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Search: authors:"Brechje de Gier"

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Disease burden of neonatal invasive Group B Streptococcus infection in the Netherlands

BCoDE toolkit version 1.4. (XLS) S3 File. Neonatal GBS meningitis model import file for BCoDE toolkit version 1.4. (XLS) Author Contributions Conceptualization: Brechje de Gier, Elisabeth A. M. Sanders ... , Merijn W. Bijlsma. Data curation: Merel N. van Kassel, Merijn W. Bijlsma. Formal analysis: Brechje de Gier, Merel N. van Kassel. 9 / 12 Methodology: Brechje de Gier. Project administration: Diederik van

CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel

Background Chronic schistosomiasis is associated with T cell hypo-responsiveness and immunoregulatory mechanisms, including induction of regulatory T cells (Tregs). However, little is known about Treg functional capacity during human Schistosoma haematobium infection. Methodology CD4+CD25hiFOXP3+ cells were characterized by flow cytometry and their function assessed by analysing...

Micronutrient-Fortified Rice Can Increase Hookworm Infection Risk: A Cluster Randomized Trial

Background Fortification of staple foods is considered an effective and safe strategy to combat micronutrient deficiencies, thereby improving health. While improving micronutrient status might be expected to have positive effects on immunity, some studies have reported increases in infections or inflammation after iron supplementation. Objective To study effects of micronutrient...