Advanced search    

Search: authors:"Carlo Pozzilli"

17 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Correction to: Management of pregnancy-related issues in multiple sclerosis patients: the need for an interdisciplinary approach

The original version contained a mistake. The authors have specified only in a few paragraphs that all the contents of the paper are meant for Copaxone but not for unbranded glatiramer acetate, Authors ask to add the specification of Copaxone or branded glatiramer acetate everytime.

Efficacy of fingolimod and interferon beta-1b on cognitive, MRI, and clinical outcomes in relapsing–remitting multiple sclerosis: an 18-month, open-label, rater-blinded, randomised, multicentre study (the GOLDEN study)

, Montichiari (Brescia), Italy, (5) Carlo Pozzilli and Valentina Bianchi, Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy, (6) Angelo Ghezzi and Marco Roscio, Neurology II

The Clinical Relevance of Force Platform Measures in Multiple Sclerosis: A Review

Prosperini and Carlo Pozzilli. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided

Natalizumab in the pediatric MS population: results of the Italian registry

Background Natalizumab is a promising option for pediatric multiple sclerosis (MS) patients with active evolution and a poor response to Interferon-beta or Glatiramer Acetate. However, no data are available in large cohorts of patients and after a long-term follow up. Our study was planned to shed lights on this topic. Methods A registry was established in 2007 in Italy to...

Oral Dalfampridine Improves Standing Balance Detected at Static Posturography in Multiple Sclerosis

We report a 14-week post-marketing experience on 20 patients with multiple sclerosis (MS) who started prolonged-release (PR) oral dalfampridine 10 mg twice daily according to European Medicine Agency criteria. They underwent serial static posturography assessments and the dizziness handicap inventory (DHI) to investigate whether PR dalfampridine could impact standing balance and...

Prevalence of multiple sclerosis in the Lazio region, Italy: use of an algorithm based on health information systems

, Flavia Mayer (Department of Epidemiology, Lazio Regional Health Service, Rome, Italy). Manuela Giuliani, Donatella Gramaglia, Carlo Pozzilli (S Andrea Hospital, Sapienza University, Rome, Italy). Chiara De

Emerging oral treatments in multiple sclerosis – clinical utility of cladribine tablets

Emerging oral treatments in multiple sclerosis – clinical utility of cladribine tablets Claudio Gasperini1, Serena Ruggieri2, Carlo Pozzilli21Department of Neurosciences, S Camillo Forlanini Hospital, Rome, Italy; 2Department of Neurological Sciences, University of Rome “La Sapienza”, ItalyAbstract: Multiple sclerosis (MS) is a chronic inflammatory disorder of the central...

The Use of Immunosuppressant Therapy for Multiple Sclerosis in Italy: A Multicenter Retroprospective Study

groups: Bayer Schering; Merck Serono; Biogen Idec. Carlo Pozzilli declared receipt of grants and contracts by: Merck Serono; Biogen Idec. He declared also receipt of honoraria or consultation fees by

Assessing the Correlation between Grey and White Matter Damage with Motor and Cognitive Impairment in Multiple Sclerosis Patients

Background Multiple sclerosis (MS) is characterized by demyelinating and degenerative processes within the central nervous system. Unlike conventional MRI,new advanced imaging techniques improve pathological specificity and better highlight the relationship between anatomical damage and clinical impairment. Objective To investigate the relationship between clinical disability and...

Safety of the first dose of fingolimod for multiple sclerosis: results of an open-label clinical trial

Pozzilli 4 Giancarlo Comi 3 Alessandra Lugaresi Renato Turrini Debora Raimondi Antonio Uccelli 0 Giovanni Luigi Mancardi 0 on behalf of the EAP Investigators 0 Department of Neuroscience, Rehabilitation

Evidence of Impaired Brain Activity Balance after Passive Sensorimotor Stimulation in Multiple Sclerosis

Objectives Examination of sensorimotor activation alone in multiple sclerosis (MS) patients may not yield a comprehensive view of cerebral response to task stimulation. Additional information may be obtained by examining the negative BOLD response (deactivation). Aim of this work was to characterize activation and deactivation patterns during passive hand movements in MS patients...

Management of breakthrough disease in patients with multiple sclerosis: when an increasing of Interferon beta dose should be effective?

Background In daily clinical setting, some patients affected by relapsing-remitting Multiple Sclerosis (RRMS) are switched from the low-dose to the high-dose Interferon beta (IFNB) in order to achieve a better control of the disease. Purpose In this observational, post-marketing study we reported the 2-year clinical outcomes of patients switched to the high-dose IFNB; we also...

Neutralizing antibodies explain the poor clinical response to Interferon beta in a small proportion of patients with Multiple Sclerosis: a retrospective study

Background Neutralizing antibodies (NAbs) against Interferon beta (IFNβ) are reported to be associated with poor clinical response to therapy in multiple sclerosis (MS) patients. We aimed to quantify the contribution of NAbs to the sub-optimal response of IFNβ treatment. Methods We studied the prevalence of NAbs in MS patients grouped according to their clinical response to IFN...

Paternal therapy with disease modifying drugs in multiple sclerosis and pregnancy outcomes: a prospective observational multicentric study

Background Most of Multiple Sclerosis (MS) patients undergo disease modifying drug (DMD) therapy at childbearing age. The objective of this prospective, collaborative study, was to assess outcomes of pregnancies fathered by MS patients undergoing DMD. Methods Structured interviews on pregnancies fathered by MS patients gathered in the Italian Pregnancy Dataset were collected...

Pregnancy and fetal outcomes after Glatiramer Acetate exposure in patients with multiple sclerosis: a prospective observational multicentric study

Background Only few studies have assessed safety of in utero exposure to glatiramer acetate (GA). Following a previous study assessing the safety of interferon beta (IFNB) pregnancy exposure in multiple sclerosis (MS), we aimed to assess pregnancy and fetal outcomes after in utero exposure to GA, using the same dataset, with a specific focus on the risk of spontaneous abortion...

Epidural analgesia and cesarean delivery in multiple sclerosis post-partum relapses: the Italian cohort study

Background Few studies have systematically addressed the role of epidural analgesia and caesarean delivery in predicting the post-partum disease activity in women with Multiple Sclerosis (MS). The objective of this study was to assess the impact of epidural analgesia (EA) and caesarean delivery (CD) on the risk of post-partum relapses and disability in women with MS. Methods In...