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TaWRKY68 responses to biotic stresses are revealed by the orthologous genes from major cereals

WRKY transcription factors have been extensively characterized in the past 20 years, but in wheat, studies onWRKY genes and their function are lagging behind many other species. To explore the function of wheat WRKY genes, we identified a TaWRKY68 gene from a common wheat cultivar. It encodes a protein comprising 313 amino acids which harbors 19 conserved motifs or active sites...

Efficacy Comparison of Preprandial and Postprandial Prandilin 25 Administration in Patients with Newly Diagnosed Type 2 Diabetes Using a Continuous Glucose Monitoring System

design of the study. Yong Luo, Wen-ji Ni, BO Ding, Xiang-hong Xu conducted the study and collected data. Yong Luo, Wen-ji Ni, and Jian Zhu contributed to data analysis. Jian Zhu contributed to manuscript ... writing. Jian Zhu and Jian-hua Ma provided final approval of the manuscript. Disclosures The authors (Yong Luo, Wen-ji Ni, BO Ding, Xiang-hong Xu, Lei Ye, Jian-hua Ma, Jian Zhu) have no conflict of

Insulin Injection Technique is Associated with Glycemic Variability in Patients with Type 2 Diabetes

, and XFS conducted the study and collected data. LY contributed to the data analysis. LY, and FFL wrote and gave final approval to the manuscript. Disclosures Lu Yuan, Fengfei Li, Ting Jing, Bo Ding

Comparison of Efficacy and Economic Value of Prandilin 25 and Humalog Mix 25 in Patients with Newly Diagnosed Type 2 Diabetes by a Continuous Glucose Monitoring System

, Wen-ji Ni, Bo Ding, and Xiang-hong Xu contributed to the conduct/data collection. Yong Luo, Xue-qin Wang, and Jian Zhu contributed to data analysis. Jian Zhu and Yong Luo contributed to manuscript ... writing. Jian-hua Ma and Jian Zhu provided final approval of the manuscript. Disclosures Yong Luo, Xue-qin Wang, Wen-ji Ni, BO Ding, Xiang-hong Xu, Lei Ye, Jian-hua Ma, and Jian Zhu have nothing to

Orbital sparganosis in an 8-year boy: a case report

Sparganosis is one of the neglected but important food-borne parasitic zoonoses, with higher prevalence in Asian countries. The infection is commonly located in the subcutaneous tissue, brain, breast, and lung, but fewer reported infections involve the eye. Because the majority of patients with sparganosis are adults, it is likely to be missed in children. An 8-year-old boy...

Treatment trends in patients with asthma–COPD overlap syndrome in a COPD cohort: findings from a real-world survey

Treatment trends in patients with asthma-COPD overlap syndrome in a COPD cohort: findings from a real-world survey Bo Ding,1 Mark Small2 1AstraZeneca Gothenburg, Mölndal, Sweden; 2Adelphi Real World

Disease Burden of Mild Asthma: Findings from a Cross-Sectional Real-World Survey

accordance with the rules of the US Health Insurance Portability and Accountability Act 1996. IRB approval was not necessary or sought.?? Disclosures. Bo Ding is an employee of AstraZeneca. Mark Small is an

COPD symptom burden: impact on health care resource utilization, and work and activity impairment

COPD symptom burden: impact on health care resource utilization, and work and activity impairment Bo Ding,1 Mark Small,2 Gina Bergström,3 Ulf Holmgren3 1Medical Evidence and Observational Research

A cross-sectional assessment of the burden of COPD symptoms in the US and Europe using the National Health and Wellness Survey

A cross-sectional assessment of the burden of COPD symptoms in the US and Europe using the National Health and Wellness Survey Bo Ding,1 Marco DiBonaventura,2 Niklas Karlsson,1 Gina Bergström,1 Ulf ... International Journal of COPD a cross-sectional assessment of the burden of COPD symptoms in the Us and europe using the national health and Wellness survey Bo Ding Marco DiBonaventura n iklas

MicROS-drt: supporting real-time and scalable data distribution in distributed robotic systems

A primary requirement in distributed robotic software systems is the dissemination of data to all interested collaborative entities in a timely and scalable manner. However, providing such a service in a highly dynamic and resource-limited robotic environment is a challenging task, and existing robot software infrastructure has limitations in this aspect. This paper presents a...

Electroconvulsive therapy-induced brain functional connectivity predicts therapeutic efficacy in patients with schizophrenia: a multivariate pattern recognition study

Previous studies suggested that electroconvulsive therapy can influence regional metabolism and dopamine signaling, thereby alleviating symptoms of schizophrenia. It remains unclear what patients may benefit more from the treatment. The present study sought to identify biomarkers that predict the electroconvulsive therapy response in individual patients. Thirty-four schizophrenia...

HOTAIR rs7958904 polymorphism is associated with increased cervical cancer risk in a Chinese population

Previously, we have identified single nucleotide polymorphisms (SNPs) rs7958904 and rs4759314 in long non-coding RNA HOX transcript antisense RNA (HOTAIR) were significantly associated with risk of colorectal and gastric cancer, respectively. Here, we aimed to investigate the association between HOTAIR SNPs and cervical cancer (CC) susceptibility. A total of 1209 cases and 1348...

Lethality of PAK3 and SGK2 shRNAs to Human Papillomavirus Positive Cervical Cancer Cells Is Independent of PAK3 and SGK2 Knockdown

The p21-activated kinase 3 (PAK3) and the serum and glucocorticoid-induced kinase 2 (SGK2) have been previously proposed as essential kinases for human papillomavirus positive (HPV+) cervical cancer cell survival. This was established using a shRNA knockdown approach. To validate PAK3 and SGK2 as potential targets for HPV+ cervical cancer therapy, the relationship between shRNA...

The flavonoid TL-2-8 induces cell death and immature mitophagy in breast cancer cells via abrogating the function of the AHA1/Hsp90 complex

contribution Hui-juan LIU, Xiao-xiao JIANG, Yi-zhen GUO, Fang-hui SUN, Xin-hui KOU, Yong BAO, Zhu-qing ZHANG, Zhao-hu LIN, and Ting-bo DING performed the experiments; Hui-juan LIU, Lan JIANG and Yong-hua YANG

Normalization and noise reduction for single cell RNA-seq experiments

A major roadblock towards accurate interpretation of single cell RNA-seq data is large technical noise resulted from small amount of input materials. The existing methods mainly aim to find differentially expressed genes rather than directly de-noise the single cell data. We present here a powerful but simple method to remove technical noise and explicitly compute the true gene...

Begonia jinyunensis (Begoniaceae, section Platycentrum), a new palmately compound leaved species from Chongqing, China

) . In a botanical survey of the nature reserve in July 2013, Bo Ding, Qian Wang, and Hai-Jun Wen collected an unknown Begonia of sect. Platycentrum with palmately compound leaves and sent it to Ching-I ... study Living collections of Begonia jinyunensis (Bo Ding 20130701, Ching-I Peng 24108, 24109, 24110) were used for morphological observations. In addition, herbarium specimens representative of B

Mining Genes Involved in Insecticide Resistance of Liposcelis bostrychophila Badonnel by Transcriptome and Expression Profile Analysis

Background Recent studies indicate that infestations of psocids pose a new risk for global food security. Among the psocids species, Liposcelis bostrychophila Badonnel has gained recognition in importance because of its parthenogenic reproduction, rapid adaptation, and increased worldwide distribution. To date, the molecular data available for L. bostrychophila is largely limited...

De Novo Assembly, Gene Annotation, and Marker Discovery in Stored-Product Pest Liposcelis entomophila (Enderlein) Using Transcriptome Sequences

Background As a major stored-product pest insect, Liposcelis entomophila has developed high levels of resistance to various insecticides in grain storage systems. However, the molecular mechanisms underlying resistance and environmental stress have not been characterized. To date, there is a lack of genomic information for this species. Therefore, studies aimed at profiling the L...