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211 papers found.
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Body Mass Index and Mortality: A 10-Year Prospective Study in China

Although several studies have evaluated the role of body weight as a risk factor for mortality, most studies have been conducted in Western populations and the findings remain controversial. We performed a prospective study to examine the association between body mass index (BMI) and all-cause mortality in Yinzhou District, Ningbo, China. At baseline, 384,533 subjects were...

Experimental research on dynamic imbibition of fractured heavy oil reservoir under different temperatures

Fractured reservoirs contain a large fraction of the world supply of oil and imbibition is one of the dominant recovery mechanisms. For fractured reservoirs containing heavy oils or tars, oil viscosity is high and it is hard to get a good development effect at reservoir temperature. However, if thermal methods are adopted, the oil viscosity will decrease sharply as temperature...

Improvements in quality of life associated with biphasic insulin aspart 30 in type 2 diabetes patients in China: results from the A1chieve® observational study

Background Based on the 24-week, prospective, non-interventional, observational study, A1chieve®, we investigated how health-related quality of life (HRQoL) changed, and the predictors of such changes, in Chinese people with type 2 diabetes mellitus (T2DM) after starting with, or switching to, biphasic insulin aspart 30 (BIAsp 30). Methods In total, 8,578 people with T2DM...

Preliminary study of the association between corneal histocytological changes and surgically induced astigmatism after phacoemulsification

Background Surgically induced astigmatism (SIA) was one of the factors that influences the desirable refractive outcome, and it was related to the length, type, location, structure of the incision and to the suture closure technique, etc. The aim was to evaluate the association of corneal histocytological changes with SIA after phacoemulsification. Methods The study enrolled 68...

Development of a Threshold Model to Predict Germination of Populus tomentosa Seeds after Harvest and Storage under Ambient Condition

Effects of temperature, storage time and their combination on germination of aspen (Populus tomentosa) seeds were investigated. Aspen seeds were germinated at 5 to 30°C at 5°C intervals after storage for a period of time under 28°C and 75% relative humidity. The effect of temperature on aspen seed germination could not be effectively described by the thermal time (TT) model...

Retraction Note to: Correlations of IFN-γ genetic polymorphisms with susceptibility to breast cancer: a meta-analysis

, People's Republic of China 1 College of Environment and Chemical Engineering, Yanshan University , Hebei Street No. 438, Qinhuangdao 066004 , People's Republic of China 2 Qing-Wang Li 3 College of Animal

Security and cost comparison of INR self-testing and conventional hospital INR testing in patients with mechanical heart valve replacement

Background International normalized ratio (INR) self-testing can improve the management of anticoagulation therapy with warfarin for the patients following mechanical heart valve replacement. Several reviews and studies have demonstrated self-management as an option to improve patient’s outcome considerably after mechanical heart valve replacement. We sought to analyze the...

Genetic diversity of Plasmodium vivax population before elimination of malaria in Hainan Province, China

Shan-Qing Wang Background: Hainan Province is one of the most severe endemic regions with high transmission of Plasmodium falciparum and Plasmodium vivax in China. However, the incidence of P

In Depth Analysis on the Binding Sites of Adamantane Derivatives in HCV (Hepatitis C Virus) p7 Channel Based on the NMR Structure

Background The recently solved solution structure of HCV (hepatitis C virus) p7 ion channel provides a solid structure basis for drug design against HCV infection. In the p7 channel the ligand amantadine (or rimantadine) was determined in a hydrophobic pocket. However the pharmocophore (−NH2) of the ligand was not assigned a specific binding site. Results The possible binding...

Biofortification of rice with the essential amino acid lysine: molecular characterization, nutritional evaluation, and field performance

Rice (Oryza sativa L.), a major staple crop worldwide, has limited levels of the essential amino acid lysine. We previously produced engineered rice with increased lysine content by expressing bacterial aspartate kinase and dihydrodipicolinate synthase and inhibiting rice lysine ketoglutarate reductase/saccharopine dehydrogenase activity. However, the grain quality, field...

Pathogenicity and tissue distribution of grass carp reovirus after intraperitoneal administration

Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhage and causes significant loss of fingerlings. However, little is known about how the virus is distributed in organs and tissues. The aim of the present study was to investigate the distribution of different GCRV stains in tissues and organs of grass carp. The pathogenicity and tissue distribution of GCRV...

Cryo-ablation improves anti-tumor immunity through recovering tumor educated dendritic cells in tumor-draining lymph nodes

Cryo-ablation improves anti-tumor immunity through recovering tumor educated dendritic cells in tumor-draining lymph nodes Xiao-Zheng He,1,2 Qi-Fu Wang,1,2 Shuai Han,3 Hui-Qing Wang,1,2 Yong-Yi Ye

Transcriptome profiling of the cold response and signaling pathways in Lilium lancifolium

Background Lilium lancifolium, a very important cold-resistant wild flower for lily cold resistance breeding, is widely distributed in southwestern and northeastern China. To gain a better understanding of the cold signaling pathway and the molecular metabolic reactions involved in the cold response, we performed a genome-wide transcriptional analysis using RNA-Seq. Results...

Physical Activity and Lung Function Growth in a Cohort of Chinese School Children: A Prospective Study

Backgrounds/objectives Evidence on the association between physical activity and lung function in children is sparse. The aim of this study was to evaluate children’s lung function growth in relation to their physical activity level in Chinese children. Methods A total of 1713 school children aged 9.89±0.86 years who were asthma-free at baseline were followed-up for 18 months...

Non-Newtonian flow characterization of heavy crude oil in porous media

As a temperature-sensitive non-Newtonian fluid, the seepage of heavy crude oil in porous media shows the non-linear characteristics. The flowing behavior of three heavy oils through porous media is experimentally investigated, and the influence of temperature and pressure-drop on this flowing process is also described. Thereafter, based on the flowing behavior of heavy crude oil...

Functional characterization of Klippel–Trenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation and angiogenesis during embryogenesis

Specification of arteries and veins is a key process for establishing functional vasculature during embryogenesis and involves distinctly different signaling mechanisms. Vascular endothelial growth factor-A (VEGFA) is required for differentiation of arteries; however, the upstream angiogenic factor for vein specification is unknown. Klippel–Trenaunay syndrome (KTS) is a...

Relationship of redundant Th17 cells and IL-17A, but not IL-17 F, with the severity of obstructive sleep apnoea/hypopnoea syndrome (OSAHS)

Background The pathogenesis of obstructive sleep apnoea/hypopnoea syndrome (OSAHS), a highly prevalent disease, is not completely understood. The purpose of this study was to investigate the contributions of Th17 cells and the Th17-associated cytokines IL-17A and IL-17 F to OSAHS. Methods 46 male patients with a clinical suspicion of OSAHS were enrolled and divided into four...

The Structure of Parafermion Vertex Operator Algebras: General Case

The structure of the parafermion vertex operator algebra associated to an integrable highest weight module for any affine Kac-Moody algebra is studied. In particular, a set of generators for this algebra has been determined.

Effects of CD40 ligation combined with chemotherapy drugs on human breast cancer cell lines

Objective To investigate the influence of recombinant human CD40 ligand (rhCD40L) on the biological behaviour of breast cancer cells.

A Novel C-Type Lysozyme from Mytilus galloprovincialis: Insight into Innate Immunity and Molecular Evolution of Invertebrate C-Type Lysozymes

A c-type lysozyme (named as MgCLYZ) gene was cloned from the mussel Mytilus galloprovincialis. Blast analysis indicated that MgCLYZ was a salivary c-type lysozyme which was mainly found in insects. The nucleotide sequence of MgCLYZ was predicted to encode a polypeptide of 154 amino acid residues with the signal peptide comprising the first 24 residues. The deduced mature peptide...