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Aberrant methylation-mediated downregulation of lncRNA SSTR5-AS1 promotes progression and metastasis of laryngeal squamous cell carcinoma

Basic Project Research Funded by Hebei Government (Hebei finance society (2017) No. 46). Authors’ contributions Baoshan Wang designed the study and wrote the manuscript. Lei Zhao detected the cells

Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma

Dysregulated long noncoding RNAs (lncRNAs) are involved in the development of tumor. Aberrant methylation is one of the most frequent epigenetic alterations that regulate the expression of genes. The aim of this study was to determine the expression and methylation status of ZNF667-AS1 and ZNF667, elucidate their biological function in the development of LSCC, and identify a cis...

Modelling and Analysis on Emergency Evacuation from Metro Stations

Efficient calculation on passenger evacuation performances under emergencies is crucial to the planning, design, and operation of metro systems as it is closely related to the safety of human lives. Four calculation methodologies including the China CDM, NFPA 130, control volume, and M/G/c/c models and a multiagent-based simulation approach are employed to calculate the...

Modelling and Analysis on Emergency Evacuation from Metro Stations

Efficient calculation on passenger evacuation performances under emergencies is crucial to the planning, design, and operation of metro systems as it is closely related to the safety of human lives. Four calculation methodologies including the China CDM, NFPA 130, control volume, and M/G/c/c models and a multiagent-based simulation approach are employed to calculate the...

Modelling and Analysis on Emergency Evacuation from Metro Stations

Efficient calculation on passenger evacuation performances under emergencies is crucial to the planning, design, and operation of metro systems as it is closely related to the safety of human lives. Four calculation methodologies including the China CDM, NFPA 130, control volume, and M/G/c/c models and a multiagent-based simulation approach are employed to calculate the...

Seismic detections of the 15 February 2013 Chelyabinsk meteor from the dense ChinArray

ChinArray is a dense portable broadband seismic network to cover the entire continental China, and the Phase I is deployed along the north-south seismic belt in southwest China. In this study, we analyze seismic data recorded on the ChinArray following the February 15, 2013 Chelyabinsk (Russia) meteor. This was the largest known object entering the Earth’s atmosphere since the...

Identification and transcriptomic profiling of genes involved in increasing sugar content during salt stress in sweet sorghum leaves

Wang 0 Equal contributors Key Laboratory of Plant Stress Research, College of life science, Shandong Normal University , Jinan, Shandong 250014 , PR China Background: Sweet sorghum is an annual C4 crop

Rational Formations of a Metro Train Improve Its Efficiencies of Both Traction Energy Utilization and Passenger Transport

Based on simulations of passenger transports of two representative types of metro trains in China, this study analyzes efficiencies of energy consumption and passenger transport of a metro train in the effect of its target speed, formation scale (FS) (i.e., length and mass of the formation), relative traction capacity (RTC) (i.e., ratio of the motoring cars to all its cars), and...

Influencing factors of seismic signals generated by un-tuned large volume airgun array in a land reservoir

Un-tuned large volume airgun array in a water reservoir is recently proposed as a new way to generate seismic waves on land. It can be used to explore the earth velocity structure and its temporal variations as well. However, the characteristics of seismic signals (especially far-field signals) from an airgun array in a reservoir and its affecting factors (firing pressure, airgun...

Composition of high frequency ambient noise from cross-correlation: A case study using a small aperture array

Long-time cross correlation of ambient noise has been proved as a powerful tool to extract Green’s function between two receivers. The study of composition of ambient noise is important for a better understanding of this method. Previous studies confirm that ambient noise in the long period (3 s and longer) mostly consists of surface wave, and 0.25–2.5 s noise consists more of...

Differential molecular information of maurotoxin peptide recognizing IKCa and Kv1.2 channels explored by computational simulation

Li 1 Baoshan Wang 0 0 College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072 , PR China 1 State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan

Effects of salt treatment and osmotic stress on V‐ATPase and V‐PPase in leaves of the halophyte Suaeda salsa

The Chenopodiaceae Suaeda salsa L. was grown under different salt concentrations and under osmotic stress. The fresh weight was markedly stimulated by 0.1 M NaCl, 0.4 M NaCl and 0.1 M KCl and reduced by osmotic stress (PEG iso‐osmotic to 0.1 M NaCl). Treatment with 0.4 M KCl severely damaged the plants. Membrane vesicle fractions containing tonoplast vesicles were isolated by...

Salinity treatment shows no effects on photosystem II photochemistry, but increases the resistance of photosystem II to heat stress in halophyte Suaeda salsa

Photosynthetic gas exchange, modulated chlorophyll fluorescence, rapid fluorescence induction kinetics, and the polyphasic fluorescence transients were used to evaluate PSII photochemsitry in the halophyte Suaeda salsa exposed to a combination of high salinity (100–400 mM NaCl) and heat stress (35–47.5 °C, air temperature). CO2 assimilation rate increased slightly with increasing...