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11 papers found.
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Australian shellfish ecosystems: Past distribution, current status and future direction

, Colin Creighton, Ben Diggles, John Ford, Paul Hamer, Kylie Russell. Data curation: Chris L. Gillies, Ian M. McLeod, Ben Diggles, Paul Hamer, Emma Lebrault, Agnès Le Port, Kylie Russell, Bryn Warnock ... . Formal analysis: Chris L. Gillies, Ian M. McLeod, Heidi K. Alleway, Peter Cook, Christine Crawford, Colin Creighton, Ben Diggles, John Ford, Paul Hamer, Gideon Heller-Wagner, Emma Lebrault, Agnès Le Port

Importance of Adequate Local Spatiotemporal Transmission Measures in Malaria Cohort Studies: Application to the Relation Between Placental Malaria and First Malaria Infection in Infants

According to several studies, infants whose mothers had a malaria-infected placenta (MIP) at delivery are at increased risk of a first malaria infection. Immune tolerance caused by intrauterine contact with the parasite could explain this phenomenon, but it is also known that infants who are highly exposed to Anopheles mosquitoes infected with Plasmodium are at greater risk of...

Maternal Anaemia at Delivery and Haemoglobin Evolution in Children during Their First 18 Months of Life Using Latent Class Analysis

Background Anaemia during pregnancy and at delivery is an important public health problem in low- and middle-income countries. Its association with the children’s haemoglobin level over time remains unclear. Our goals were to identify distinct haemoglobin level trajectories using latent class analysis and to assess the association between these trajectories and maternal anaemia...

Placental Malaria is Associated With Increased Risk of Nonmalaria Infection During the First 18 Months of Life in a Beninese Population

Background. Several studies have shown that the risk of malaria infection increases for children born to a mother with placental malaria infection. An immune tolerance phenomenon has been hypothesized. We addressed whether Plasmodium falciparum placental infection could additionally be associated with the risk of nonmalaria fevers in infants. Methods. From 2007 to 2009, 553...

Association between Dietary Patterns and Depressive Symptoms Over Time: A 10-Year Follow-Up Study of the GAZEL Cohort

Background Data on the association between dietary patterns and depression are scarce. The objective of this study was to examine the longitudinal association between dietary patterns and depressive symptoms assessed repeatedly over 10 years in the French occupational GAZEL cohort. Methods A total of 9,272 men and 3,132 women, aged 45–60 years in 1998, completed a 35-item Food...

Modeling the Influence of Local Environmental Factors on Malaria Transmission in Benin and Its Implications for Cohort Study

Malaria remains endemic in tropical areas, especially in Africa. For the evaluation of new tools and to further our understanding of host-parasite interactions, knowing the environmental risk of transmission—even at a very local scale—is essential. The aim of this study was to assess how malaria transmission is influenced and can be predicted by local climatic and environmental...

Association of IL-4 and IL-10 maternal haplotypes with immune responses to P. falciparum in mothers and newborns

Background Particular cytokine gene polymorphisms are involved in the regulation of the antibody production. The consequences of already described IL-4, IL-10 and IL-13 gene polymorphisms on biological parameters and antibody levels were investigated among 576 mothers at delivery and their newborns in the context of P. falciparum placental malaria infection. Methods The study...

Relation between Plasmodium falciparum asymptomatic infection and malaria attacks in a cohort of Senegalese children

Background It is important to establish whether or not the presence of malaria parasites in peripheral blood of asymptomatic individuals is a predictor of future clinical mild malaria attacks (MMA). The aim of this study was to determine how an asymptomatic positive thick blood smear could be related to the occurrence of a MMA during the nine following days. Methods The study was...

Mass Spectrometry Detection of G3m and IGHG3 Alleles and Follow-Up of Differential Mother and Neonate IgG3

Mass spectrometry (MS) analysis for detection of immunoglobulins (IG) of the human IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. IgG3 is the most polymorphic human IgG subclass with thirteen G3m allotypes located on the constant CH2 and CH3 domains of the gamma3 chain, the combination of which leads to six major G3m alleles. Amino...

Infections in Infants during the First 12 Months of Life: Role of Placental Malaria and Environmental Factors

Background The association between placental malaria (PM) and first peripheral parasitaemias in early infancy was assessed in Tori Bossito, a rural area of Benin with a careful attention on transmission factors at an individual level. Methodology Statistical analysis was performed on 550 infants followed weekly from birth to 12 months. Malaria transmission was assessed by...