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Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Mediterranean region based on mitochondrial sequences

Nova de Lisboa) and Mariana Sousa for their support in imaging and design. Author Contributions Conceptualization: Carolina Bruno de Sousa, Jo?o Varela. Data curation: Carolina Bruno de Sousa, Cymon J ... . Cox, Lu??s Brito, Maria Madalena Pav?o, Ricardo Bermejo, Manuela Parente, Jo?o Varela. 18 / 23 Formal analysis: Carolina Bruno de Sousa, Lu??s Brito, Maria Madalena Pav?o, Ana Ferreira. Funding

Therapeutic Potential of Caspofungin Combined with Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia: A Pilot Study in Mice

Pneumocystis pneumonia (PcP) is a major cause of mortality and morbidity in immunocompromised patients. There are limited alternative therapeutic choices to trimethoprim-sulfamethoxazole (TMP-SMX) which is the standard first line therapy/prophylaxis for PcP. The efficacy of low doses of caspofungin and caspofungin in association with TMP-SMX standard-prophylactic dose was...

Duffy Negative Antigen Is No Longer a Barrier to Plasmodium vivax – Molecular Evidences from the African West Coast (Angola and Equatorial Guinea)

Background Plasmodium vivax shows a small prevalence in West and Central Africa due to the high prevalence of Duffy negative people. However, Duffy negative individuals infected with P. vivax have been reported in areas of high prevalence of Duffy positive people who may serve as supply of P. vivax strains able to invade Duffy negative erythrocytes. We investigated the presence...