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Search: authors:"Ben WJ Mol"

16 papers found.
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A clinically integrated curriculum in Evidence-based Medicine for just-in-time learning through on-the-job training: The EU-EBM project

Kaczor 8 Gianni Zanrei 2 Karin Pierer 10 Katarzyna Stawiarz 8 Regina Kunz 10 Ben WJ Mol 3 Khalid S Khan 5 7 0 CASPe (CASP Espana) , Joaquin Orozco 6, 1-F, 03006 Alicante , Spain 1 Academic Medical

A randomised clinical trial on cardiotocography plus fetal blood sampling versus cardiotocography plus ST-analysis of the fetal electrocardiogram (STAN®) for intrapartum monitoring

monitoring Westerhuis 3 Karel GM Moons 1 Erik van Beek 0 Saskia M Bijvoet 7 Addy P Drogtrop 6 Herman P van Geijn 7 Jan MM van Lith 5 Ben WJ Mol 4 9 Jan G Nijhuis 8 S Guid Oei 9 Martina M Porath 9

Disproportionate Intrauterine Growth Intervention Trial At Term: DIGITAT

Background Around 80% of intrauterine growth restricted (IUGR) infants are born at term. They have an increase in perinatal mortality and morbidity including behavioral problems, minor developmental delay and spastic cerebral palsy. Management is controversial, in particular the decision whether to induce labour or await spontaneous delivery with strict fetal and maternal...

Effectiveness of continuous glucose monitoring during diabetic pregnancy (GlucoMOMS trial); a randomised controlled trial

Background Hyperglycemia in pregnancy is associated with poor perinatal outcome. Even if pregnant women with diabetes are monitored according to current guidelines, they do much worse than their normoglycaemic counterparts, marked by increased risks of pre-eclampsia, macrosomia, and caesarean section amongst others. Continuous Glucose Monitoring (CGM) is a new method providing...

Harmonising Evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries

Background We developed and evaluated the outcomes of an e-learning course for evidence based medicine (EBM) training in postgraduate medical education in different languages and settings across five European countries. Methods We measured changes in knowledge and attitudes with well-developed assessment tools before and after administration of the course. The course consisted of...

How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review

Gemma Barnfield Susanne Weinbrenner Berit Meyerrose Theodoros N Arvanitis Andrea R Horvath Gianni Zanrei Regina Kunz Katja Suter Bernard Burnand Chantal Arditi Katrien Oude Rengerink Gee Harry Ben WJ Mol

Individual patient data meta-analysis of diagnostic and prognostic studies in obstetrics, gynaecology and reproductive medicine

Background In clinical practice a diagnosis is based on a combination of clinical history, physical examination and additional diagnostic tests. At present, studies on diagnostic research often report the accuracy of tests without taking into account the information already known from history and examination. Due to this lack of information, together with variations in design and...

Induction of labour versus expectant monitoring in women with pregnancy induced hypertension or mild preeclampsia at term: the HYPITAT trial

Background Hypertensive disorders, i.e. pregnancy induced hypertension and preeclampsia, complicate 10 to15% of all pregnancies at term and are a major cause of maternal and perinatal morbidity and mortality. The only causal treatment is delivery. In case of preterm pregnancies conservative management is advocated if the risks for mother and child remain acceptable. In contrast...

Obstetrical outcome valuations by patients, professionals, and laypersons: differences within and between groups using three valuation methods

Background Decision-making can be based on treatment preferences of the patient, the doctor, or by guidelines based on lay people's preferences. We compared valuations assigned by three groups: patients, obstetrical care professionals, and laypersons, for health states involving both mother and (unborn) child. Our aim was to compare the valuations of different groups using...

Prediction of pre-eclampsia: a protocol for systematic reviews of test accuracy

Background Pre-eclampsia, a syndrome of hypertension and proteinuria, is a major cause of maternal and perinatal morbidity and mortality. Accurate prediction of pre-eclampsia is important, since high risk women could benefit from intensive monitoring and preventive treatment. However, decision making is currently hampered due to lack of precise and up to date comprehensive...

Progesterone for the prevention of preterm birth in women with multiple pregnancies: the AMPHIA trial

Johannes J Duvekot 0 Jan Jaap HM Erwich 7 Tom HM Hasaart 6 Pieter Hummel 5 Ben WJ Mol 4 Jos PM Offermans 9 Charlotte M van Oirschot 8 Job G Santema 2 Hubertina CJ Scheepers 12 Willem A Schls

Teaching trainers to incorporate evidence-based medicine (EBM) teaching in clinical practice: the EU-EBM project

Background Evidence based medicine (EBM) is considered an integral part of medical training, but integration of teaching various EBM steps in everyday clinical practice is uncommon. Currently EBM is predominantly taught through theoretical courses, workshops and e-learning. However, clinical teachers lack confidence in teaching EBM in workplace and are often unsure of the...

The LIFESTYLE study: costs and effects of a structured lifestyle program in overweight and obese subfertile women to reduce the need for fertility treatment and improve reproductive outcome. A randomised controlled trial

Brinkhuis Carolien AM Koks Jan M Burggraaff Adrienne S Blankhart Denise AM Perquin Marie H Gerards Robert JAB Mulder Ed TCM Gondrie Ben WJ Mol Annemieke Hoek Background: In the Netherlands, 30% of subfertile

The effectiveness of a clinically integrated e-learning course in evidence-based medicine: A cluster randomised controlled trial

Background To evaluate the educational effects of a clinically integrated e-learning course for teaching basic evidence-based medicine (EBM) among postgraduates compared to a traditional lecture-based course of equivalent content. Methods We conducted a cluster randomised controlled trial in the Netherlands and the UK involving postgraduate trainees in six obstetrics and...

The inSIGHT study: costs and effects of routine hysteroscopy prior to a first IVF treatment cycle. A randomised controlled trial

BackgroundIn in vitro fertilization (IVF) and intracytoplasmatic sperm injection (ICSI) treatment a large drop is present between embryo transfer and occurrence of pregnancy. The implantation rate per embryo transferred is only 30%. Studies have shown that minor intrauterine abnormalities can be found in 11–45% of infertile women with a normal transvaginal sonography or...

When outcome is a balance: methods to measure combined utility for the choice between induction of labour and expectant management in mild risk pregnancy at term

Background When the primary and secondary outcomes of clinical studies yield ambiguous or conflicting recommendations, preference or valuation studies may help to overcome the decision problem. The present preference study is attached to two clinical studies (DIGTAT, ISRCT10363217; HYPITAT, ISRCT08132825) that evaluate induction of labour versus expectant management in term...