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Search: authors:"Apostolos V. Tsolakis"

3 papers found.
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Synaptic Vesicle Protein 2 and Vesicular Monoamine Transporter 1 and 2 Are Expressed in Neuroblastoma

Neuroblastoma (NB), the most common extracranial cancer in childhood, exhibits neuroendocrine (NE) differentiation. Two well-established NE markers, chromogranin A (CgA) and synaptophysin (syn), are used in the histopathological diagnostics. Our aims were to explore if the NE markers synaptic vesicle protein 2 (SV2) and vesicular monoamine transporter 1 (VMAT1) and 2 (VMAT2) also...

Endocrine paraneoplastic syndromes in patients with neuroendocrine neoplasms

Abstract ObjectiveOur aim was to assess the prevalence of endocrine paraneoplastic syndromes (EPNS) in neuroendocrine neoplasms (NENs) and estimate its impact on patient outcomes.DesignThis is a retrospective analysis of 834 patients with NENs (611 gastrointestinal, 166 thoracic, 57 of unknown and various other primary origin). We included 719 consecutive NEN patients treated at...

Endogenous estrogen exposure in relation to distribution of histological type and estrogen receptors in gastric adenocarcinoma

BackgroundEstrogen might protect women against gastric adenocarcinoma of the intestinal histological type. We addressed this hypothesis and proposed that gastric estrogen receptors (ERs) are involved.MethodsA population-based cohort of patients with gastric adenocarcinoma diagnosed in 1958–2004 in the county of Stockholm was identified through the Swedish Cancer Register. The...