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Attribution of the Last Glacial Maximum climate formation

To better understand what determines the Last Glacial Maximum (LGM) cold and dry climate, a suite of numerical experiments with the Nanjing University of Information Science and Technology Earth System Model version 1 are conducted to assess the relative contributions of individual external forcings, including greenhouse gases (GHGs), ice sheets (IS), land-sea configuration (LSC...

Subxiphoid vs transthoracic approach thoracoscopic surgery for spontaneous pneumothorax: a propensity score-matched analysis

The transthoracic thoracoscopic surgery is currently accepted as a favorable technique for bullectomy for primary spontaneous pneumothorax. Recently, uniportal subxiphoid thoracoscopic surgery has been proposed as an alternative to conventional transthoracic thoracoscopic surgery. From November 2014 and January 2016, 127 consecutive patients who met the inclusion criteria were...

Strong Cosmic Censorship in higher-dimensional Reissner-Nordström-de Sitter spacetime

Abstract : It was recently shown that Strong Cosmic Censorship might be violated for near-extremally-charged black holes in 4-dimensional de Sitter space under scalar perturbations. Here, we extend the study of neutral massless scalar perturbations in higher dimensions and discuss the dimensional influence on the validity of Strong Cosmic Censorship hypothesis. By giving an...

Strong cosmic censorship for the massless Dirac field in the Reissner-Nordstrom-de Sitter spacetime

Abstract We present the Fermi story of strong cosmic censorship in the near-extremal Reissner-Nordstrom-de Sitter black hole. To this end, we first derive from scratch the criterion for the quasi-normal modes of Dirac field to violate strong cosmic censorship in such a background, which turns out to be exactly the same as those for Bose fields, although the involved energy...

Single and double aging treatments on Mg97Zn1Y2 alloy

The development of magnesium alloys was limited due to the low absolute strength and poor corrosion resistance. It was found that the optimal performance could not be achieved in some alloys by a single quenching and aging treatment, but could be achieved after a graded aging or multiple-stage aging heat treatment. The Mg97Zn1Y2 alloy was prepared and subjected to single and...

Dynamic moisture mode versus moisture mode in MJO dynamics: importance of the wave feedback and boundary layer convergence feedback

The Madden–Julian oscillation (MJO) is an equatorial eastward moving system with a planetary-scale coupled Kelvin–Rossby wave structure. The equatorial waves and their interaction with convection are expected to play an important role in MJO dynamics. Using the trio-interaction model for essential MJO dynamics, this study investigates the importance of dynamic feedback that...

How does the Asian summer precipitation-ENSO relationship change over the past 544 years?

The secular change of the Asian monsoon (AM)-El Niño–Southern Oscillation (ENSO) relationship has been recognized as a specter for seasonal forecast. The causes of such changes have not been well understood. How the monsoon-ENSO relationship underwent secular changes beyond instrumental period has rarely been discussed. Here we explore the multidecadal to centennial changes of...

Study on the Pressure Characteristics of Shock Wave Propagating across Multilayer Structures during Underwater Explosion

The propagation of the shock wave across multilayer structures during underwater explosion is a very complex physical phenomenon, involving violent fluid-structure interaction (FSI) problems. In this paper, the coupled Eulerian–Lagrangian (CEL) method in AUTODYN is used to simulate the process of shock wave propagation and solve FSI problems. Firstly, the governing equation and...

Efficient production of extracellular pullulanase in Bacillus subtilis ATCC6051 using the host strain construction and promoter optimization expression system

Bacillus subtilis has been widely used as a host for heterologous protein expression in food industry. B. subtilis ATCC6051 is an alternative expression host for the production of industrial enzymes, and exhibits favorable growth properties compared to B. subtilis 168. Extracellular expression of pullulanase from recombinant B. subtilis is still limited due to the issues on...

Proteomic profiling of liver from Elaphe taeniura, a common snake in eastern and southeastern Asia

Snake liver has been implicated in the adaptation of snakes to a variety of habitats. However, to date, there has been no systematic analysis of snake liver proteins. In this study, we undertook a proteomic analysis of liver from the colubrid snake Elaphe taeniura using a combination of two-dimensional electrophoresis (2-DE) and matrix-assisted laser desorption/ionization time of...

PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases

College, Thomas Jefferson University, Philadelphia, PA 19107, USA Correspondence should be addressed to Bin Wang; Received 7 May 2018; Accepted 14 July 2018; Published 29 July 2018 Academic Editor ... : Kazuhiro Shiizaki Copyright © 2018 Yanmei Yang and Bin Wang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases

College, Thomas Jefferson University, Philadelphia, PA 19107, USA Correspondence should be addressed to Bin Wang; Received 7 May 2018; Accepted 14 July 2018; Published 29 July 2018 Academic Editor ... : Kazuhiro Shiizaki Copyright © 2018 Yanmei Yang and Bin Wang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

Improving MJO simulation by enhancing the interaction between boundary layer convergence and lower tropospheric heating

It has been a great challenge for global weather and climate models to simulate realistic Madden–Julian Oscillation (MJO) while keeping global energy and water balance unaffected. This work demonstrates that, in the Nanjing University of Information Science and Technology Earth System Model, enhanced boundary layer (BL) convergence feedback to the lower tropospheric heating in...

Synthesis of Sea Urchin-Like NiCo2O4 via Charge-Driven Self-Assembly Strategy for High-Performance Lithium-Ion Batteries

In this study, hydrothermal synthesis of sea urchin-like NiCo2O4 was successfully demonstrated by a versatile charge-driven self-assembly strategy using positively charged poly(diallydimethylammonium chloride) (PDDA) molecules. Physical characterizations implied that sea urchin-like microspheres of ~ 2.5 μm in size were formed by self-assembly of numerous nanoneedles with a...

The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells

Conceptualization: Xu Chao, Jieqiong Wu. Data curation: Guoquan Wang, Yuping Tang. Methodology: Changhu Dong, Hong Li, Bin Wang, Jieqiong Wu. Writing ? original draft: Jiarong Zhao. Writing ? review & editing: Xu

Scalar field condensation behaviors around reflecting shells in Anti-de Sitter spacetimes

the anonymous referee for the constructive suggestions to improve the manuscript. Yan Peng was supported by the Shandong Provincial Natural Science Foundation of China under Grant no. ZR2018QA008. Bin ... Wang would like to acknowledge the support by National Basic Research Program of China (973 Program 2013CB834900) and National Natural Science Foundation of China. And Yunqi Liu acknowledge the support

Suppressing microRNA-29c promotes biliary atresia-related fibrosis by targeting DNMT3A and DNMT3B

This study was designed to investigate the potential role of microRNA-29c (miR-29c) in biliary atresia-related fibrosis. The expression of miR-29c was determined in 15 pairs of peripheral blood samples from infants with biliary atresia (BA) and infants with non-BA neonatal cholestasis using quantitative real-time PCR. EMT was established by induction with TGF-β1 in HIBEpiC cells...

A quantitative analysis of global environmental protection values based on the world values survey data from 1994 to 2014

The four most recent sub-datasets of the World Value Survey (WVS) database (i.e., WVS3, WVS4, WVS5, and WVS6) contain a total of 25 non-numerical variables of environmental protection values and cover the period from 1994 to 2014. This study utilized these datasets to obtain the spatiotemporal distributions of the values and provided a preliminary analysis of the environmental...

Identification and expression analysis of genes with pathogen-inducible cis-regulatory elements in the promoter regions in Oryza sativa

BackgroundComplex co-regulatory networks in plants may elicit responses during pathogen infections. A number of genes are activated when these responses take place. Identification of these genes would shed new light on understanding the mechanisms of rice response to pathogen infections and the elucidation of crosstalk among diverse signaling networks in rice disease resistance...