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Decontamination and optimization study of hexavalent chromium on modified chicken feather using response surface methodology

Present research highlighted the efficacy of alkali-treated (1% NaOH) chicken feather toward removal of Cr(VI) from aqueous solution through batch study. Box–Behnken design (BBD) by response surface methodology was used to optimize the adsorption process. Kinetics and sorption isotherms have been determined considering the effect of initial metal concentration, adsorbent dose...

Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA

AdhyaUniversity of Nebraska Medical Center, Nebraska, NE, USASanjib Chaudhary AuthorsSearch for Kanchan Kumari in:Nature Research journals • PubMed • Google Scholar Search for Biswajit Das in:Nature Research

Analysis of precipitation for the past 20th century and its multi-decadal oscillation: a case study of Bankura Town, Bankura, West Bengal

Biswajit Das 0 Subodh Chandra Pal 0 0 Department of Geography, The University of Burdwan , Burdwan 713104, West Bengal , India The present investigation is based  on maximum monthly precipitation for the

Numerical Solution of First-Order Linear Differential Equations in Fuzzy Environment by Runge-Kutta-Fehlberg Method and Its Application

The numerical algorithm for solving “first-order linear differential equation in fuzzy environment” is discussed. A scheme, namely, “Runge-Kutta-Fehlberg method,” is described in detail for solving the said differential equation. The numerical solutions are compared with (i)-gH and (ii)-gH differential (exact solutions concepts) system. The method is also followed by complete...

Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis

Chemical regulation of macrophage function is one key strategy for developing host-directed adjuvant therapies for tuberculosis (TB). A critical step to develop these therapies is the identification and characterization of specific macrophage molecules and pathways with a high potential to serve as drug targets. Using a barcoded lentivirus-based pooled short-hairpin RNA (shRNA...

Biosorption of carbaryl from aqueous solution onto Pistia stratiotes biomass

In this work, adsorption of carbaryl from aqueous solution on Pistia stratiotes biomass was investigated. The effects of operating parameters such as initial concentration, pH, adsorbent dose and contact time on the adsorption of carbaryl were analyzed using response surface methodology. The proposed quadratic model for central composite design fitted very well to the...

Neural network model and isotherm study for removal of phenol from aqueous solution by orange peel ash

Artificial Neural Network model and isotherm study were done to predict the removal efficiency of phenol. An inexpensive adsorbent was developed from orange peel ash (OPA) for effective uptake of phenol from aqueous solution. The influence of different experimental parameters (initial concentration, pH, adsorbents dose, contact time, stirring rate and temperature) on phenol...

Removal of arsenic(III) and arsenic(V) on chemically modified low-cost adsorbent: batch and column operations

Batch and column operations were performed utilizing thioglycolated sugarcane carbon (TSCC), a low-cost adsorbent, to remove As(III) and As(V) from aqueous systems. Under optimized batch conditions, the TSCC could remove up to 92.7 and 91.4 % for As(III) and As(V), respectively. An artificial neural network model showed the validity of TSCC as a preferable adsorbent for arsenic...

Tissue-Specific Upregulation of MDS/EVI Gene Transcripts in the Intestine by Thyroid Hormone during Xenopus Metamorphosis

Background Intestinal remodeling during amphibian metamorphosis resembles the maturation of the adult intestine during mammalian postembryonic development when the adult epithelial self-renewing system is established under the influence of high concentrations of plasma thyroid hormone (T3). This process involves de novo formation and subsequent proliferation and differentiation...

Genome-wide identification of Xenopus matrix metalloproteinases: conservation and unique duplications in amphibians

Background Matrix metalloproteinases (MMPs) are members of the superfamily of Zn2+ dependent extracellular or membrane-bound endopeptidases which have been implicated to play critical roles in vertebrate development and human pathogenesis. A number of MMP genes have been found to be upregulated in some or all organs during frog metamorphosis, suggesting that different MMPs may...

Impairment of ultrastructure and cytoskeleton during progression of cardiac hypertrophy to heart failure

, Biswajit Das & Subha SenDepartment of Anatomic Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USAJames McMahon AuthorsSearch for Anasuya Gupta in:Nature Research ... Biswajit Das in:Nature Research journals • PubMed • Google ScholarSearch for James McMahon in:Nature Research journals • PubMed • Google ScholarSearch for Subha Sen in:Nature Research journals • PubMed

Studies on Xenopus laevis intestine reveal biological pathways underlying vertebrate gut adaptation from embryo to adult

Background To adapt to its changing dietary environment, the digestive tract is extensively remodeled from the embryo to the adult during vertebrate development. Xenopus laevis metamorphosis is an excellent model system for studying mammalian gastrointestinal development and is used to determine the genes and signaling programs essential for intestinal development and maturation...

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

Next Generation Sequencing (NGS) technologies are used to detect somatic mutations in tumors and study germ line variation. Most NGS studies use DNA isolated from whole blood or fresh frozen tissue. However, formalin-fixed paraffin-embedded (FFPE) tissues are one of the most widely available clinical specimens. Their potential utility as a source of DNA for NGS would greatly...