Advanced search    

Search: authors:"Hui Fang"

162 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Patterns of Spontaneous Brain Activity in Amyotrophic Lateral Sclerosis: A Resting-State fMRI Study

By detecting spontaneous low-frequency fluctuations (LFF) of blood oxygen level–dependent (BOLD) signals, resting-state functional magnetic resonance imaging (rfMRI) measurements are believed to reflect spontaneous cerebral neural activity. Previous fMRI studies were focused on the examination of motor-related areas and little is known about the functional changes in the extra...

Endogenous Molecules Induced by a Pathogen-Associated Molecular Pattern (PAMP) Elicit Innate Immunity in Shrimp

Invertebrates rely on an innate immune system to combat invading pathogens. The system is initiated in the presence of cell wall components from microbes like lipopolysaccharide (LPS), β-1,3-glucan (βG) and peptidoglycan (PG), altogether known as pathogen-associated molecular patterns (PAMPs), via a recognition of pattern recognition protein (PRP) or receptor (PRR) through...

Identification of Drug Resistant Mutations in HIV-1 CRF07_BC Variants Selected by Nevirapine In Vitro

Since the antiretroviral therapy (ART) was introduced to patients infected by human immunodeficiency virus (HIV), the HIV related mortality and morbidity have been significantly reduced. The major obstacle for long-term successful anti-HIV treatment is the emergence of drug resistant mutants. Current data of drug resistance was mainly obtained on HIV-1 subtype B but rarely on non...

Anomalous luminescence phenomena of indium-doped ZnO nanostructures grown on Si substrates by the hydrothermal method

In recent years, zinc oxide (ZnO) has become one of the most popular research materials due to its unique properties and various applications. ZnO is an intrinsic semiconductor, with a wide bandgap (3.37 eV) and large exciton binding energy (60 meV) making it suitable for many optical applications. In this experiment, the simple hydrothermal method is used to grow indium-doped...

Activin A induces growth arrest through a SMAD- dependent pathway in hepatic progenitor cells

Background Activin A, an important member of transforming growth factor-β superfamily, is reported to inhibit proliferation of mature hepatocyte. However, the effect of activin A on growth of hepatic progenitor cells is not fully understood. To that end, we attempted to evaluate the potential role of activin A in the regulation of hepatic progenitor cell proliferation. Results...

Existence of positive periodic solutions for delayed predator-prey patch systems with stocking

Hindawi Publishing Corporation International Journal of Mathematics and Mathematical Sciences Volume 2006 0 Hui Fang: Faculty of Information Science and Engineering, Ningbo Institute of Technology

Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System

Xenoestrogens are either natural or synthetic compounds that mimic the effects of endogenous estrogen. These compounds, such as bisphenol-A (BPA), and phthalates, are commonly found in plastic wares. Exposure to these compounds poses major risk to human health because of the potential to cause endocrine disruption. There is huge demand for a wide range of chemicals to be assessed...

Multiple periodic solutions for a discrete time model of plankton allelopathy

We study a discrete time model of the growth of two species of plankton with competitive and allelopathic effects on each other N1(k+1) = N1(k)exp{r1(k)-a11(k)N1(k)-a12(k)N2(k)-b1(k)N1(k)N2(k)}, N2(k+1) = N2(k)exp{r2(k)-a21(k)N2(k)-b2(k)N1(k)N1(k)N2(k)}. A set of sufficient conditions is obtained for the existence of multiple positive periodic solutions for this model. The...

Anthrax Lethal Toxin Disrupts Intestinal Barrier Function and Causes Systemic Infections with Enteric Bacteria

A variety of intestinal pathogens have virulence factors that target mitogen activated protein kinase (MAPK) signaling pathways, including Bacillus anthracis. Anthrax lethal toxin (LT) has specific proteolytic activity against the upstream regulators of MAPKs, the MAPK kinases (MKKs). Using a murine model of intoxication, we show that LT causes the dose-dependent disruption of...

Frailty and Its Impact on Health-Related Quality of Life: A Cross-Sectional Study on Elder Community-Dwelling Preventive Health Service Users

Background The purpose of this study was to identify the incidence of frailty and to investigate the relationship between frailty status and health-related quality of life (HRQoL) in the community-dwelling elderly population who utilize preventive health services. Methods People aged 65 years and older who visited a medical center in Taipei City from March to August in 2011 for...

Response gene to complement-32 enhances metastatic phenotype by mediating transforming growth factor beta-induced epithelial-mesenchymal transition in human pancreatic cancer cell line BxPC-3

Background Response gene to complement-32 (RGC-32) is comprehensively expressed in many kinds of tissues and has been reported to be expressed abnormally in different kinds of human tumors. However, the role of RGC-32 in cancer remains controversial and no reports have described the effect of RGC-32 in pancreatic cancer. The present study investigated the expression of RGC-32 in...

When is Cancer Care Cost-Effective? A Systematic Overview of Cost–Utility Analyses in Oncology

New cancer treatments pose a substantial financial burden on health-care systems, insurers, patients, and society. Cost–utility analyses (CUAs) of cancer-related interventions have received increased attention in the medical literature and are being used to inform reimbursement decisions in many health-care systems. We identified and reviewed 242 cancer-related CUAs published...

Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity

, SingaporeCharmian Hui Fang Yeo & Wee Han Ang AuthorsSearch for Zenita Adhireksan in:Nature Research journals • PubMed • Google ScholarSearch for Gabriela E. Davey in:Nature Research journals • PubMed • Google ... for Charmian Hui Fang Yeo in:Nature Research journals • PubMed • Google ScholarSearch for Wee Han Ang in:Nature Research journals • PubMed • Google ScholarSearch for Peter Dröge in:Nature Research

Aggressive natural killer-cell leukemia with jaundice and spontaneous splenic rupture: a case report and review of the literature

Aggressive natural killer cell leukemia/lymphoma (ANKL) is a rare aggressive form of NK-cell neoplasm. We report an uncommon case of 36-year-old male who showed jaundice and spontaneous splenic rupture. The diagnosis was established by the biopsy of liver and spleen. The monomorphous medium-size neoplastic cells infiltrated into portal areas and sinus of liver as well as the...

Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome of Pogostemon cablin (Blanco) Benth

 Xiao-Jun Zhang,1 Hui-Fang Zeng,2 Jian-Nan Chen,1 Yu-Cui Li,1 and Zi-Ren Su1 1School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, China 2The First Hospital

Resiquimod and polyinosinic–polycytidylic acid formulation with aluminum hydroxide as an adjuvant for foot-and-mouth disease vaccine

Background Toll-like receptor (TLR) agonists reportedly have potent antiviral and antitumor activities and may be a new kind of adjuvant for enhancing immune efficacy. Resiquimod (R848) is an imidazoquinoline compound with potent antiviral activity and functions through the TLR7/TLR8 MyD88-dependent signaling pathway. Polyinosinic-polycytidylic acid [poly(I:C)] is a synthetic...

Treatment adherence among sputum smear-positive pulmonary tuberculosis patients in mountainous areas in China

Background We carried out an investigation in five provinces in China to assess treatment adherence and identify factors associated with insufficient treatment adherence in tuberculosis (TB) patients in mountainous, rural areas of China. Methods In each of the five provinces, all counties with > 80% mountainous area were stratified into three groups according to their gross...

The infectivity and pathogenicity of a foot-and-mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010

Background Foot-and mouth disease (FMD) is an acute, febrile, and contagious vesicular disease affecting cloven-hoofed animals. Some animals may become persistent infected carriers when they contact FMD virus (FMDV), and persistent infected animals are a dangerous factor to cause FMD outbreak. Findings 300 OP (oesophageal-pharyngeal) fluid samples were collected from cattle...

Current antibody-based immunoassay algorithm failed to confirm three late-stage AIDS cases in China: case report

2000 , 60 : 43 - 47 . 5. Li Yan , Xu Hui-fang, Han Zhi-gang, Gao Kai, Liang Cai-yun: Sequence analysis of the C2 - V3 region among HIV-1 strains found during 2004- 2005 in Guangzhou . South China J Prev

Functional Evolution of Leptin of Ochotona curzoniae in Adaptive Thermogenesis Driven by Cold Environmental Stress

Background Environmental stress can accelerate the directional selection and evolutionary rate of specific stress-response proteins to bring about new or altered functions, enhancing an organism's fitness to challenging environments. Plateau pika (Ochotona curzoniae), an endemic and keystone species on Qinghai-Tibetan Plateau, is a high hypoxia and low temperature tolerant mammal...