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Search: authors:"A. Miyazaki"

7 papers found.
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Semantic integration of gene expression analysis tools and data sources using software connectors

Background The study and analysis of gene expression measurements is the primary focus of functional genomics. Once expression data is available, biologists are faced with the task of extracting (new) knowledge associated to the underlying biological phenomenon. Most often, in order to perform this task, biologists execute a number of analysis activities on the available gene...

First millimeter-wave spectroscopy of ground-state positronium

We report on the first measurement of the Breit–Wigner resonance of the transition from ortho-positronium to para-positronium. We have developed an optical system to accumulate a power of over 20 kW using a frequency-tunable gyrotron and a Fabry–Pérot cavity. This system opens a new era of millimeter-wave spectroscopy, and enables us to directly determine both the hyperfine...

Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice

Aims/hypothesis Several lines of evidence suggest that incretin-based therapies suppress the development of cardiovascular disease in type 2 diabetes. We investigated the possibility that glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) can prevent the development of atherosclerosis in Apoe −/− mice. Methods Apoe −/− mice (17 weeks old) were...

Recurrent Pyogenic Vertebral Osteomyelitis Associated with Type 2 Diabetes Mellitus

We report a case of recurrent pyogenic vertebral osteomyelitis associated with type 2 diabetes mellitus. A 51-year-old male was admitted to our hospital because of lumbago and general fatigue, with multiple ulcers on the soles of his feet. Staphylococcus aureus was isolated from peripheral blood and the foot ulcers, and 67Gallium scintigram showed abnormal isotope uptake...

Aspartic acid at position 57 of DQβ chain does not protect against Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects

SummaryHLA DQβ chain, in particular amino acid at position 57, has been reported to contribute to susceptibility and resistance to Type 1 (insulin-dependent) diabetes mellitus in Caucasians. Resistance has been proposed to be conferred by aspartic acid at this position. To ascertain the association of HLA DQβ and DRβ genes with Type 1 diabetes in Japanese subjects, ten Japanese...