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Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice

,3 Qing Wang,1 Li Zeng,4 and Guihua Xu1 1School of Nursing, Nanjing University of Chinese Medicine, Nanjing 210023, China 2Medical College, Nantong University, Nantong 226001, China 3School of Basic

Low-Temperature Stress during Capped Brood Stage Increases Pupal Mortality, Misorientation and Adult Mortality in Honey Bees

Honey bees (Apis mellifera) are key pollinators, playing a vital role in ecosystem maintenance and stability of crop yields. Recently, reduced honey bee survival has attracted intensive attention. Among all other honey bee stresses, temperature is a fundamental ecological factor that has been shown to affect honey bee survival. Yet, the impact of low temperature stress during...

A genome-wide expression profile analysis reveals active genes and pathways coping with phosphate starvation in soybean

Background Phosphorus is one of the most important macronutrients that is required for plant growth and development. However, stress under low-P conditions has become a limiting factor that affects crop yields and qualities. Plants have developed strategies to cope with this, while few genes associated with low-P tolerance have been identified in soybean. Results Genome-wide...

Connecting neutrino masses and dark matter by high-dimensional lepton number violation operator

We propose a new model with the Majorana neutrino masses generated at two-loop level, in which the lepton number violation (LNV) processes, such as neutrino-less double beta decays, are mainly induced by the dimension-7 LNV effective operator \( {\mathcal{O}}_7={\overline{l}}_R^c{\gamma}^{\mu }{L}_L\left({D}_{\mu}\varPhi \right)\varPhi \varPhi \). Note that it is necessary to...

Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes

Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes Fei Gao, Ningjie Ma, Hong Zhou, Qing Wang, Hao Zhang, Pu Wang, Haoli

ABO blood type correlates with survival in hepatocellular carcinoma following hepatectomy

ABO blood types are associated with the prognosis of several malignancies. However, the role of the ABO blood type in hepatocellular carcinoma (HCC) remains elusive. Here, we evaluated the prognostic role of the ABO blood group in 691 HCC patients after hepatectomy by Cox regression analysis. A prognostic nomogram was generated to predict the 3 and 5-year overall survival (OS). A...

Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation

The ribosomal RNA (rRNA) gene encodes rRNA for protein synthesis. Aberrant expression of the rRNA gene has been generally observed in tumor cells and levels of its promoter methylation as an epigenetic regulator affect rRNA gene transcription. The possible relationship between expression and promoter methylation of rDNA has not been examined in human clinical cervical cancer...

Distribution of carbon, nitrogen and phosphorus in coastal wetland soil related land use in the Modern Yellow River Delta

Research journals • PubMed • Google ScholarSearch for Bo Guan in:Nature Research journals • PubMed • Google ScholarSearch for Qing Wang in:Nature Research journals • PubMed • Google Scholar Contributions ... interpreted the remote sensing images and prepared the Figures 1, 2 and 4. Guangxuan Han, Guangmei Wang and Bo Guan did the field land use survey and designed the filed monitoring sites. Qing Wang complement

Fluoroquinolone resistance in bacteremic and low risk febrile neutropenic patients with cancer

Background The low risk febrile neutropenic patients with Multinational Association for Supportive Care in Cancer (MASCC) score of more than 20 are recommended to be treated with fluoroquinolone-based oral treatment by the National Comprehensive Cancer Network (NCCN) guideline. This recommendation relies, at least partially, on the high sensitivity of the blood culture isolates...

Identification and Evaluation of Reference Genes for Accurate Transcription Normalization in Safflower under Different Experimental Conditions

Safflower (Carthamus tinctorius L.) has received a significant amount of attention as a medicinal plant and oilseed crop. Gene expression studies provide a theoretical molecular biology foundation for improving new traits and developing new cultivars. Real-time quantitative PCR (RT-qPCR) has become a crucial approach for gene expression analysis. In addition, appropriate...

Overexpression of Hypo-Phosphorylated IκBβ at Ser313 Protects the Heart against Sepsis

IκBβis an inhibitor of nuclear factor kappa B(NF-κB) and participates in the cardiac response to sepsis. However, the role of the hypo-phosphorylated form of IκBβ at Ser313, which can be detected during sepsis, is unknown. Here, we examined the effects of IκBβ with a mutation at Ser313→Ala313 on cardiac damage induced by sepsis. Transgenic (Tg) mice were generated to overexpress...

Aqueous Synthesis of ZnSe/ZnS-2-R-Benzothiazole Nanocrystals with White Emission

We prepared water-soluble white light-emitting ZnSe/ZnS-2-R-benzothiazole nanocrystals (NCs), R = 2-hydroxy-5-(2,5-dimethyl-thienyl)-phenyl. The penicillamine (Pen) capped ZnSe/ZnS NCs were firstly prepared with high photoluminescence quantum yields (PL QY) of 40%. Then they bond to 2-R-benzothiazole molecules, resulting in white light-emitting ZnSe/ZnS-2-R-benzothiazole NCs with...

Aqueous Synthesis of ZnSe/ZnS-2-R-Benzothiazole Nanocrystals with White Emission

We prepared water-soluble white light-emitting ZnSe/ZnS-2-R-benzothiazole nanocrystals (NCs), R = 2-hydroxy-5-(2,5-dimethyl-thienyl)-phenyl. The penicillamine (Pen) capped ZnSe/ZnS NCs were firstly prepared with high photoluminescence quantum yields (PL QY) of 40%. Then they bond to 2-R-benzothiazole molecules, resulting in white light-emitting ZnSe/ZnS-2-R-benzothiazole NCs with...

MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress

Li, and Jiaqiao Zhang conceived and designed the study. Yuchao Lu, Deng He, Baolong Qin, Yufeng Wang, Qing Wang, Chuou Xu, and Jiaqiao Zhang performed the experiments. Henglong Hu and Jiaqiao Zhang

MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress

Li, and Jiaqiao Zhang conceived and designed the study. Yuchao Lu, Deng He, Baolong Qin, Yufeng Wang, Qing Wang, Chuou Xu, and Jiaqiao Zhang performed the experiments. Henglong Hu and Jiaqiao Zhang

Identification and evaluation of reference genes in the Chinese white wax scale insect Ericerus pela

Background The Chinese white wax scale insect, Ericerus pela, is a well-known resource insect. The females and males are dramatically distinct at each developmental stage. We sought to identify suitable reference genes to use as internal controls in molecular research on E. plea. Results geNorm, RefFinder and Normfinder analyses showed that ßTub-2 was the best reference gene...

Cystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units

Cystatin C (CYS C, Cst3) is an endogenous cysteine protease inhibitor that plays neuroprotective roles in neurodegenerative diseases. We aimed to explore the association of CYS C with Parkinson’s disease (PD) models and investigate its involvement in the role of neurovascular units (NVUs) in PD neuro-pathogenesis. We used A53T α-synuclein (SNCA) transgenic mice and 6...

Integrated Control of Hydromechanical Variable Transmissions

A hydromechanical variable transmission (HMT) has advantages of continuous variation and high efficiency. So it is one of the ideal transmissions of heavy vehicles. The continuous speed varying process involves speed governing in range and range shift. Integrated control strategy of the HMT is proposed in this paper. The algorithm of the asymmetric saturated incremental...

Integrated Control of Hydromechanical Variable Transmissions

A hydromechanical variable transmission (HMT) has advantages of continuous variation and high efficiency. So it is one of the ideal transmissions of heavy vehicles. The continuous speed varying process involves speed governing in range and range shift. Integrated control strategy of the HMT is proposed in this paper. The algorithm of the asymmetric saturated incremental...