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Ürik Asidin Antioksidan ve Pro-Oksidan Özellikleri ile İlgili Kavram ve Tartışmalarının Derlemesi

Ürik asit, insanlarda pürin metabolizmasının son ürünüdür, gutta kristallerinin yoğun olarak (>7 mg/dl) biriktiği bilinmektedir. İnsanlarda, yüksek konsantrasyonda ürik asitin evrimsel bir avantaj  olduğu düşünülmektedir.Aynı zamanda, insanlarda yüksek ürik asit konsantrasyonunun; evrim  sürecinde kaybolan askorbik asitin antioksidan kapasitesini telafi ettiği hipotezi ortaya at...

Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites

Prakash Chandra Mishra 0 Anuj Kumar 0 Amit Sharma 0 0 Address: Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology Aruna Asaf Ali Road , New

Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli

; Revised 21 November 2015; Accepted 25 November 2015 Academic Editor: J. Justin Hsuan Copyright © 2015 Anuj Kumar Gupta et al. This is an open access article distributed under the Creative Commons

Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli

Aberrant glycosylation is one of the major hallmarks of cancer with altered gene expression signatures of sialyltransferases. ST3Gal-I, a sialyltransferase, is known to play a crucial role in sialylation of T antigen in bladder cancer and it has reported elevated expression in breast carcinogenesis with increased tumor progression stages. The aim of the current study is to...

Influence of alumina/MWCNT hybrid nanoparticle additives on tribological properties of lubricants in turning operations

27.36%, respectively, as compared to alumina-based lubricants. hybrids; nanolubricants; MQL; MWCNT; tool wear; friction coefficient - Anuj Kumar SHARMA*, Jitendra Kumar KATIYAR, Shubrajit BHAUMIK ... , provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Anuj Kumar SHARMA. He received his PhD

Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains

Anuj Kumar Gupta,2 Madhvi Ahuja,1 Vinay Pathak,1 Utpal Sengupta,1 1Stanley Browne Laboratory, The Leprosy Mission Trust India, TLM Community Hospital Nand Nagari, 2Agilent Technologies India Pvt Ltd

Industrial enzymes in bioindustrial sector development: An Indian perspective

, Canada, India and Malaysia 1 Anuj Kumar Chandel has an MSc and is currently pursuing a PhD in biotechnology at the Jawaharlal Nehru Technological University. He is also working with Celestial Labs Ltd

Characterization of W p -type of spaces involving fractional Fourier transform

The characterizations of W p -type of spaces and mapping relations between W- and W p -type of spaces are discussed by using the fractional Fourier transform. The uniqueness of the Cauchy problems is also investigated by using the same transform. MSC: 46F12, 46E15.

Phylogenetic and Preliminary Phenotypic Analysis of Yeast PAQR Receptors: Potential Antifungal Targets

Proteins belonging to the Progestin and AdipoQ Receptor (PAQR) superfamily of membrane bound receptors are ubiquitously found in fungi. Nearly, all fungi possess two evolutionarily distinct paralogs of PAQR protein, which we have called the PQRA and PQRB subtypes. In the model fungus Saccharomyces cerevisiae, these subtypes are represented by the Izh2p and Izh3p proteins...

Structure, localization and histone binding properties of nuclear-associated nucleosome assembly protein from Plasmodium falciparum

Background Nucleosome assembly proteins (NAPs) are histone chaperones that are crucial for the shuttling and incorporation of histones into nucleosomes. NAPs participate in the assembly and disassembly of nucleosomes thus contributing to chromatin structure organization. The human malaria parasite Plasmodium falciparum contains two nucleosome assembly proteins termed PfNapL and...

Complex dynamic of plankton–fish interaction with quadratic harvesting and time delay

The present paper deals with a food chain model consisting of three species phytoplankton, zooplankton and fish. We have divided the present paper into two parts. In the first part, we have assumed that the fish population is harvested using a non-linear harvesting function. Considering this rate of harvesting ‘E’ as a control parameter, we have estimated different ranges of...

The effect of an external toxicant on a biological species in case of deformity: a model

Classification 34 C60 92D25 93A30 4 & Anuj Kumar Agarwal In this paper, a mathematical model is proposed and analyzed to study the effect of an external toxicant on a biological species. Here, we have considered

TEAK: Topology Enrichment Analysis frameworK for detecting activated biological subpathways

To mine gene expression data sets effectively, analysis frameworks need to incorporate methods that identify intergenic relationships within enriched biologically relevant subpathways. For this purpose, we developed the Topology Enrichment Analysis frameworK (TEAK). TEAK employs a novel in-house algorithm and a tailor-made Clique Percolation Method to extract linear and nonlinear...

Organelle DB: an updated resource of eukaryotic protein localization and function

Organelle DB (http://organelledb.lsi.umich.edu) is a web-accessible relational database presenting a supplemented catalog of organelle-localized proteins and major protein complexes. Since its release in 2004, Organelle DB has grown by 20% to encompass over 30 000 proteins from 138 eukaryotic organisms. Each protein in Organelle DB is presented with its subcellular localization...

Genomic analysis of insertion behavior and target specificity of mini-Tn7 and Tn3 transposons in Saccharomyces cerevisiae

Transposons are widely employed as tools for gene disruption. Ideally, they should display unbiased insertion behavior, and incorporate readily into any genomic DNA to which they are exposed. However, many transposons preferentially insert at specific nucleotide sequences. It is unclear to what extent such bias affects their usefulness as mutagenesis tools. Here, we examine...

Organelle DB: a cross-species database of protein localization and function

Nuwee Wiwatwattana 0 Anuj Kumar 0 0 Department of Molecular, Cellular, and Developmental Biology and Life Sciences Institute, University of Michigan , Ann Arbor, MI 48109-2216, USA To efficiently

A question of size: the eukaryotic proteome and the problems in defining it

We discuss the problems in defining the extent of the proteomes for completely sequenced eukaryotic organisms (i.e. the total number of protein-coding sequences), focusing on yeast, worm, fly and human. (i) Six years after completion of its genome sequence, the true size of the yeast proteome is still not defined. New small genes are still being discovered, and a large number of...

The TRIPLES database: a community resource for yeast molecular biology

Anuj Kumar Kei-Hoi Cheung Nick Tosches Peter Masiar Yang Liu Perry Miller Michael Snyder TRIPLES is a web-accessible database of TRansposonInsertion Phenotypes, Localization and Expression in

TRIPLES: a database of gene function in Saccharomyces cerevisiae

Using a novel multipurpose mini-transposon, we have generated a collection of defined mutant alleles for the analysis of disruption phenotypes, protein localization, and gene expression in Saccharomyces cerevisiae. To catalog this unique data set, we have developed TRIPLES, a Web-accessible database of TRansposon-Insertion Phenotypes, Localization and Expression in Saccharomyces...