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KPCA-ESN Soft-Sensor Model of Polymerization Process Optimized by Biogeography-Based Optimization Algorithm

For solving the problem that the conversion rate of vinyl chloride monomer (VCM) is hard for real-time online measurement in the polyvinyl chloride (PVC) polymerization production process, a soft-sensor modeling method based on echo state network (ESN) is put forward. By analyzing PVC polymerization process ten secondary variables are selected as input variables of the soft...

Exploiting ontology graph for predicting sparsely annotated gene function

Motivation: Systematically predicting gene (or protein) function based on molecular interaction networks has become an important tool in refining and enhancing the existing annotation catalogs, such as the Gene Ontology (GO) database. However, functional labels with only a few (<10) annotated genes, which constitute about half of the GO terms in yeast, mouse and human, pose a...

ROR1 is a novel prognostic biomarker in patients with lung adenocarcinoma

Currently, there is no reliable biomarker to clinically predict the prognosis of lung adenocarcinoma (ADC). The receptor-tyrosine-kinase like orphan receptor 1 (ROR1) is reported to be overexpressed and associated with poor prognosis in several tumors. This study aimed to examine the expression of ROR1 and evaluate its prognostic significance in human lung ADC patients. In this...

Transcriptome sequencing and metabolite analysis for revealing the blue flower formation in waterlily

Background Waterlily (Nymphaea spp.), a perennial herbaceous aquatic plant, is divided into two ecological groups: hardy waterlily and tropical waterlily. Although the hardy waterlily has no attractive blue flower cultivar, its adaptability is stronger than tropical waterlily because it can survive a cold winter. Thus, breeding hardy waterlily with real blue flowers has become an...

Development of a GeXP-multiplex PCR assay for the simultaneous detection and differentiation of six cattle viruses

Foot-and-mouth disease virus (FMDV), Bluetongue virus (BTV), Vesicular stomatitis Virus (VSV), Bovine viral diarrheal (BVDV), Bovine rotavirus (BRV), and Bovine herpesvirus 1 (IBRV) are common cattle infectious viruses that cause a great economic loss every year in many parts of the world. A rapid and high-throughput GenomeLab Gene Expression Profiler (GeXP) analyzer-based...

Automatic time-shift alignment method for chromatographic data analysis

Time shift among samples remains a significant challenge in data analysis, such as quality control of natural plant extracts and metabolic profiling analysis, because this phenomenon may lead to invalid conclusions. In this work, we propose a new time shift alignment method, namely, automatic time-shift alignment (ATSA), for complicated chromatographic data analysis. This...

A Scaled Conjugate Gradient Method for Solving Monotone Nonlinear Equations with Convex Constraints

24 April 2013; Revised 5 November 2013; Accepted 5 November 2013 Academic Editor: Saeid Abbasbandy Copyright © 2013 Sheng Wang and Hongbo Guan. This is an open access article distributed under the

Bifurcations for a deterministic SIR epidemic model in discrete time

Xiaoliang Zhou 0 Xiaopei Li 0 Wu-Sheng Wang 0 Department of Mathematics, Zhanjiang Normal University , Zhanjiang, Guangdong 524048, P.R. China In this paper, we are concerned with the theoretical

Establishing guidelines for CAR-T cells: challenges and considerations

T cells, genetically modified by chimeric antigen receptors (CAR-T), are endowed with specificity to a desired antigen and are cytotoxic to cells expressing the targeted antigen. CAR-T-based cancer immunotherapy is a promising therapy for curing hematological malignancy, such as acute lymphoid leukemia, and is promising for extending their efficacy to defeat solid tumors. To date...

A Class of Volterra-Fredholm Type Weakly Singular Difference Inequalities with Power Functions and Their Applications

We discuss a class of Volterra-Fredholm type difference inequalities with weakly singular. The upper bounds of the embedded unknown functions are estimated explicitly by analysis techniques. An application of the obtained inequalities to the estimation of Volterra-Fredholm type difference equations is given.

A Class of Volterra-Fredholm Type Weakly Singular Difference Inequalities with Power Functions and Their Applications

We discuss a class of Volterra-Fredholm type difference inequalities with weakly singular. The upper bounds of the embedded unknown functions are estimated explicitly by analysis techniques. An application of the obtained inequalities to the estimation of Volterra-Fredholm type difference equations is given.

Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients

• Google ScholarSearch for Lei Shi in:Nature Research journals • PubMed • Google ScholarSearch for Bin Gao in:Nature Research journals • PubMed • Google ScholarSearch for Fu-Sheng Wang in:Nature Research ... to Fu-Sheng Wang or Zheng Zhang. Supplementary information PDF files1.Suplemental Information Rights and permissions This work is licensed under a Creative Commons Attribution 4.0

Review of Research on Carbon-free Car

studied comprehensively from the scheme design and innovative design, mathematical modeling, research methods and other aspects of carbon-free car, discussed the research content and distribution characteristics of literature, summed up the general scheme and innovative design of carbon-free car, It provides a certain reference value for the design and research of carbon-free car.

Some Retarded Difference Inequalities of Product Form and Their Application

A class of new nonlinear retarded difference inequalities is established. An application of the obtained inequalities to the estimation of finite difference equations is given.

Some Retarded Difference Inequalities of Product Form and Their Application

A class of new nonlinear retarded difference inequalities is established. An application of the obtained inequalities to the estimation of finite difference equations is given.

Estimation of Unknown Functions of Iterative Difference Inequalities and Their Applications

We establish some new nonlinear retarded finite difference inequalities. The results that we propose here can be used as tools in the theory of certain new classes of finite difference equations in various difference situations. We also give applications of the inequalities to show the usefulness of our results.

Risk factors for infection after endoscopic ultrasonography-guided drainage of specific types of pancreatic and peripancreatic fluid collections (with video)

. Compliance with ethical standards Disclosures No conflict of interest has been declared by Jintao Guo, Linlin Feng, Siyu Sun, Nan Ge, Xiang Liu, Sheng Wang, Guoxin Wang, Beibei Sun. Open Access This article

Some Difference Inequalities for Iterated Sums with Applications

© 2013 Wu-Sheng Wang and Shanhe Wu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Spatiotemporal Variability and Change of the South China Spring Precipitation during 1961–2012

We analyze precipitation data from 47 meteorological stations spanning between 1961 and 2012 and NCEP/NCAR reanalysis to understand spatiotemporal variability and change of spring precipitation of South China and their relations to atmospheric circulations. Empirical orthogonal function (EOF) analysis and rotated EOF (REOF) are used to reveal dominant spatial structures of...