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Multivariate analysis of genomic variables, effective population size, and mutation rate

ObjectiveThe relationship between genomic variables (genome size, gene number, intron size, and intron number) and evolutionary forces has two implications. First, they help to unravel the mechanism underlying genome evolution. Second, they provide a solution to the debate over discrepancy between genome size variation and organismal complexity. Previously, a clear correlation...

Multivariate analysis of genomic variables, effective population size, and mutation rate

The relationship between genomic variables (genome size, gene number, intron size, and intron number) and evolutionary forces has two implications. First, they help to unravel the mechanism underlying genome evolution. Second, they provide a solution to the debate over discrepancy between genome size variation and organismal complexity. Previously, a clear correlation between...

In vitro/vivo drug release and anti-diabetic cardiomyopathy properties of curcumin/PBLG-PEG-PBLG nanoparticles

In vitro/vivo drug release and anti-diabetic cardiomyopathy properties of curcumin/PBLG-PEG-PBLG nanoparticles Fei Tong, Rongkui Chai, Haiying Jiang, Bo DongDepartment of Pathology and Pathophysiology, Provincial Key Discipline of Pharmacology, Jiaxing University Medical College, Jiaxing, Zhejiang, People’s Republic of China Background: The objective of this study was to survey...

Identification and characterization of microRNAs involved in ascidian larval metamorphosis

Metamorphosis takes place within the life cycle of most marine invertebrates. The marine ascidian is a classical model to study complex cellular processes and underlying molecular mechanisms involved in its larval metamorphosis. The detailed molecular signaling pathways remain elusive, though extracellular signal-regulated kinases (ERKs) and c-Jun N-terminal kinase (JNK) have...

Analyzing Breathing Signals and Swallow Sequence Locality for Solid Food Intake Monitoring

Self-reported questionnaires are widely used by researchers for analyzing the dietary behavior of overweight and obese individuals. It has been established that questionnaire-based data collection often suffers from high errors due to its reporting subjectivity. Automatic swallow detection, as an alternative to questionnaires, is proposed in this paper to avoid such subjectivity...

Management of screwdriver-induced penetrating brain injury: a case report

Background Penetrating brain injury (PBI) can be caused by several objects ranging from knives to chopsticks. However, an assault with long and electric screwdriver is a peculiar accident and is relatively rare. Because of its rarity, the treatments of such injury are complex and nonstandardized. Case presentation We presented a case of a 54-year-old female who was stabbed with a...

Numerical simulation study on monoblock casting process of ultra-slender structural components and experimental validation

-dong Zeng, Hao Sun, Jia-yun Chen , and Xian-fei Wang Shanghai Spaceflight Precision Machinery Institute , Shanghai 201600 , China Substrate, a typical ultra-slender aluminum alloy structural components

Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats

Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats Fei Tong,1 Bo Dong,1 Rongkui Chai,1 Ke Tong,2,3 Yini Wang,4 Shipiao Chen,1

The Protective Effect of Salidroside on Hypoxia-Induced Corpus Cavernosum Smooth Muscle Cell Phenotypic Transformation

Huang,2 Gang Chen,2 Hui-ying Fu,1,4 and Bo-dong Lv2,4 1The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China 2Department of Urology, The Second Affiliated Hospital of ... and Western Medicine, Zhejiang Provincial Key Laboratory of Traditional Chinese Medicine, Hangzhou, China Correspondence should be addressed to Hui-ying Fu; moc.621@131yhf and Bo-dong Lv; moc.621

The Protective Effect of Salidroside on Hypoxia-Induced Corpus Cavernosum Smooth Muscle Cell Phenotypic Transformation

Huang,2 Gang Chen,2 Hui-ying Fu,1,4 and Bo-dong Lv2,4 1The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China 2Department of Urology, The Second Affiliated Hospital of ... and Western Medicine, Zhejiang Provincial Key Laboratory of Traditional Chinese Medicine, Hangzhou, China Correspondence should be addressed to Hui-ying Fu; moc.621@131yhf and Bo-dong Lv; moc.621

The Nup98 Homolog APIP12 Targeted by the Effector AvrPiz-t is Involved in Rice Basal Resistance Against Magnaporthe oryzae

BackgroundThe effector AvrPiz-t of Magnaporthe oryzae has virulence function in rice. However, the mechanism underlying its virulence in host is not fully understood.ResultsIn this study, we analyzed the function of AvrPiz-t interacting protein 12 (APIP12) in rice immunity. APIP12 significantly bound to AvrPiz-t and APIP6 in its middle portion and N-terminus, respectively, in...

The platelet-derived growth factor receptor/STAT3 signaling pathway regulates the phenotypic transition of corpus cavernosum smooth muscle in rats

Erectile dysfunction (ED) is a common clinical disease that is difficult to treat. We previously found that hypoxia modulates the phenotype of primary corpus cavernosum smooth muscle cells (CCSMCs) in rats, but the underlying molecular mechanism is still unknown. Platelet-derived growth factor receptor (PDGFR)-related signaling pathways are correlated with cell phenotypic...

Microtubule-dependent balanced cell contraction and luminal-matrix modification accelerate epithelial tube fusion

Present address: Department of Imaging Science, Center for Novel Science Initiatives, National Institutes of Natural Sciences, Myodaiji-Cho, Okazaki, Aichi 444-8787, Japan Bo Dong Present address: College ... -minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, JapanKagayaki Kato, Bo Dong, Housei Wada & Shigeo HayashiFeinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, Illinois 60611

Robust Linear Quadratic Regulator via Sliding Mode Guidance for Spacecraft Orbiting a Tumbling Asteroid

Aiming to ensure the stability of the spacecraft with multiuncertainties and mitigate the threat of the initial actuator saturation, a Robust Linear Quadratic Regulator (RLQR) via sliding mode guidance (SMG) for orbiting a tumbling asteroid is proposed in this paper. The orbital motion of the spacecraft near a tumbling asteroid is modelled in the body-fixed frame considering the...

A fat body-derived apical extracellular matrix enzyme is transported to the tracheal lumen and is required for tube morphogenesis in Drosophila

Bo Dong Guangxia Miao Shigeo Hayashi () The apical extracellular matrix plays a central role in epithelial tube morphogenesis. In the Drosophila tracheal system, Serpentine (Serp), a secreted chitin

Decentralized Reinforcement Learning Robust Optimal Tracking Control for Time Varying Constrained Reconfigurable Modular Robot Based on ACI and -Function

2013; Accepted 13 November 2013 Academic Editor: M. Onder Efe Copyright © 2013 Bo Dong and Yuanchun Li. This is an open access article distributed under the Creative Commons Attribution License

Decentralized Reinforcement Learning Robust Optimal Tracking Control for Time Varying Constrained Reconfigurable Modular Robot Based on ACI and -Function

2013; Accepted 13 November 2013 Academic Editor: M. Onder Efe Copyright © 2013 Bo Dong and Yuanchun Li. This is an open access article distributed under the Creative Commons Attribution License