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Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency

Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency Xinyu Bian,* Puyuan Wu,* Huizi Sha, Hanqing Qian, Qing Wang, Lei Cheng

Early urinary angiotensinogen excretion in critically ill neonates

Introduction: Urinary angiotensinogen is considered a reliable biomarker for intrarenal renin–angiotensin system activity. The aims of this study were to assess the urinary angiotensinogen level during the first day of life and to evaluate its correlation with renal function in critically ill neonates.

Alpha-actin-2 mutations in Chinese patients with a non-syndromatic thoracic aortic aneurysm

Background Aortic aneurysms and/or dissection (AADs) in the aorta are a leading cause of human morbidity and mortality. To date, data on non-syndromic thoracic AADs (TAADs) have been mainly derived from Caucasians, and the genetic basis of TAADs remains to be elucidated. In this study, we assessed gene mutations in a Chinese population with TAADs. Methods A cohort of 68 non...

Vitamin C Intake and Pancreatic Cancer Risk: A Meta-Analysis of Published Case-Control and Cohort Studies

Background Observational studies inconsistently reported the relationship between vitamin C intake and risk of pancreatic cancer. We conducted a meta-analysis of published case-control and cohort studies to quantify the association. Methods Potentially eligible studies were found on PubMed and EMBASE databases through May 31, 2015. A random-effects model was assigned to compute...

FSD-C10, a Fasudil derivative, promotes neuroregeneration through indirect and direct mechanisms

design of the study, conducted most of the experiments, analyzed the results, and wrote most of the paper. Bao-guo Xiao and Cun-gen Ma contributed to designing the study. Hai-fei Zhang, Qing Wang and Zhi

Synthesis of Polydopamine Functionalized Reduced Graphene Oxide-Palladium Nanocomposite for Laccase Based Biosensor

Graphene based 2D nanomaterials have attracted increasing attention in biosensing application due to the outstanding physicochemical properties of graphene. In this work, palladium nanoparticles (Pd) loaded reduced graphene oxide (rGO) hybrid (rGO-Pd) was synthesized through a facile method. Laccase (Lac) was immobilized on rGO-Pd by utilizing the self-polymerization of dopamine...

Synthesis of Polydopamine Functionalized Reduced Graphene Oxide-Palladium Nanocomposite for Laccase Based Biosensor

Graphene based 2D nanomaterials have attracted increasing attention in biosensing application due to the outstanding physicochemical properties of graphene. In this work, palladium nanoparticles (Pd) loaded reduced graphene oxide (rGO) hybrid (rGO-Pd) was synthesized through a facile method. Laccase (Lac) was immobilized on rGO-Pd by utilizing the self-polymerization of dopamine...

Robust Synchronization of Hyperchaotic Systems with Uncertainties and External Disturbances

100044, China Received 4 December 2013; Revised 21 March 2014; Accepted 21 March 2014; Published 7 April 2014 Academic Editor: Zlatko Jovanoski Copyright © 2014 Qing Wang et al. This is an open access

A facility location model for socio-environmentally responsible decision-making

Dominic Ansbro 0 Qing Wang 0 0 School of Engineering and Computing Sciences, Durham University , Durham DH1 3LE, UK The consideration of external costs is becoming more important in supply network

An Improved Lumped Parameter Model for a Piezoelectric Energy Harvester in Transverse Vibration

© 2014 Guang-qing Wang and Yue-ming Lu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

An Improved Lumped Parameter Model for a Piezoelectric Energy Harvester in Transverse Vibration

© 2014 Guang-qing Wang and Yue-ming Lu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

The Application of Fluorescence In Situ Hybridization in Different Ploidy Levels Cross-Breeding of Lily

21 crossing were conducted between Asiatic Lily with different ploidy levels, the results showed that the interploidy hybridization between diploid and tetraploid lilies was not as successful as intraploidy hybridization. Regardless of male sterility, triploid lilies could be used as female parents in the hybridization which the progenies were aneuploidy. 3x×4x crosses could be...

Retrospective Study of Phospholipase A2 Receptor and IgG Subclasses in Glomerular Deposits in Chinese Patients with Membranous Nephropathy

Background and objectives The research work in the past years showed that detection of phospholipase A2 receptor (PLA2R) antigen and its dominant IgG4 autoantibody in glomerular deposits of patients with membranous nephropathy (MN) was useful for the differentiation between primary MN (PMN) and secondary MN (SMN), but so far such research data from large Chinese patient series is...

Angiotensin-converting enzyme I/D polymorphism and aortic aneurysm risk: a meta-analysis

OBJECTIVES Angiotensin-converting enzyme (ACE) I/D polymorphism has been implicated in aortic aneurysm risk, but individual published studies show inconclusive results. The aim of this study was to explore a more precise estimation of its relation with aortic aneurysm using meta-analysis.

Monte Carlo Simulation of the Echo Signals from Low-Flying Targets for Airborne Radar

A demonstrated hybrid method based on the combination of half-space physical optics method (PO), graphical-electromagnetic computing (GRECO), and Monte Carlo method on echo signals from low-flying targets based on actual environment for airborne radar is presented in this paper. The half-space physical optics method , combined with the graphical-electromagnetic computing (GRECO...

Monte Carlo Simulation of the Echo Signals from Low-Flying Targets for Airborne Radar

A demonstrated hybrid method based on the combination of half-space physical optics method (PO), graphical-electromagnetic computing (GRECO), and Monte Carlo method on echo signals from low-flying targets based on actual environment for airborne radar is presented in this paper. The half-space physical optics method , combined with the graphical-electromagnetic computing (GRECO...

Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma

Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma Lei Cheng,1,* Zuguang Xia,2,3,* Xinyu Bian,1 Guangchao Li,4 Jing Hu,1 Ya Cao,5 Qing

Proteome Analysis of Poplar Seed Vigor

Seed vigor is a complex property that determines the seed’s potential for rapid uniform emergence and subsequent growth. However, the mechanism for change in seed vigor is poorly understood. The seeds of poplar (Populus × Canadensis Moench), which are short-lived, were stored at 30°C and 75±5% relative humidity for different periods of time (0–90 days) to obtain different vigor...

Factors that influence persistence or recurrence of high-grade squamous intraepithelial lesion with positive margins after the loop electrosurgical excision procedure: a retrospective study

Background In 5–20 % of patients with cervical high-grade squamous intraepithelial lesion (HSIL), a positive margin after the loop electrosurgical excision procedure (LEEP) is associated with persistence/recurrence, but the prognostic value of other clinico-pathological factors is less clear. Methods Among 4336 patients with HSIL who underwent an initial LEEP, 275 (6 %) had HSIL...

Sign Stability for Switched Linear Systems and Its Application in Flight Control

The sign stability concept in ecological systems is introduced into the analysis and synthesis of switched linear system to explore new control design technique. The necessary and sufficient condition for sign stability of a switched linear system under arbitrary switching is achieved via the notion of complete isogenous sign stable set (CISSS). A new approach for the...