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Cognitive status in patients with multiple sclerosis in Lanzarote

Cognitive status in patients with multiple sclerosis in Lanzarote María Yaiza Pérez-Martín,1 Pablo Eguia-del Río,2 Montserrat González-Platas,1 Alejandro Jiménez-Sosa31Service of Neurology, Complejo ... Neuropsychiatric Disease and Treatment cognitive status in patients with multiple sclerosis in lanzarote María Yaiza Pérez-Martín Pablo eguia-del río 2 Montserrat gonzález-Platas 1 alejandro

DIFFERENT BRAIN STRUCTURES EXHIBIT THE SAME CAFFEINE LEVELS AFTER THE ADMINISTRATION OF A SINGLE DOSE OF CAFFEINE

MUESTRAN CONCENTRACIÓN DE CAFEÍNA SIMILAR DESPUÉS DE LA ADMINISTRACIÓN DE UNA DOSIS ÚNICA Mary Orrego Cardozo1 Alejandro Jiménez-Rodriguez2 Alejandro Osorio-Forero3 Francia Restrepo4 Juan Miguel

Association between total antioxidant capacity and mortality in ischemic stroke patients

‑González 6 Luis Ramos 5 Mónica Argueso 4 Juan J. Cáceres 3 Jordi SoléV‑iolán 8 Alejandro Jiménez 7 0 Intensive Care Unit, Hospital Universitario de Canarias , Ofra, s/n, 38320 La Laguna, Santa Cruz de

Serum caspase-3 levels and mortality are associated in patients with severe traumatic brain injury

Jordi Solé-Violán 5 Marta Riaño-Ruiz 4 Alejandro Jiménez 3 Juan M. Borreguero-León 7 0 Intensive Care Unit, Hospital Universitario de Canarias , Ofra, s/n. La Laguna, 38320 Santa Cruz de Tenerife , Spain

Serum caspase-3 levels and mortality are associated in patients with severe traumatic brain injury

Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TBI patients between serum caspase-3 levels (thus using an easier, quicker...

El suicidio y su tendencia social en México: 1990-2011

cifras presentadas son proyecciones presentadas en cuadernillos del INEGI   Información sobre los autores: René Alejandro Jiménez Órnelas. Es actuario por la Facultad de Ciencias de la Universidad

Geometry and Proportions in the Funeral Chapel of Sarenput II

This paper analyzes the geometry and proportions of the funeral chapel of Sarenput II, built some 4,000 years ago in the necropolis of Qubbet el-Hawa in Egypt. The analysis is done with the utmost respect for ancient sources, and in particular for Egyptian mathematical knowledge. In a first general analysis, the different parts that make up the chapel are analysed in terms of...

Total antioxidant capacity is associated with mortality of patients with severe traumatic brain injury

-González 6 Luis Ramos 5 Mónica Argueso 4 Marta Riaño-Ruiz 3 Jordi Solé-Violán 8 Alejandro Jiménez 7 0 Intensive Care Unit, Hospital Universitario de Canarias , Ofra, s/n. La Laguna, 38320 Santa Cruz de

Serum Malondialdehyde Levels in Patients with Malignant Middle Cerebral Artery Infarction Are Associated with Mortality

Objective Malondialdehyde (MDA) is an end-product formed during lipid peroxidation, due to degradation of cellular membrane phospholipids. MDA is released into extracellular space and finally into the blood; it has been used as an effective biomarker of lipid oxidation. High circulating levels of MDA have been previously described in patients with ischemic stoke than in controls...

The 4G/4G Genotype of PAI-1 Polymorphism Is Associated with Higher Plasma PAI-1 Concentrations and Mortality in Patients with Severe Sepsis

Objective Two studies have reported that patients with the 4G/4G genotype of the plasminogen activator inhibitor-1 (PAI-1) genetic polymorphism had higher plasma PAI-1 concentrations and higher risk of death than those with the 4G/5G or 5G/5G genotypes; one study involved 175 children with meningococcal disease, and the other included 88 adult patients with septic shock. Thus...

Serum substance P levels are associated with severity and mortality in patients with severe traumatic brain injury

Introduction Substance P (SP) is a member of the tachykinin family of neuropeptides, which are widely distributed throughout the central nervous system (CNS) and actively involved in inflammatory processes. SP is released early following acute injury to the CNS, promoting a neurogenic inflammatory response characterized by an increase in the permeability of the blood–brain...

Continuous endotracheal tube cuff pressure control system protects against ventilator-associated pneumonia

Introduction The use of a system for continuous control of endotracheal tube cuff pressure reduced the incidence of ventilator-associated pneumonia (VAP) in one randomized controlled trial (RCT) with 112 patients but not in another RCT with 142 patients. In several guidelines on the prevention of VAP, the use of a system for continuous or intermittent control of endotracheal cuff...

Serum Levels of Caspase-Cleaved Cytokeratin-18 in Patients with Severe Traumatic Brain Injury Are Associated with Mortality: A Pilot Study

Objective There have been found apoptotic changes in brain tissue samples from animals and humans after a traumatic brain injury (TBI). The protein cytokeratin 18 (CK-18), present in epithelial cells, is cleaved by the action of caspases during apoptosis, and the resulting fragments are released into the blood as caspase-cleaved CK (CCCK)-18. Circulating levels of CCCK-18, as...

Serum Levels of Caspase-Cleaved Cytokeratin-18 and Mortality Are Associated in Severe Septic Patients: Pilot Study

Objective Apoptosis is increased in sepsis. Cytokeratin 18 (CK-18), a protein of the intermediate filament group present in most epithelial and parenchymal cells, is cleaved by the action of caspases and released into the blood as caspase-cleaved CK (CCCK)-18 during apoptosis. Circulating levels of CCCK-18 have scarcely been explored in septic patients. In one study with 101...

Effect of binge eating disorder on the outcomes of laparoscopic gastric bypass in the treatment of morbid obesity

gástrico laparóscopico en el tratamiento de la obesidad mórbida     Eduardo García Díaz1, María Elena Jerez Arzola2, Tomás Martín Folgueras2, Luis Morcillo Herrera2 and Alejandro Jiménez Sosa3

Red Blood Cell Distribution Width during the First Week Is Associated with Severity and Mortality in Septic Patients

Objective Higher values of red blood cell distribution width (RDW) have been found in non-surviving than in surviving septic patients. However, it is unknown whether RDW during the first week of sepsis evolution is associated with sepsis severity and early mortality, oxidative stress and inflammation states, and these were the aims of the study. Methods We performed a prospective...

Higher platelet cytochrome oxidase specific activity in surviving than in non-surviving septic patients

Introduction In a previous study with 96 septic patients, we found that circulating platelets in 6-months surviving septic patients showed higher activity and quantity of cytochrome c oxidase (COX) normalized by citrate synthase (CS) activity at moment of severe sepsis diagnosis than non-surviving septic patients. The objective of this study was to estimate whether COX specific...

Anomalía de Ebstein

Eduardo Juárez-Orozco,**** Alejandro Jiménez-Niño,*** Sebastián Álvarez,*** Erick Alexánderson-Rosas**   * Facultad Mexicana de Medicina. Universidad La Salle. ** Departamento de Cardiología Nuclear

Association of Sepsis-Related Mortality with Early Increase of TIMP-1/MMP-9 Ratio

Objective Higher circulating levels of tissue inhibitor of matrix metalloproteinases (TIMP)-1 at the time of severe sepsis diagnosis have been reported in nonsurviving than in surviving patients. However, the following questions remain unanswered: 1) Does TIMP-1/MMP-9 ratio differ throughout the first week of intensive care between surviving and non-surviving patients? 2) Is...