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Short-term effects of ambient air pollution and childhood lower respiratory diseases

The association between air pollution and childhood respiratory disease is inconsistent. In the present study, we investigated a short-term effect of ambient air pollutants and daily childhood lower respiratory diseases (CLRD). Daily air pollutants, weather data, and CLRD data were collected from January 2014 to April 2015 (452 days) in Nanjing, China. Time-series regression and...

Titanium Surface Priming with Phase-Transited Lysozyme to Establish a Silver Nanoparticle-Loaded Chitosan/Hyaluronic Acid Antibacterial Multilayer via Layer-by-Layer Self-Assembly

Objectives The formation of biofilm around implants, which is induced by immediate bacterial colonization after installation, is the primary cause of post-operation infection. Initial surface modification is usually required to incorporate antibacterial agents on titanium (Ti) surfaces to inhibit biofilm formation. However, simple and effective priming methods are still lacking...

The SsDREB Transcription Factor from the Succulent Halophyte Suaeda salsa Enhances Abiotic Stress Tolerance in Transgenic Tobacco

Enhancement, Cytogenetics Institute, Nanjing Agricultural University, Nanjing 210095, China Received 19 April 2015; Accepted 7 June 2015 Academic Editor: Marián Brestič Copyright © 2015 Xu Zhang et al ... this paper. Authors’ Contribution Xu Zhang and Xiaoxue Liu contributed equally to this paper. Acknowledgments This work was financially supported by the National Science and Technology Major Project

The SsDREB Transcription Factor from the Succulent Halophyte Suaeda salsa Enhances Abiotic Stress Tolerance in Transgenic Tobacco

Enhancement, Cytogenetics Institute, Nanjing Agricultural University, Nanjing 210095, China Received 19 April 2015; Accepted 7 June 2015 Academic Editor: Marián Brestič Copyright © 2015 Xu Zhang et al ... conflict of interests regarding the publication of this paper. Authors’ Contribution Xu Zhang and Xiaoxue Liu contributed equally to this paper. Acknowledgments This work was financially supported by the

NMR studies on the interactions between yeast Vta1 and Did2 during the multivesicular bodies sorting pathway

Wang Xu Zhang Cody J. Wild Maili Liu Zhaohui Xu Chunyang Cao ccao@mail OPEN As an AAA-ATPase, Vps4 is important for function of multivesicular bodies (MVB) sorting pathway, which involves in cellular

Association of Plasma Myeloperoxidase Level with Risk of Coronary Artery Disease in Patients with Type 2 Diabetes

Aims. This study aimed to investigate whether the change of plasma myeloperoxidase (MPO) level would be associated with the incidence of coronary artery disease (CAD) among diabetic patients. Methods. 339 patients with type 2 diabetes mellitus (DM) underwent coronary angiography. Of them, 204 cases had CAD and were assigned to CAD group and 135 cases without CAD were assigned to...

The Efficacy of Acupuncture for the Treatment of Sciatica: A Systematic Review and Meta-Analysis

Background. Sciatica is one of the most frequently reported complaints; it affects quality of life and reduces social and economic efficacy. Clinical studies on the efficacy of acupuncture therapy in sciatica are increasing, while systematic reviews assessing the efficacy of acupuncture therapy are still lacking. Objective. This study aims to assess the effectiveness of...

Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway

Myeloid-derived suppressor cells (MDSCs) have been known to be a key factor in the regulation of the immune system under numerous conditions such as tumors, infections, autoimmune diseases, and transplantations. In contrast to the proposed deleterious role of MDSCs in tumors and infections, MDSCs with their suppressive function are now proved to have the beneficial potential of...

Predicting Prostate Biopsy Outcomes: A Preliminary Investigation on Screening with Ultrahigh B-Value Diffusion-Weighted Imaging as an Innovative Diagnostic Biomarker

Background Routine screening of prostate specific antigen (PSA) is no longer recommended because of a high rate of over-diagnosis of prostate cancer (PCa). Objective To evaluate the efficacy of diffusion-weighted magnetic resonance imaging (DW-MRI) for PCa detection, and to explore the clinical utility of ultrahigh b-value DW-MRI in predicting prostate biopsy outcomes...

Isospectral Operators

Mu-Fa Chen 0 Xu Zhang 0 0 X. Zhang College of Applied Sciences, Beijing University of Technology , Beijing 100022, People's Republic of China For a large class of integral operators or second

Anordrin Eliminates Tamoxifen Side Effects without Changing Its Antitumor Activity

Tamoxifen is administered for estrogen receptor positive (ER+) breast cancers, but it can induce uterine endometrial cancer and non-alcoholic fatty liver disease (NAFLD). Importantly, ten years of tamoxifen treatment has greater protective effect against ER+ breast cancer than five years of such treatment. Tamoxifen was also approved by the FDA as a chemopreventive agent for...

Robust Analysis and Parameters Identification of the Nonlinear Multistage Dynamical System in Batch Fermentation of Glycerol

; Accepted 3 September 2014; Published 21 October 2014 Academic Editor: Henggui Zhang Copyright © 2014 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution

Robust Analysis and Parameters Identification of the Nonlinear Multistage Dynamical System in Batch Fermentation of Glycerol

; Accepted 3 September 2014; Published 21 October 2014 Academic Editor: Henggui Zhang Copyright © 2014 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution

Robust Analysis and Parameters Identification of the Nonlinear Multistage Dynamical System in Batch Fermentation of Glycerol

; Accepted 3 September 2014; Published 21 October 2014 Academic Editor: Henggui Zhang Copyright © 2014 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution

A Tissue-Specific Scaffold for Tissue Engineering-Based Ureteral Reconstruction

Terminally differentiated somatic cells can rapidly change phenotypes when they are isolated from their native tissue and cultured in vitro. This problem may become a barrier to tissue engineering-based organ reconstruction, which utilizes somatic cells. The present study was designed to validate the feasibility of maintaining the urothelial cell phenotype in a tissue-specific...

Facilitation of Synaptic Transmission in the Anterior Cingulate Cortex in Viscerally Hypersensitive Rats

Electrophysiological studies have shown the enhanced response of anterior cingulate cortex (ACC) to colorectal distension in viscerally hypersensitive (VH) rats, which can be observed up to 7 weeks following colonic anaphylaxis, independent of colon inflammation, suggesting a mechanism for learning and triggering of pain memories in the ACC neuronal circuitry. Activity-dependent...

Exosomes in cancer: small particle, big player

Exosomes have emerged as a novel mode of intercellular communication. Exosomes can shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs from one cell to another, leading to the exchange of genetic information and reprogramming of the recipient cells. Increasing evidence suggests that tumor cells release excessive amount of exosomes, which may...

Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Localized and Advanced Prostate Cancer: A Systematic Review and Meta-Analysis

Objective and Background Increasing evidence suggests that inflammation plays an essential role in cancer development and progression. The inflammation marker neutrophil–lymphocyte ratio (NLR) is correlated with prognosis across a wide variety of tumor types, but its prognostic value in prostate cancer (PCa) remains controversial. In the present meta-analysis, the prognostic...

High-Columbic-Efficiency Lithium Battery Based on Silicon Particle Materials

Micro-sized polycrystalline silicon particles were used as anode materials of lithium-ion battery. The columbic efficiency of the first cycle reached a relatively high value of 91.8 % after prelithiation and increased to 99 % in the second cycle. Furthermore, columbic efficiency remained above 99 % for up to 280+ cycles. The excellent performances of the batteries were the...

Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways

Immunotherapy and Medical College of Nanchang University, and Jiangxi Academy of Medical Sciences, Nanchang, ChinaHongmei Wang, Jun Shi, Qing Li, Zhu-Xu Zhang & Weiping MinDepartment of Surgery, Pathology, and ... Oncology, University of Western Ontario, London, CanadaHongmei Wang, Xusheng Zhang, Xiufen Zheng, Terry Zwiep, Qing Li, Douglas Quan, Zhu-Xu Zhang & Weiping MinMulti-Organ Transplant Program, London Health