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15 papers found.
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Community health workers: to train or to restrain? A longitudinal survey to assess the impact of training community health workers in the Bolama Region, Guinea-Bissau

Background The shortage in human resources for health affects most dramatically developing countries which frequently use community health workers (CHW) as the basis for health programmes and services. The traditional definition refers CHWs as members of the community who are recruited and trained in health prevention and promotion to provide services within their community. In...

Community health workers: to train or to restrain? A longitudinal survey to assess the impact of training community health workers in the Bolama Region, Guinea-Bissau

The shortage in human resources for health affects most dramatically developing countries which frequently use community health workers (CHW) as the basis for health programmes and services. The traditional definition refers CHWs as members of the community who are recruited and trained in health prevention and promotion to provide services within their community. In Guinea...

Duffy Negative Antigen Is No Longer a Barrier to Plasmodium vivax – Molecular Evidences from the African West Coast (Angola and Equatorial Guinea)

Background Plasmodium vivax shows a small prevalence in West and Central Africa due to the high prevalence of Duffy negative people. However, Duffy negative individuals infected with P. vivax have been reported in areas of high prevalence of Duffy positive people who may serve as supply of P. vivax strains able to invade Duffy negative erythrocytes. We investigated the presence...

Effect of new and conventional technological processes on the terroir marker 87Sr/86Sr

. Monteiro , R. Bruno de Sousa, A.S. Curvelo-Garcia , S. Catarino , J. Int. Sci. Vigne Vin , 48 ( 1 ), 21 - 29 ( 2014 ) [10] S. Catarino , R. Bruno de Sousa, A.S. Curvelo-Garcia , Origem geogra´fica . In: A.S ... . Catarino , A.S. Curvelo-Garcia , R. Bruno de Sousa, Talanta, 70 , 1073 - 1080 ( 2006 )

Genetic diversity and signatures of selection of drug resistance in Plasmodium populations from both human and mosquito hosts in continental Equatorial Guinea

Cristina Mendes Patrcia Salgueiro Vicenta Gonzalez Pedro Berzosa Agustin Benito Virglio E do Rosrio Bruno de Sousa Jorge Cano Ana Paula Arez Background: In Plasmodium, the high level of genetic

Impact of agr dysfunction on virulence profiles and infections associated with a novel methicillin-resistant Staphylococcus aureus (MRSA) variant of the lineage ST1-SCCmec IV

Background A novel variant of the ST1-SCCmecIV methicillin-resistant Staphylococcus aureus (MRSA) lineage, mostly associated with nosocomial bloodstream infections (BSI), has emerged in Rio de Janeiro. Bacterial biofilm has been considered a major virulence factor in central venous catheter-associated BSI. The mechanisms involved in biofilm formation/accumulation are...

Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Mediterranean region based on mitochondrial sequences

Nova de Lisboa) and Mariana Sousa for their support in imaging and design. Author Contributions Conceptualization: Carolina Bruno de Sousa, Jo?o Varela. Data curation: Carolina Bruno de Sousa, Cymon J ... . Cox, Lu??s Brito, Maria Madalena Pav?o, Ricardo Bermejo, Manuela Parente, Jo?o Varela. 18 / 23 Formal analysis: Carolina Bruno de Sousa, Lu??s Brito, Maria Madalena Pav?o, Ana Ferreira. Funding

Netting barriers to prevent mosquito entry into houses in southern Mozambique: a pilot study

Background One of the best ways to control the transmission of malaria is by breaking the vector-human link, either by reducing the effective population size of mosquitoes or avoiding infective bites. Reducing house entry rates in endophagic vectors by obstructing openings is one simple way of achieving this. Mosquito netting has previously been shown to have this effect. More...

Potential threat of malaria epidemics in a low transmission area, as exemplified by São Tomé and Príncipe

Background Plasmodium falciparum is the major cause of malaria infection in the island of São Tomé, in the Republic of São Tomé and Príncipe (STP), with an incidence of 40 - 50% before 2004. Since 2004, through the coordination of the Ministry of Health of STP and their Centro Nacional de Endemias (CNE), an integrated malaria control programme has been intensively deployed on the...

Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy

Elsa Lobo 0 Bruno de Sousa Soraia Rosa Paula Figueiredo Lis Lobo Sara Pateira Natercia Fernandes Fatima Nogueira 0 Faculdade de Medicina, Departamento de CienciasFisiologicas, Universidade Eduardo

Synthetic organotelluride compounds induce the reversal of Pdr5p mediated fluconazole resistance in Saccharomyces cerevisiae

Background Resistance to fluconazole, a commonly used azole antifungal, is a challenge for the treatment of fungal infections. Resistance can be mediated by overexpression of ABC transporters, which promote drug efflux that requires ATP hydrolysis. The Pdr5p ABC transporter of Saccharomyces cerevisiae is a well-known model used to study this mechanism of antifungal resistance...

Therapeutic Potential of Caspofungin Combined with Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia: A Pilot Study in Mice

Pneumocystis pneumonia (PcP) is a major cause of mortality and morbidity in immunocompromised patients. There are limited alternative therapeutic choices to trimethoprim-sulfamethoxazole (TMP-SMX) which is the standard first line therapy/prophylaxis for PcP. The efficacy of low doses of caspofungin and caspofungin in association with TMP-SMX standard-prophylactic dose was...

What influences national and foreign physicians’ geographic distribution? An analysis of medical doctors’ residence location in Portugal

Bruno de Sousa 0 Cludia Conceio 0 International Public Health and Biostatistics Unit, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa and Centre for Malaria and Tropical Diseases

Why do some physicians in Portuguese-speaking African countries work exclusively for the private sector? Findings from a mixed-methods study

Background Despite the growing interest in the private health sector in low- and middle-income countries, little is known about physicians working outside the public sector. The present work adopts a mixed-methods approach to explore characteristics, working patterns, choices, and motivations of the physicians working exclusively for the private sector in the capital cities of...