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Statistical reporting and table construction guidelines for publication in the Canadian Journal of Anesthesia

binary or continuous variables) are not presented. The uncertainty of effect sizes is not presented with a 95% confidence interval (CI). Information (e.g., weight or height) is presented in either an ... values are reported using too many decimal places. P values are reported in an imprecise manner (P \ 0.05 or P = NS). The specific statistical test(s) that pertain to the primary (and secondary) outcome

Sodium-glucose cotransporter-2 inhibitors (SGLT-2i) in the perioperative setting

for treating type 2 diabetes mellitus (T2DM). Mechanistically, SGLT-2i reduce blood glucose by promoting glucosuria through inhibition of sodiumglucose co-transporter-2 (SGLT-2) channels in the ... are associated with a low risk of hypoglycemia relative to insulin secretory agents.2 In light of their favourable benefit-torisk profile, ease of use (once daily oral administration), and ancillary

Relative importance of strategies for improving the sample size selection and reporting of small randomized clinical trials in anesthesiology

, PhD (&) F. Dexter, MD, PhD , FASA Department of Anesthesia, University of Iowa , 200 Hawkins Drive, 6439 JCP, Iowa City, IA 52242 , USA In the current issue of the Journal, Chow et al.1 report the ... results of a survey of the quality of sample size calculations for two-arm, parallel group, superiority, randomized clinical trials (RCTs) published in six high-impact-factor anesthesiology journals. Trials

Preventing hypotension-induced nausea and vomiting during spinal anesthesia for Cesarean delivery in obese parturients: a small solution for a big problem?

active in this area. In particular, the choice and use of vasopressors is especially controversial. During the last decade and a half, there has been a major shift from the use of ephedrine as the ... shifted from whether we should use alpha agonists to how we should use them. In this issue of the Journal, George et al.5 describe the results of a welldesigned randomized double-blinded trial investigating

Monitoring the brain strikes a discordant note for anesthesiologists

human physiology, especially as it pertains to the cardiovascular and respiratory systems. Perturbations in these systems, however, occur as “collateral damage” with the administration of general ... anesthesia. In contrast, the profound alterations occurring in brain function with general anesthesia are therapeutically indicated. With desirable general anesthesia, there are neurological changes in

Venous circulation and the invisible hand

the supply of goods with demand in market economies, ultimately achieving a state of equilibrium defined by a price that is agreeable to both parties in an economic transaction.1 While the exact meaning ... down complex systems into understandable bits and pieces and simplified rules is prevalent throughout science, including biology. We are taught, for instance, that cardiac output (CO) is equal to the

Anesthesiologists, it’s time to get social!

published via letters to the editor, editorials, blogs, and even tweets, is already a reality in medical publication circles.9 Social media moves post-publication peer review beyond ''letters to the editor ... '' with transparency and real-time author engagement, adding a level of external scrutiny that may identify limitations and ultimately strengthen the science.10 Twitter is increasingly used to enhance

Erratum to: Childhood acute leukemia, maternal beverage intake during pregnancy, and metabolic polymorphisms

. Orsi D. He mon J. Clavel Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Environmental epidemiology of Cancer Group , 16, Avenue Paul Vaillant-Couturier, Batiment 15/16

The Young Investigator Retreat of the Canadian Critical Care Trials Group: mentorship and self-discovery

Division of Critical Care and Institute for Medical Science, University of Toronto , Toronto, ON , Canada 3 J. S. Hutchison, MD Department of Critical Care and Neuroscience and Mental Health Research Program ... , BScPharm, PharmD Department of Pharmacy and Medicine, Sinai Health System , Toronto, ON , Canada The Canadian Critical Care Trials Group (CCCTG) was created in 1989 to improve the care of critically ill

Le commensalisme: un concept fondamental en écologie?

further history of the concept, the paper demonstrates that, while “commensalism” was initially created and used in zoology, it was taken up in other biological disciplines shortly afterward, such as botany ... remained difficult. This, in turn, contributed to the nomadic existence of this concept in the life sciences of the twentieth century. commensalism; ecology; Pierre-Joseph van Beneden; nineteenth century

The impaired anesthesiologist: what you should know about substance abuse

PurposeDespite our considerable experience with the problem of addiction in our specialty, most anesthesia care providers don’t know how to identify or help an impaired colleague. The purpose of this ... on substance use disorder (SUD) to aid in its identification amongst colleagues and to assist in its management. Principal findings Depending on the region, 10-15% of the general population is prone to

Avant-propos/Foreword

science. Articles may be submitted in French or in English. From time to time, the journal will publish thematic issues. This is the case with this issue 37-1, which comprises six articles in number theory ... intend the new Annales to be a high-calibre journal, publishing articles in all areas of pure mathematics, and occasionally in related fields such as applied mathematics, mathematical physics and computer

An update on the prone position: Continuing Professional Development

Purpose The purpose of this Continuing Professional Development module is to provide information needed to prepare for and clinically manage a patient in the prone position. Principal findings Prone ... . We searched MEDLINE and EMBASETM from January 2000 to January 2015 for literature related to the prone position and retrieved only original articles in English. We reviewed the advantages and

Embolie amniotique compliquant une interruption médicale de la grossesse

strongly suspected in the face of the sudden onset of severe arterial hypotension, hypoxic respiratory distress, a coma state and disseminated intravascular coagulopathy immediately after the delivery ... 1. Conclusion Amniotic fluid embolism is a rare and difficult diagnosis, especially in unconventional settings, yet it can be facilitated by screening for amniotic markers and tryptase. Bien que tre