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Search: authors:"Bruno Müller-Oerlinghausen"

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Lithium in the episode and suicide prophylaxis and in augmenting strategies in patients with unipolar depression

Background Depressive disorders are a leading cause of the global burden of disease and are associated with high recurrent often continuing morbidity and high excess mortality by suicide and cardiovascular disease. Whilst there are established, effective and cost-effective treatments for depression, their long-term management is often neglected: there is continuing controversy...

Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters

Michael Bauer Alberto Bocchetta Lorenza Bolzani Cynthia V. Calkin Caterina Chillotti Diego Hidalgo‑Mazzei Mirko Manchia Bruno MüllerOerlinghausen Andrea Murru Giulio Perugi Marco Pinna Giuseppe Quaranta

Commentary on a recent review of lithium toxicity: what are its implications for clinical practice?

A recent paper by McKnight et al. in The Lancet has provided the first formal meta-analysis of the more common adverse reactions to lithium. The authors analyzed 385 studies and focused mainly on the harmful effects of lithium on the kidney, the thyroid and parathyroid glands, body weight, skin and congenital malformations. Their contribution is important and welcome, but as a...

Stability of lithium treatment in bipolar disorder - long-term follow-up of 346 patients

Background The purpose of this study was to investigate the effectiveness and stability of long-term lithium treatment in a prospective, international, multicenter cohort of bipolar patients in a naturalistic setting. Methods Patients were selected according to DSM IV criteria for bipolar disorder and required long-term treatment. They were prospectively followed and documented...