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Ependymal cilia beating induces an actin network to protect centrioles against shear stress

Multiciliated ependymal cells line all brain cavities. The beating of their motile cilia contributes to the flow of cerebrospinal fluid, which is required for brain homoeostasis and functions. Motile cilia, nucleated from centrioles, persist once formed and withstand the forces produced by the external fluid flow and by their own cilia beating. Here, we show that a dense actin...

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia

Spassky 0 1 2 0 Boris Guirao , Alice Meunier, Ste?phane Mortaud, Andrea Aguilar, Jean-Marc Corsi, Laetitia Strehl, Yuki Hirota, Ange?lique Desoeuvre, Camille Boutin, Young-Goo Han, Zaman Mirzadeh, Harold