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A Large-Scale Complex Haploinsufficiency-Based Genetic Interaction Screen in Candida albicans: Analysis of the RAM Network during Morphogenesis

The morphogenetic transition between yeast and filamentous forms of the human fungal pathogen Candida albicans is regulated by a variety of signaling pathways. How these pathways interact to orchestrate morphogenesis, however, has not been as well characterized. To address this question and to identify genes that interact with the Regulation of Ace2 and Morphogenesis (RAM...

A question of size: the eukaryotic proteome and the problems in defining it

We discuss the problems in defining the extent of the proteomes for completely sequenced eukaryotic organisms (i.e. the total number of protein-coding sequences), focusing on yeast, worm, fly and human. (i) Six years after completion of its genome sequence, the true size of the yeast proteome is still not defined. New small genes are still being discovered, and a large number of...

Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites

Prakash Chandra Mishra 0 Anuj Kumar 0 Amit Sharma 0 0 Address: Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology Aruna Asaf Ali Road , New

Characterization of W p -type of spaces involving fractional Fourier transform

The characterizations of W p -type of spaces and mapping relations between W- and W p -type of spaces are discussed by using the fractional Fourier transform. The uniqueness of the Cauchy problems is also investigated by using the same transform. MSC: 46F12, 46E15.

Complex dynamic of plankton–fish interaction with quadratic harvesting and time delay

The present paper deals with a food chain model consisting of three species phytoplankton, zooplankton and fish. We have divided the present paper into two parts. In the first part, we have assumed that the fish population is harvested using a non-linear harvesting function. Considering this rate of harvesting ‘E’ as a control parameter, we have estimated different ranges of...

Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli

; Revised 21 November 2015; Accepted 25 November 2015 Academic Editor: J. Justin Hsuan Copyright © 2015 Anuj Kumar Gupta et al. This is an open access article distributed under the Creative Commons

Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli

Aberrant glycosylation is one of the major hallmarks of cancer with altered gene expression signatures of sialyltransferases. ST3Gal-I, a sialyltransferase, is known to play a crucial role in sialylation of T antigen in bladder cancer and it has reported elevated expression in breast carcinogenesis with increased tumor progression stages. The aim of the current study is to...

Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains

Anuj Kumar Gupta,2 Madhvi Ahuja,1 Vinay Pathak,1 Utpal Sengupta,1 1Stanley Browne Laboratory, The Leprosy Mission Trust India, TLM Community Hospital Nand Nagari, 2Agilent Technologies India Pvt Ltd

Epigenetic Activation of Antibacterial Property of an Endophytic Streptomyces coelicolor Strain AZRA 37 and Identification of the Induced Protein Using MALDI TOF MS/MS

The endophytic Streptomyces coelicolor strain AZRA 37 was isolated from the surface sterilized root of Azadirachta indica A. Juss., commonly known as neem plant in India. Since only a few reports are available regarding epigenetic modulations of microbial entities, S. coelicolor was treated with different concentrations of 5-azacytidine for this purpose and evaluated for its...

Genome-scale identification, classification, and tissue specific expression analysis of late embryogenesis abundant (LEA) genes under abiotic stress conditions in Sorghum bicolor L.

. Manohar Rao, P. B. Kavi Kishor. Data curation: M. Nagaraju, Anuj Kumar. Formal analysis: M. Nagaraju, S. Anil Kumar, Palakolanu Sudhakar Reddy, Anuj Kumar, D. Manohar Rao, P. B. Kavi Kishor ... Sudhakar Reddy, Anuj Kumar. Supervision: D. Manohar Rao, P. B. Kavi Kishor. Visualization: M. Nagaraju, S. Anil Kumar, Palakolanu Sudhakar Reddy. Writing ? original draft: M. Nagaraju, Palakolanu Sudhakar

Genome-wide identification and characterization of gene family for RWP-RK transcription factors in wheat (Triticum aestivum L.)

Data curation: Anuj Kumar, Ritu Batra, Sandhya Tyagi. Formal analysis: Anuj Kumar, Ritu Batra, Vijay Gahlaut, Tinku Gautam, Sanjay Kumar, Mansi Sharma, Krishna Pal Singh. Methodology: Renu Pandey ... . Supervision: Harindra Singh Balyan, Renu Pandey, Pushpendra Kumar Gupta. Writing – original draft: Anuj Kumar, Ritu Batra. Writing – review & editing: Harindra Singh Balyan, Renu Pandey, Pushpendra Kumar

Genomic analysis of insertion behavior and target specificity of mini-Tn7 and Tn3 transposons in Saccharomyces cerevisiae

Transposons are widely employed as tools for gene disruption. Ideally, they should display unbiased insertion behavior, and incorporate readily into any genomic DNA to which they are exposed. However, many transposons preferentially insert at specific nucleotide sequences. It is unclear to what extent such bias affects their usefulness as mutagenesis tools. Here, we examine...

Hijacking microglial glutathione by inorganic arsenic impels bystander death of immature neurons through extracellular cystine/glutamate imbalance

, Lucknow-226001, Uttar Pradesh, IndiaVikas Singh, Ruchi Gera, Anuj Kumar Sharma & Debabrata GhoshAcademy of Scientific and Innovative Research (AcSIR), CSIR-IITR Campus, Lucknow-226001, Uttar Pradesh ... • PubMed • Google ScholarSearch for Ruchi Gera in:Nature Research journals • PubMed • Google ScholarSearch for Rajesh Kushwaha in:Nature Research journals • PubMed • Google ScholarSearch for Anuj Kumar

Industrial enzymes in bioindustrial sector development: An Indian perspective

, Canada, India and Malaysia 1 Anuj Kumar Chandel has an MSc and is currently pursuing a PhD in biotechnology at the Jawaharlal Nehru Technological University. He is also working with Celestial Labs Ltd

Influence of alumina/MWCNT hybrid nanoparticle additives on tribological properties of lubricants in turning operations

27.36%, respectively, as compared to alumina-based lubricants. hybrids; nanolubricants; MQL; MWCNT; tool wear; friction coefficient - Anuj Kumar SHARMA*, Jitendra Kumar KATIYAR, Shubrajit BHAUMIK ... , provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Anuj Kumar SHARMA. He received his PhD

Monoclonal Antibodies against Hepatitis C Genotype 3a Virus Like Particle Inhibit Virus Entry in Cell Culture System

Department of Biotechnology, Govt. of India. Dr. Soma Das was the recipient of S K Kothari postdoctoral Fellowship from UGC, Govt. of India. Anuj Kumar Dayal was a recipient of Junior Research Fellowship from

Organelle DB: a cross-species database of protein localization and function

Nuwee Wiwatwattana 0 Anuj Kumar 0 0 Department of Molecular, Cellular, and Developmental Biology and Life Sciences Institute, University of Michigan , Ann Arbor, MI 48109-2216, USA To efficiently

Organelle DB: an updated resource of eukaryotic protein localization and function

Organelle DB (http://organelledb.lsi.umich.edu) is a web-accessible relational database presenting a supplemented catalog of organelle-localized proteins and major protein complexes. Since its release in 2004, Organelle DB has grown by 20% to encompass over 30 000 proteins from 138 eukaryotic organisms. Each protein in Organelle DB is presented with its subcellular localization...

Phylogenetic and Preliminary Phenotypic Analysis of Yeast PAQR Receptors: Potential Antifungal Targets

Proteins belonging to the Progestin and AdipoQ Receptor (PAQR) superfamily of membrane bound receptors are ubiquitously found in fungi. Nearly, all fungi possess two evolutionarily distinct paralogs of PAQR protein, which we have called the PQRA and PQRB subtypes. In the model fungus Saccharomyces cerevisiae, these subtypes are represented by the Izh2p and Izh3p proteins...