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Trends in multimorbidity and polypharmacy in the Flemish-Belgian population between 2000 and 2015

: Marjan van den Akker, Bert Vaes, Geert Goderis, Gijs Van Pottelbergh. Formal analysis: Se?verine Henrard. Investigation: Marjan van den Akker, Gijs Van Pottelbergh. Methodology: Marjan van den Akker ... , Bert Vaes, Se?verine Henrard. Project administration: Tine De Burghgraeve. Software: Se?verine Henrard. Supervision: Bert Vaes. Visualization: Tine De Burghgraeve, Se?verine Henrard. Writing

Treatment intentions of general practitioners regarding hypertension in the oldest old: a vignette study

Background The recent literature has shown that the risk of hypertension in the old strongly depends on their physical abilities. However, it is unknown whether general practitioners (GPs) adapt their treatment strategies to the patient’s independence. This study was conducted to investigate the treatment intentions of GPs for patients aged 80 and older with hypertension in...

Evaluating the scripts and thresholds of general practitioners for diagnosing heart failure in elderly people

Background Multiple diagnostic algorithms for heart failure exist. However, it is unclear whether these algorithms are incorporated in the ‘scripts’ clinicians use in every day practice. Scripts are networks of organised knowledge that are acquired and accumulated during clinical training and are refined with each clinical encounter. This study was conducted to evaluate the...

Association between atrial fibrillation, anticoagulation, risk of cerebrovascular events and multimorbidity in general practice: a registry-based study

Background To date, there has been no comprehensive study on the association between atrial fibrillation (AF) and multimorbidity. The present study investigated the epidemiology of AF and the association between multimorbidity and the onset of AF. In addition, the correlation between multimorbidity and the use of anticoagulants and the risk of cerebrovascular events considering...

The clinical impact of valvular heart disease in a population-based cohort of subjects aged 80 and older

Background In our ageing society, valvular heart diseases (VHD) have become an increasing public health problem. However, the lack of studies describing the impact of these diseases on the outcome of very old subjects makes it difficult to appreciate their real clinical burden. Methods Prospective, observational, population-based cohort study in Belgium. Five hundred fifty six...

Detection of potentially inappropriate prescribing in the very old: cross-sectional analysis of the data from the BELFRAIL observational cohort study

Background Little is known about the prevalence and clinical importance of potentially inappropriate prescribing instances (PIPs) in the very old (>80 years). The main objective was to describe the prevalence of PIPs according to START (Screening Tool to Alert doctors to Right Treatment; omissions) and,STOPP (Screening Tool of Older Person’s Prescriptions; over/misuse) and the...

Short-term prognostic value of forced expiratory volume in 1 second divided by height cubed in a prospective cohort of people 80 years and older

Ann Van Damme (Hoeilaart), Dr Sofie Dedeurwaerdere (Hoeilaart), Dr Bert Vaes (Hoeilaart), Dr Stein Bergiers (Hoeilaart), Dr Bernard Deman (Hoeilaart), Dr Edmond Charlier (Overijse), Dr Serge Tollet

The diagnostic accuracy of the MyDiagnostick to detect atrial fibrillation in primary care

Background Atrial fibrillation is very common in people aged 65 or older. This condition increases the risk of death, congestive heart failure and thromboembolic conditions. Many patients with atrial fibrillation are asymptomatic and a cerebrovascular accident (CVA) is often the first clinical presentation. Guidelines concerning the prevention of CVA recommend monitoring the...

The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients

Gillet (Mohiville), Dr Arlette Germay (Houyet), Dr Jan Craenen (Hoeilaart), Dr Luc Meeus (Hoeilaart), Dr Herman Docx (Hoeilaart), Dr Ann Van Damme (Hoeilaart), Dr Sofie Dedeurwaerdere (Hoeilaart), Dr Bert ... Vaes (Hoeilaart), Dr Stein Bergiers (Hoeilaart), Dr Bernard Deman (Hoeilaart), Dr Edmond Charlier (Overijse), Dr Serge Tollet (Overijse), Dr Eddy Van Keerberghen (Overijse), Dr Etienne Smets (Overijse

To screen or not to screen for peripheral arterial disease in subjects aged 80 and over in primary health care: a cross-sectional analysis from the BELFRAIL study

(Hoeilaart), Dr Sofie Dedeurwaerdere (Hoeilaart), Dr Bert Vaes (Hoeilaart), Dr Stein Bergiers (Hoeilaart), Dr Bernard Deman (Hoeilaart), Dr Edmond Charlier (Overijse), Dr Serge Tollet (Overijse), Dr Eddy Van

Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis

Background The Short Physical Performance Battery (SPPB) is a well-established tool to assess lower extremity physical performance status. Its predictive ability for all-cause mortality has been sparsely reported, but with conflicting results in different subsets of participants. The aim of this study was to perform a meta-analysis investigating the relationship between SPPB...

Diagnostic accuracy of plasma NT-proBNP levels for excluding cardiac abnormalities in the very elderly

Background In the elderly the diagnosis of chronic heart failure is often challenging and the availability of echocardiography can be limited. Plasma levels of NT-proBNP are valuable tools to diagnose patients with heart failure. However, the performance of this biomarker to detect cardiac abnormalities in the very elderly remains unclear. The aims of this study were to...

The BELFRAIL (BFC80+) study: a population-based prospective cohort study of the very elderly in Belgium

(Hoeilaart), Dr Bert Vaes (Hoeilaart), Dr Stein Bergiers (Hoeilaart), Dr Bernard Deman (Hoeilaart), Dr Edmond Charlier (Overijse), Dr Serge Tollet (Overijse), Dr Eddy Van Keerberghen (Overijse), Dr Etienne