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O-GlcNAcylation, a sweet link to the pathology of diseases

O-linked N-acetylglucosamine (O-GlcNAc) is a dynamic post-translational modification occurring on myriad proteins in the cell nucleus, cytoplasm, and mitochondria. The donor sugar for O-GlcNAcylation, uridine-diphosphate N-acetylglucosamine (UDP-GlcNAc), is synthesized from glucose through the hexosamine biosynthetic pathway (HBP). The recycling of O-GlcNAc on proteins is...

Abstracts from USCAP 2019: Genitourinary Pathology (776-992)

Ridge , IL , USA 28 Erica Vormittag-Nocito 29 The University of Texas MD Anderson Cancer Center , Bellaire, TX , USA - VOLUME 99 | SUPPLEMENT 1 | MARCH 2019 2019 GENITOURINARY PATHOLOGY (INCLUDING RENAL ... . Over the past two decades, tremendous advances have been made in our understanding of the molecular pathology of prostate cancer, although PDA remains relatively understudied. Thus, in this study, we

Abstracts from USCAP 2019: Endocrine Pathology (537-577)

PATHOLOGY A B S T R A C T S E D U C A TI O N C O M MI T T E E J a s o n L. H or ni c k , C h air R h o n d a K. Y a nti s s, C h air, A b str a ct R e vi e w B o ar d a n d A s si g n m e nt C o m mitt e ... pathology practice. Design: To validate the utility of PAX8 as a marker of ATC in a large series, 127 cases of ATC were collected from 5 institutes. Immunostaining of MRQ-50 was performed to detect the

Pathology of the carotid space

The complex anatomy of the carotid space within a small confined area is unique to the head and neck and allows for a vast array of pathology. This paper will review the anatomy of the carotid space ... , thrombus, dissection, pseudoaneurysm, and pathology of the deep cervical chain lymph nodes. Understanding the complex and unique anatomy of the carotid space, as well as the nuances of navigating a broad

7th Congress of the European Society for Analytical Cellular Pathology, Caen, France, 1–5 April 2001

Congress will take you further back into European history. It will be held on 14?21 September 2002 in Crete in partnership with the International Society for Diagnostic Quantitative Pathology. MEDIATORS

Abstracts from USCAP 2019: Infectious Disease Pathology (1435-1462)

- VOLUME 99 | SUPPLEMENT 1 | MARCH 2019 2019 PATHOLOGY INFECTIOUS DISEASE A B S T R A C T S E D U C A TI O N C O M MI T T E E J a s o n L. H or ni c k , C h air R h o n d a K. Y a nti s s, C h air, A b ... pathology and cancer among women. Rania Aly1, Waleed Dawood1, Rasha Elsaka1 1Alexandria University, Alexandria, Egypt Disclosures: Rania Aly: None; Waleed Dawood: None; Rasha Elsaka: None Background

Pathology vs. Economics: Hard Lessons from the Field

or training a sustainable workforce, but one learning curve that is faced regularly is that of the economics of pathology. And they’re not always easy curves to navigate. Incentivizing public ... better cancer care in LMICs. The Dos and Don’ts of Incentives In the world of diagnostic pathology, there have been many iterations of payer systems, but a common concept is that a pathologist gets paid

Thyroglossal duct pathology and mimics

carcinomas are incidentally diagnosed on surgical pathology as the initial disease burden may be microscopic with slow growth. Although thyroglossal duct cysts are anomalies commonly occurring in the pediatric ... image demonstrates FDG avidity in this lesion. Pathology proven papillary carcinoma Mimics of thyroglossal duct cysts There are many mimics of thyroglossal duct cysts, and it is important to recognize

Abstracts from USCAP 2019: Gynecologic and Obstetric Pathology (993-1161)

Cervical Carcinoma? Hussein Alnajar1, Anna-Lee Clarke2, William Watkin3 1University of Chicago (NorthShore) Pathology, Evanston, IL, 2University of Chicago (Evanston-Northshore), Evanston, IL, 3NorthShore ... pathology files.DI, HE and T stage were gleaned from the pathology reports. Slides were reviewed to determine CE, measured by multiplying the number of consecutive slides involved by both 2.5 mm and 3 mm

Abstracts from USCAP 2019: Neuropathology and Ophthalmic Pathology (1621-1666)

- McGill University Ocular Pathology Laboratory & Translational Research Laboratory, Montreal, QC, 2MUHC - McGill University Ocular Pathology Laboratory, Montreal, QC, 3The MUHC - McGill University Ocular ... Pathology & Translational Research Laboratory, Montreal, QC Disclosures: Sabrina Bergeron: None; Miguel Burnier: None Background: In ocular pathology, corneal specimens account for about 13% of all

The elbow: review of anatomy and common collateral ligament complex pathology using MRI

the axial and sagittal images is often advisable to confirm suspected pathology. The normal ligaments appear as homogeneously hypointense structures relative to adjacent skeletal muscle, since they are ... collateral ligament (white asterisks) The introduction of an isotropic three-dimensional (3D) imaging technique (Fig. 2) has shown promise in the visualization of anatomy and pathology of the elbow, as

Development and Validation of a Pathology Image Analysis-based Predictive Model for Lung Adenocarcinoma Prognosis - A Multi-cohort Study

Prediction of disease prognosis is essential for improving cancer patient care. Previously, we have demonstrated the feasibility of using quantitative morphological features of tumor pathology images ... , Dallas, Texas, 75390 , USA 2 Department of Statistics, Southern Methodist University , Dallas, t exas , USA 3 Department of Pathology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical

The diverse neural crest: from embryology to human pathology

cause many of these conditions and, in return, vertebrate embryo models revealed how these genes worked in NC development. Many birth defects are imputable to neural crest pathology The neurocristopathy

Salivary gland carcinoma in Shanghai (2003–2012): an epidemiological study of incidence, site and pathology

.View ArticleGoogle ScholarEllis GL, Auclair PL, Gnepp DR. Surgical pathology of the salivary glands. Major problems in pathology. Vol. 25. Philadelphia: Saunders; 1991.Google ScholarLuukkaa H, Klemi P

LRRK2 modifies α-syn pathology and spread in mouse models and human neurons

(PD). Accruing evidence suggests that α-syn pathology can propagate through neuronal circuits in the brain, contributing to the progressive nature of the disease. Thus, it is therapeutically pertinent ... networks [33]. It has been demonstrated that in human PD brains, α-syn pathology is present in the brainstem and olfactory bulb prior to the onset of motor dysfunction, progressively extending to

Effect of N-Acetyl Cysteine on Intracerebroventricular Colchicine Induced Cognitive Deficits, Beta Amyloid Pathology, and Glial Cells

Among the many factors responsible for the cognitive decline in Alzheimer’s disease, beta amyloid protein and plaque formation is crucial. This amyloid pathology is associated with activation of ... antioxidant effect of NAC on amyloid pathology and cognition and also to investigate the link between amyloid pathology and glial cells activation. Intracerebroventricular colchicine in rats known mimics human

Speech-Language Pathology Students’ Motivation for Learning

The primary purpose of this exploratory study was to attempt to gain a better understanding of speech-language pathology students’ motivations for learning. Motivation was assessed in undergraduate ... Pathology and Audiology Recommended Citation Article 8 Commons Introduction One universal goal of college professors has been to fully understand and enhance students? motivation for learning. Motivation