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Search: authors:"Carmen Rotte"

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Manfred Eigen: the realization of his vision of Biophysical Chemistry

Manfred Eigen turned 90 on May 9th, 2017. He celebrated with a small group of colleagues and friends on behalf of the many inspired by him over his lifetime—whether scientists, artists, or philosophers. A small group of friends, because many—who by their breakthroughs have changed the face of science in different research areas—have already died. But it was a special day, devoted...

Pyruvate : NADP Oxidoreductase from the Mitochondrion of Euglena gracilis and from the Apicomplexan Cryptosporidium parvum: A Biochemical Relic Linking Pyruvate Metabolism in Mitochondriate and Amitochondriate Protists

Most eukaryotes perform the oxidative decarboxylation of pyruvate in mitochondria using pyruvate dehydrogenase (PDH). Eukaryotes that lack mitochondria also lack PDH, using instead the O2-sensitive enzyme pyruvate : ferredoxin oxidoreductase (PFO), which is localized either in the cytosol or in hydrogenosomes. The facultatively anaerobic mitochondria of the photosynthetic protist...

A Genome Phylogeny for Mitochondria Among α-Proteobacteria and a Predominantly Eubacterial Ancestry of Yeast Nuclear Genes

Analyses of 55 individual and 31 concatenated protein data sets encoded in Reclinomonas americana and Marchantia polymorpha mitochondrial genomes revealed that current methods for constructing phylogenetic trees are insufficiently sensitive (or artifact-insensitive) to ascertain the sister of mitochondria among the current sample of eight α-proteobacterial genomes using...