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Diagnose und Management der Osteoporose bei Diabetes mellitus (Update 2019)

ZusammenfassungDiabetes mellitus und Osteoporose zählen zu den häufigsten chronischen Erkrankungen und kommen deshalb beide häufig in ein und demselben Individuum vor. Da die Prävalenz beider mit steigendem Alter zunimmt, wird in Anbetracht der Altersstruktur unserer Bevölkerung deren Häufigkeit zunehmen.Patienten mit Diabetes haben ein erhöhtes Risiko für Fragilitätsfrakturen...

Geschlechtsspezifische Aspekte bei Prädiabetes und Diabetes mellitus – klinische Empfehlungen (Update 2019)

ZusammenfassungMetabolische Erkrankungen beeinflussen das Leben von Männern und Frauen in den verschiedenen Lebensabschnitten in unterschiedlicher und vielfältiger Weise und stellen eine große Herausforderung für das Gesundheitssystem dar. Die behandelnden Ärztinnen und Ärzte sind mit den unterschiedlichen Bedürfnissen von Männern und Frauen im klinischen Alltag konfrontiert...

Ernährungsempfehlungen bei Diabetes mellitus (Update 2019)

ZusammenfassungEs besteht breiter Konsens, dass eine effiziente Diabetes-Therapie in den meisten Fällen auch von einer Modifikation des Lebensstils begleitet sein muss. Das bedeutet für die Patienten in der Regel eine Normalisierung des Körpergewichts (Gewichtsreduktion und/oder Halten des Gewichts) in Kombination mit einer Veränderung des Bewegungs- und Ernährungsverhaltens.Die...

Gestationsdiabetes (GDM) (Update 2019)

ZusammenfassungGestationsdiabetes (GDM) wird als Glukosetoleranzstörung definiert, die erstmals in der Schwangerschaft entdeckt wird. GDM ist mit einer erhöhten fetomaternalen Morbidität sowie Langzeitkomplikationen bei Mutter und Kind assoziiert. Frauen, die die Kriterien eines manifesten Diabetes bereits in der Frühschwangerschaft erfüllen (Nüchternplasmaglukose >126 mg/dl...

Diabetische Nierenerkrankung (Update 2019)

ZusammenfassungRezente epidemiologische Untersuchungen zeigen, dass etwa 2–3 % aller Österreicher Diabetes mit Nierenbeteiligung aufweisen. Diese betrifft somit in Österreich etwa 250.000 Menschen. Das Risiko des Auftretens und Fortschreitens der Erkrankung kann durch Lebensstilinterventionen und Optimierung der Einstellung des Blutdrucks, Blutzuckers und spezielle...

Adiponectin and Leptin at Early Pregnancy: Association to Actual Glucose Disposal and Risk for GDM—A Prospective Cohort Study

Alexandra Kautzky-Willer conceived the study. Data assessment and patient recruitment were performed by Latife Bozkurt and Christian S. G?bl. Statistical analysis, calculations, and data interpretation were ... performed by Christian S. G?bl and Latife Bozkurt. The manuscript was written by Latife Bozkurt. Christian S. G?bl, Anton Luger, Giovanni Pacini, Sabina Baumgartner-Parzer, and Alexandra Kautzky-Willer

Pericardial Fat Relates to Disturbances of Glucose Metabolism in Women with the Polycystic Ovary Syndrome, but Not in Healthy Control Subjects

Correspondence should be addressed to Alexandra Kautzky-Willer; ta.ca.neiwinudem@relliw-ykztuak.ardnaxela Received 17 December 2017; Revised 26 February 2018; Accepted 4 July 2018; Published 7 August 2018 ... Leutner did the statistical analysis and wrote the manuscript. Christian Göbl, Peter Wolf, Katharina Maruszczak, Johannes Ott, Christian Egarter, Siegfried Trattnig, and Alexandra Kautzky-Willer reviewed

Antihyperglykämische Therapie bei Diabetes mellitus Typ 2 (Update 2019)

Sharp & Dohme, Novartis, Novo Nordisk, Roche, sanofi-aventis, Servier, Takeda. Alexandra Kautzky-Willer hat von folgenden Unternehmen, die auch fördernde Mitglieder der ÖDG sind, Forschungsunterstützungen

Management of Pregnant Women after Bariatric Surgery

Bernhard Ludvik,2,5 Anton Luger,2 Alexandra Kautzky-Willer,1 and Michael Krebs2 1Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, Vienna ... , Krankenanstalt Rudolfstiftung, Vienna, Austria Correspondence should be addressed to Alexandra Kautzky-Willer; ta.ca.neiwinudem@relliw-ykztuak.ardnaxela Received 22 November 2017; Accepted 29 April 2018

Type 2 Diabetes and Cardiovascular Risk in Women 2016

, Italy 6Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy Correspondence should be addressed to Alexandra Kautzky-Willer; ta.ca.neiwinudem@relliw-ykztuak.ardnaxela ... Received 6 March 2017; Accepted 6 March 2017; Published 4 July 2017 Copyright © 2017 Alexandra Kautzky-Willer et al. This is an open access article distributed under the Creative Commons Attribution

Type 2 Diabetes and Cardiovascular Risk in Women 2016

, Italy 6Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy Correspondence should be addressed to Alexandra Kautzky-Willer; ta.ca.neiwinudem@relliw-ykztuak.ardnaxela ... Received 6 March 2017; Accepted 6 March 2017; Published 4 July 2017 Copyright © 2017 Alexandra Kautzky-Willer et al. This is an open access article distributed under the Creative Commons Attribution

Brennpunkt Adipositas: what gender has to do with …!

SummaryObesity is increasing worldwide in both sexes and a challenge for health professionals and the health care system. Women have more subcutaneous fat and are more insulin sensitive while men have more visceral and liver fat and higher cardiovascular risk. Women more often show the metabolically healthy obese phenotype than males. However, with increasing BMI the risk for...

Assessment of glucose regulation in pregnancy after gastric bypass surgery

Aims/hypothesis Roux-en-Y gastric bypass (RYGB) surgery is characterised by glycaemic variability. Prospective studies of glucose metabolism in pregnancy after RYGB are not available, therefore this study aimed to evaluate physiological alterations in glucose metabolism in pregnancy following RYGB. Methods Sixty-three pregnant women (25 who underwent RYGB, 19 non-operated obese...

Switch to Combined GLP1 Receptor Agonist Lixisenatide with Basal Insulin Glargine in Poorly Controlled T2DM Patients with Premixed Insulin Therapy: A Clinical Observation and Pilot Study in Nine Patients

Nordisk, Lilly, and Sanofi. Peter Wolf, Lana Kosi-Trebotic, Albert Lukas, Yvonne Winhofer, Alexandra Kautzky-Willer, and Ju¨ rgen Harreiter have no conflicts of interest. Compliance with Ethics Guidelines

The impact of preconceptional obesity on trajectories of maternal lipids during gestation

Growing challenges of maternal obesity necessitate to focus metabolic management on alternative factors than glycaemia. The objective is to assess longitudinal changes in lipids and inflammatory parameters during pregnancies stratified by pregestational BMI. Therefore, 222 pregnant women (normal-weight BMI < 25: n = 91 (41%), overweight BMI 25–29.9: n = 69 (31%), obese BMI ≥ 30...

Similarities in trabecular hypertrophy with site-specific differences in cortical morphology between men and women with type 2 diabetes mellitus

The goal of our study was to investigate interactions between sex and type 2 diabetes mellitus (T2DM) with regard to morphology of the peripheral skeleton. We recruited 85 subjects (mean age, 57±11.4 years): women with and without T2DM (n = 17; n = 16); and men with and without T2DM (n = 26; n = 26). All patients underwent high-resolution, peripheral, quantitative, computed...

Altered glucose profiles and risk for hypoglycaemia during oral glucose tolerance testing in pregnancies after gastric bypass surgery

Aims/hypothesis A history of gastric bypass surgery can influence the results of the OGTT recommended during pregnancy. Therefore, we compared OGTT glucose kinetics and pregnancy outcome between pregnant gastric bypass patients and BMI-matched, lean and obese controls. Methods Medical records were used to collect data on glucose measurements during the 2 h 75 g OGTT as well as on...

Application of Penalized Regression Techniques in Modelling Insulin Sensitivity by Correlated Metabolic Parameters

This paper aims to introduce penalized estimation techniques in clinical investigations of diabetes, as well as to assess their possible advantages and limitations. Data from a previous study was used to carry out the simulations to assess: a) which procedure results in the lowest prediction error of the final model in the setting of a large number of predictor variables with...

Cardiometabolic Risk in Hyperlipidemic Men and Women

Objective. The aim of this study was to evaluate sex specific differences of metabolic and clinical characteristics of treated hyperlipidemic men and women (HL-men and HL-women). Methods. In this study vascular and metabolic characteristics of 35 HL-women and 64 HL-men were assessed. In addition a sex specific analysis of metabolic and nutritional habits of HL-patients with...