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Cardiac involvement in patients with primary biliary cholangitis: A 14-year longitudinal survey-based study

. Author Contributions Conceptualization: Fengchun Zhang. Data curation: Sainan Bian, Hua Chen, Li Wang, Yunyun Fei, Yunjiao Yang, Linyi Peng, Yongzhe Li, Fengchun Zhang. Formal analysis: Sainan Bian ... , Hua Chen, Fengchun Zhang. Funding acquisition: Li Wang, Fengchun Zhang. Supervision: Fengchun Zhang. 7 / 9 Validation: Fengchun Zhang. Writing ± original draft: Sainan Bian, Hua Chen. Writing

Clinical characteristics and risk factors for overlapping rheumatoid arthritis and Sjögren’s syndrome

This study investigated the clinical characteristics and risk factors for overlapping rheumatoid arthritis and Sjögren’s syndrome (RA/SS). Patients with RA/SS in Peking Union Medical College Hospital from January 2012 to January 2017 were retrospectively analysed and compared to those of sex- and age–matched RA or SS controls. Logistic regression analysis was used to identify...

Identification of microR-106b as a prognostic biomarker of p53-like bladder cancers by ActMiR

R01-AG046170, U01-HG008451); and the Spanish Society of Medical Oncology to ACL. Author information AffiliationsDepartment of Genetics and Genomic Sciences, New York, NY, USAEunjee Lee, Li Wang & Jun ... ZhuIcahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USAEunjee Lee, Li Wang & Jun ZhuSema4, a Mount Sinai venture, Stamford, CT, USAEunjee Lee, Li

Reactive Oxygen Species Generation in Human Cells by a Novel Magnetic Resonance Imaging Contrast Agent

Received 12 October 2017; Accepted 19 February 2018; Published 26 March 2018 Academic Editor: Robert Tanguay Copyright © 2018 Li Wang et al. This is an open access article distributed under the Creative

Integrated approach for identifying and evaluating the quality of Marsdenia tenacissima in the medicine market

: Yan-li Wang, Hai-ping Zhang. Methodology: Yu-long Wei, Yue Zhu. Software: Ning Yu, Yu-long Wei. Supervision: Yue Zhu. Validation: Ning Zhu, Yan-li Wang, Hai-ping Zhang. Writing ± original draft

A Loss of Function Screen of Epigenetic Modifiers and Splicing Factors during Early Stage of Cardiac Reprogramming

Direct reprogramming of cardiac fibroblasts (CFs) to induced cardiomyocytes (iCMs) is a newly emerged promising approach for cardiac regeneration, disease modeling, and drug discovery. However, its potential has been drastically limited due to the low reprogramming efficiency and largely unknown underlying molecular mechanisms. We have previously screened and identified...

Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4

 & Haisheng Zhou AuthorsSearch for Li Wang in:Nature Research journals • PubMed • Google Scholar Search for Jing-jing Li in:Nature Research journals • PubMed • Google Scholar Search for Li-yu Guo in:Nature

Agreement Between the JCDCG, Revised NCEP-ATPIII, and IDF Definitions of Metabolic Syndrome in a Northwestern Chinese Population

authors have made a significant contribution to this manuscript. Fei Sun and Bin Gao contributed equally to this work. Qiuhe Ji was responsible for the study design. Fei Sun, Bin Gao, and Li Wang ... Company, and Medtronic, and received research grants from Novo Nordisk, Merck Sharp & Dohme China, and AstraZeneca. The remaining authors (Fei Sun, Bin Gao, Li Wang, Ying Xing, Jie Ming, Jie Zhou, Jianfang

Entrainment characteristics of fine particles under high speed airflow

Fine silicon particles (mean size of 2.7 μm) are used as entrained materials, and the entrainment characteristics of fine particles are investigated in a cylindrical fluidized-bed (inner diameter of 28 mm and height of 1000 mm) under high speed airflow. The effects of the volume flow of gas (Q, 1 m3/h to 2.5 m3/h), the number of holes (N, 1 to 4), the size of holes (D, 1 mm to 3...

Entrainment characteristics of fine particles under high speed airflow

Fine silicon particles (mean size of 2.7 μm) are used as entrained materials, and the entrainment characteristics of fine particles are investigated in a cylindrical fluidized-bed (inner diameter of 28 mm and height of 1000 mm) under high speed airflow. The effects of the volume flow of gas (Q, 1 m3/h to 2.5 m3/h), the number of holes (N, 1 to 4), the size of holes (D, 1 mm to 3...

Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking

Jakmunee Copyright © 2018 Ya-Li Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking

Tyrosinase (TYR) is a rate-limiting enzyme in the synthesis of melanin, while direct TYR inhibitors are a class of important clinical antimelanoma drugs. This study established a spectrum-effect relationship analysis method and high-performance liquid chromatography-mass spectrometry (LC-MS) analysis method to screen and identify the active ingredients that inhibited TYR in...

Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking

Jakmunee Copyright © 2018 Ya-Li Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

Discovery and Verification of Gelsolin as a Potential Biomarker of Colorectal Adenocarcinoma in a Chinese Population: Examining Differential Protein Expression using an Itraq Labelling-Based Proteomics Approach

labelling-based proteomics approach Nai-Jun Fan Chun-Fang Gao Chang-Song Wang Jing-Jing Lv Guang Zhao Xin-Hua Sheng Xiu-Li Wang Dong-Hui Li Qing-Yin Liu Jian Yin N-J Fan, C-F Gao, C-S Wang, et al. Discovery ... design of this study. Chang-song Wang, Jian-Yin and Qing-yin Liu contributed to the validation of gelsolin. JingJing Lv, Guang Zhao, Xin-hua Sheng, Xiu-li Wang and Dong-hui Li contributed to samples and

A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel

Piezo1 represents a prototype of eukaryotic mechanotransduction channels. The full-length 2547-residue mouse Piezo1 possesses a unique 38-transmembrane-helix (TM) topology and is organized into a three-bladed, propeller-shaped architecture, comprising a central ion-conducting pore, three peripheral blade-like structures, and three 90-Å-long intracellular beam-resembling...

Functional characterization of KS-type dehydrin ZmDHN13 and its related conserved domains under oxidative stress

supported by the Grants from the Shandong Province Natural Science Foundation (ZR2016CQ34) and the Nation Natural Science Foundation of China (Nos 31271633). Author Contributions Yang Liu, Li Wang and ... Dequan Li designed the experiments. Yang Liu, Li Wang and Tianpeng Zhang performed the experiments and analyzed the data. Yang Liu and Dequan Li wrote the article. Dequan Li and Xinghong Yang revised the

Online Traffic Condition Evaluation Method for Connected Vehicles Based on Multisource Data Fusion

With the development of connected vehicle (CV) and Vehicle to X (V2X) communication, more traffic data is being collected from the road network. In order to predict future traffic condition from connected vehicles’ data in real-time, we present an online traffic condition evaluation model utilizing V2X communication. This model employs the Analytic Hierarchy Process (AHP) and the...

Online Traffic Condition Evaluation Method for Connected Vehicles Based on Multisource Data Fusion

With the development of connected vehicle (CV) and Vehicle to X (V2X) communication, more traffic data is being collected from the road network. In order to predict future traffic condition from connected vehicles’ data in real-time, we present an online traffic condition evaluation model utilizing V2X communication. This model employs the Analytic Hierarchy Process (AHP) and the...

Proinflammatory Factors Mediate Paclitaxel-Induced Impairment of Learning and Memory

The authors declare no conflict of interest. Authors? Contributions Xiu-Li Wang, Zhao Li, Yue-Xian Guo, and Hai-Lin Zhang participated in the research design. Zhao Li, Shuang Zhao, Peng Liu, and Fei ... -Fei Liu conducted the experiments. Zhao Li, Shuang Zhao, Peng Liu, and Xiu-Li Wang performed the data analysis. Zhao Li, Shuang Zhao, Peng Liu, Xiu-Li Wang, Yue-Xian Guo, and Hai-Lin Zhang wrote or

Proinflammatory Factors Mediate Paclitaxel-Induced Impairment of Learning and Memory

Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, China Correspondence should be addressed to Xiu-Li Wang; moc.621@113lxgnaw Received 29 September 2017; Revised 17 December 2017; Accepted 8 ... of TNF-α synthesis recovered the impaired learning and memory function in paclitaxel-treated rats. Conflicts of Interest The authors declare no conflict of interest. Authors’ Contributions Xiu-Li Wang