control of the structural shape is realized by...

Optimal Shape Control of Piezoelectric Intelligent Structure Based on Genetic Algorithm

Shape variation induced by mismachining tolerance, humidity and temperature of the working environment, material wear and aging, and unknown external load disturbances have a relatively large influence on the dynamic shape of a mechanical structure. When integrating piezoelectric elements into the main mechanical structure, active control of the structural shape is realized by...

Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells

Scientific RepoRts | through downregulation of PI3K? mediated PI3K/AKT/mTOR/p70S6K/ Hong-Wei Zhang Jin-Jiao Hu Ruo-Qiu Fu Xin Liu Yan-Hao Zhang Jing Li Lei Liu Yu-Nong Li Qin Deng Qing-Song Luo Qin