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Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria

Background. This study sought to identify the pattern of electrocardiographic changes in steady state adult sickle cell anaemia. Methods. A case-control, cross-sectional study was conducted amongst sickle cell patients attending the sickle cell clinic of Lagos State University Teaching Hospital, Ikeja, and HbAA controls. All consenting participants had haemoglobin electrophoresis...

Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria

Background. This study sought to identify the pattern of electrocardiographic changes in steady state adult sickle cell anaemia. Methods. A case-control, cross-sectional study was conducted amongst sickle cell patients attending the sickle cell clinic of Lagos State University Teaching Hospital, Ikeja, and HbAA controls. All consenting participants had haemoglobin electrophoresis...

Awareness, Knowledge, and Acceptance of Haematopoietic Stem Cell Transplantation for Sickle Cell Anaemia in Nigeria

State, Nigeria Received 4 May 2016; Revised 1 July 2016; Accepted 11 August 2016 Academic Editor: Eva C. Guinan Copyright © 2016 Adewumi Adediran et al. This is an open access article distributed ... the various treatment modalities for sickle cell anaemia. Competing Interests The authors report no conflict of interests in this work. Authors’ Contributions Adewumi Adediran performed

Awareness, Knowledge, and Acceptance of Haematopoietic Stem Cell Transplantation for Sickle Cell Anaemia in Nigeria

State, Nigeria Received 4 May 2016; Revised 1 July 2016; Accepted 11 August 2016 Academic Editor: Eva C. Guinan Copyright © 2016 Adewumi Adediran et al. This is an open access article distributed ... the various treatment modalities for sickle cell anaemia. Competing Interests The authors report no conflict of interests in this work. Authors’ Contributions Adewumi Adediran performed

Impact of HIV Infection and Zidovudine Therapy on RBC Parameters and Urine Methylmalonic Acid Levels

; Revised 5 January 2016; Accepted 13 January 2016 Academic Editor: Sandro Cinti Copyright © 2016 Adewumi Adediran et al. This is an open access article distributed under the Creative Commons Attribution ... . Authors’ Contribution Adewumi Adediran performed conceptualization, study design, study supervision, and paper write-up. Vincent Osunkalu contributed to study design, data analysis, and paper review

Factors influencing CD4 cell count in HIV-positive pregnant women in a secondary health center in Lagos, Nigeria

O Dosunmu,1 Adewumi Adediran,4 Adekunle Sobande2 1Department of Haematology and Blood Transfusion, 2Department Of Obstetrics and Gynaecology, College of Medicine, Lagos State University, Ikeja, Lagos

Seroprevalence of human T-lymphotropic virus antibodies among patients with lymphoid malignancies at a tertiary center in Lagos, Nigeria

Sarah John-Olabode,3 Adewumi Adediran,4 Olajumoke Oshinaike,5 Ebele Uche,1 Akinola Dada,5 Mojeed Odesanya,6 Olaitan Okunoye7 1Department of Haematology and Blood Transfusion, College of Medicine, Lagos ... scientific and medical research O r i g i n a l r e s e a r c h akinsegun akinbami 1 idris Durojaiye 2 adedoyin Dosunmu 1 sarah John-Olabode 3 adewumi adediran 4 Olajumoke Oshinaike5 ebele Uche1 akinola Dada

Haematological values in homozygous sickle cell disease in steady state and haemoglobin phenotypes AA controls in Lagos, Nigeria

Background Sickle cell disease is a genetic abnormality involving the haemoglobin. Although, it is primarily a red cell disorders, the white blood cells and platelets are also affected by the mutation. The consequent haemoglobin S causes polymerization of haemoglobin resulting in haemolysis and anaemia. This study aims to provide baseline haematological values in sickle cell...

The Kikuchi-Fujimoto Disease in Nigeria: A Case Report and Literature Review

The Kikuchi-Fujimoto is a rare, self-limiting disease, which is characterized by regional lymphadenopathy. It occurs worldwide with a higher prevalence among Asians and women below the age of forty years. We present 41-year-old Nigerian woman who was investigated extensively for unilateral left cervical lymphadenopathy. She was eventually diagnosed as having the Kikuchi-Fujimoto...

The Kikuchi-Fujimoto Disease in Nigeria: A Case Report and Literature Review

The Kikuchi-Fujimoto is a rare, self-limiting disease, which is characterized by regional lymphadenopathy. It occurs worldwide with a higher prevalence among Asians and women below the age of forty years. We present 41-year-old Nigerian woman who was investigated extensively for unilateral left cervical lymphadenopathy. She was eventually diagnosed as having the Kikuchi-Fujimoto...

CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria

Background. CD4 count measures the degree of immunosuppression in HIV-positive patients. It is also used in deciding when to commence therapy, in staging the disease, and in determining treatment failure. Using the CD4 count, this study aimed at determining the percentage of HIV-positives who require antiretroviral therapy at enrollment in an HIV treatment and care centre...

The relationship between red blood cell distribution width and blood pressure in patients with type 2 diabetes mellitus in Lagos, Nigeria

Majeed Odesanya,3 Sarah John-Olabode,4 Adewumi Adediran,5 Olajumoke Oshinaike,1 Anthonia Okeoghene Ogbera,1 Olaitan Okunoye,6 Olanrewaju Arogundade,2 Kingsley Aile,7 Timothy Ekwere8 1Department of Medicine

Prevalence of Priapism and Its Awareness amongst Male Homozygous Sickle Cell Patients in Lagos, Nigeria

; Revised 1 June 2013; Accepted 13 June 2013 Academic Editor: Nazareno Suardi Copyright © 2013 Adewumi Adediran et al. This is an open access article distributed under the Creative Commons Attribution

Prevalence of Priapism and Its Awareness amongst Male Homozygous Sickle Cell Patients in Lagos, Nigeria

; Revised 1 June 2013; Accepted 13 June 2013 Academic Editor: Nazareno Suardi Copyright © 2013 Adewumi Adediran et al. This is an open access article distributed under the Creative Commons Attribution

Seroprevalence of hepatitis B e antigen (HBe antigen) and B core antibodies (IgG anti-HBcore and IgM anti-HBcore) among hepatitis B surface antigen positive blood donors at a Tertiary Centre in Nigeria

Background Hepatitis B virus (HBV) is a common cause of liver disease throughout the world. HBV is transmitted through blood and other body fluids, including semen and saliva. Chronic replication of HBV virons is characterized by persistence circulation of HBsAg, HBeAg and HBV DNA; usually with anti-HBc and occasionally with anti-HBs. Aim: To determine the prevalence of HBeAg...

Serum testosterone levels of HbSS (sickle cell disease) male subjects in Lagos, Nigeria

Background Infertility is a major problem in sickle cell disease patients, especially in males. In addition to low serum testosterone, other abnormalities involving the accessory sex organs, such as the seminal vesicles and the prostate gland, as well as marked decrease in ejaculate volume may be observed in male HbSS patients. Hence, the need to study the role of sex hormones as...

Seroprevalence of hepatitis B e antigen (HBe antigen) and B core antibodies (IgG anti-HBcore and IgM anti-HBcore) among hepatitis B surface antigen positive blood donors at a Tertiary Centre in Nigeria

Hepatitis B virus (HBV) is a common cause of liver disease throughout the world. HBV is transmitted through blood and other body fluids, including semen and saliva. Chronic replication of HBV virons is characterized by persistence circulation of HBsAg, HBeAg and HBV DNA; usually with anti-HBc and occasionally with anti-HBs. Aim: To determine the prevalence of HBeAg, IgG anti...

Seroprevalence of cytomegalovirus antibodies amongst normal pregnant women in Nigeria

Seroprevalence of cytomegalovirus antibodies amongst normal pregnant women in Nigeria Akinsegun Abduljaleel Akinbami1, Kabiru Afolarin Rabiu2, Adeniyi Abiodun Adewunmi2, Kikelomo Ololade Wright3, Adedoyin Owolabi Dosunmu1, Titilope Adenike Adeyemo4, Adewumi Adediran4, Oluseye Vincent Osunkalu41Department of Haematology and Blood Transfusion, 2Department of Obstetrics and...