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Human adenovirus among hospitalized children with respiratory tract infections in Beijing, China, 2017–2018

help us to understand the extent of genetic variation and any potential recombination that has occurred in the strains referred to above. Notes Lihong Yao, Chao Wang and Tianli Wei contributed equally

Clinical diagnosis and mutation analysis of four Chinese families with succinic semialdehyde dehydrogenase deficiency

Succinic semialdehyde dehydrogenase (SSADH) deficiency is a rare autosomal recessively-inherited defect of γ-aminobutyric acid (GABA) metabolism. The absence of SSADH, which is encoded by aldehyde dehydrogenase family 5 member A1 (ALDH5A1) gene, leads to the accumulation of GABA and γ-hydroxybutyric acid (GHB). Few cases with SSADH deficiency were reported in China. In this study...

Safety and efficacy of bone marrow-derived cells therapy on cardiomyopathy: a meta-analysis

-systolic volume MACE Major adverse cardiovascular event MlHFQ Minnesota Living with Heart Failure Questionnaire SPECT Single-photon emission-computed tomography WMD Weighted mean difference Chao Wang and

Development and validation of a risk prediction score for severe acute pancreatitis

, Vincent Zimmer†4, 5, Evangelos Kontopantelis†6, 7, Simon Stock8, Maddalena Zippi†9, Chao Wang†10 and Mengtao Zhou11Email author †Contributed equally Journal of Translational Medicine201917:146 https ... application of it on admission may improve clinical care and management strategies in acute pancreatitis. Notes Wandong Hong, Vincent Zimmer, Evangelos Kontopantelis, Maddalena Zippi and Chao Wang

Subloading Surface Model and Experimental Study of Coal Failure under Cyclic Loading

The fatigue damage of rock is an important factor affecting the stability of rock structure. In this paper, the mechanical response of coal under cyclic loading was studied. In order to accurately describe the deformation characteristics of coal under cyclic loading, an elastic-plastic model of coal based on the theory of subloading surface was established and verified by...

Parameter study of sound energy distribution in cuboid extra-large spaces

The aim of this paper is to explore the sound energy distribution in cuboid extra-large spaces. The surface absorption and height are studied as the parameters using the image method. Air absorption is also discussed in this paper. The results show that the difficulty of reducing the noise increases with the increasing volume in extra-large spaces. Even if the ratio between the...

Development of a novel autonomous lower extremity exoskeleton robot for walking assistance

Today, exoskeletons are widely applied to provide walking assistance for patients with lower limb motor incapacity. Most existing exoskeletons are under-actuated, resulting in a series of problems, e.g., interference and unnatural gait during walking. In this study, we propose a novel intelligent autonomous lower extremity exoskeleton (Auto-LEE), aiming at improving the user...

Friend and POI recommendation based on social trust cluster in location-based social networks

Friend and point-of-interest (POI) recommendation are two primary individual services in location-based social networks (LBSNs). Major social platforms such as Foursquare and Instagram are all capable of recommending friends or POIs to individuals. However, most of these social websites make recommendations only based on similarity, popularity, or geographical influence; social...

Anti-H7N9 avian influenza A virus activity of interferon in pseudostratified human airway epithelium cell cultures

Since H7N9 influenza A virus (H7N9) was first reported in 2013, five waves of outbreaks have occurred, posing a huge threat to human health. In preparation for a potential H7N9 epidemic, it is essential to evaluate the efficacy of anti-H7N9 drugs with an appropriate model. Well-differentiated pseudostratified human airway epithelium (HAE) cells were grown at the air–liquid...

Genetic Algorithm-Based Variable Value Control Method for Solving the Ground Target Attacking Weapon-Target Allocation Problem

Xi’an Institute of High-Tech, Xi’an 710025, China Correspondence should be addressed to Chao Wang; moc.361@51067901781 Received 17 October 2018; Accepted 4 February 2019; Published 17 February 2019 ... Academic Editor: Anna M. Gil-Lafuente Copyright © 2019 Chao Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use

SLC25A22 promotes proliferation and metastasis by activating MAPK/ERK pathway in gallbladder cancer

SLC25A22, a member of mitochondrial carrier system (MCS) family encoding a mitochondrial glutamate transporter, has been reported to have vital roles in promoting proliferation and migration in cancer. Gallbladder cancer (GBC) is the most common biliary tract malignancy and has a poor prognosis. We aimed to determine the expression and function of SLC25A22 in GBC...

Concrete Compression Test Data Estimation Based on a Wavelet Neural Network Model

Firstly, a genetic algorithm (GA) and simulated annealing (SA) optimized fuzzy c-means clustering algorithm (FCM) was proposed in this paper, which was developed to allow for a clustering analysis of the massive concrete cube specimen compression test data. Then, using an optimized error correction time series estimation method based on the wavelet neural network (WNN), a...

Experimental Investigation of the Effect of Ice Blockage on Propeller Hydrodynamic Performance

Engineering University, Harbin 150001, China Correspondence should be addressed to Chao Wang; nc.ude.uebrh@608oahcgnaw Received 2 October 2018; Accepted 13 December 2018; Published 3 January 2019 Academic

Efficacy and safety of Tongfu powder in acute pancreatitis patients with gastrointestinal dysfunction: a clinical trial

Efficacy and safety of Tongfu powder in acute pancreatitis patients with gastrointestinal dysfunction: a clinical trial Bin Miao, Feng-Wu Li, Shu-Wen Zhang, Hong Wang, Wen-Jie Qi, Chao Wang

Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through β-catenin/Erk/Akt signaling in gastric cancer

Enzymatically inactive chitinase-like protein CHI3L1 drives inflammatory response and promotes tumor progression. However, its role in gastric cancer (GC) tumorigenesis and metastasis has not yet been fully elucidated. We determined the significance of CHI3L1 expression in patients with GC. We also explored an as-yet unknown receptor of CHI3L1 and investigated the involved...

Solving a Large-Scale Multi-Depot Vehicle Scheduling Problem in Urban Bus Systems

This study proposes an improved model and algorithm for the large-scale multi-depot vehicle scheduling problem (MDVSP) with departure-duration restrictions. In this study, the time-space network is applied to model the large-scale MDVSP. Considering that crews usually change shifts in the depot, departure-duration restrictions are added to the classic set-partitioning model to...

MiR-494-3p promotes PI3K/AKT pathway hyperactivation and human hepatocellular carcinoma progression by targeting PTEN

-chao Wang HuiYao Ke-zhu Hou Fang-ming Gu Xuan-fu Xu Recent studies have shown that miR-494-3p is oncogene and has a central role in many solid tumors; however, the role of miR-494-3p in the progression ... Foundation of China, No.: 81472689. Author Contributions Ke-zhu Hou, Fang-ming Gu and Xuan-fu Xu conceived the study and designed the experiments. Yuan-ping Tao, Meng-chao Wang and Hui Yao performed the

Molecular mechanisms of tannin accumulation in Rhus galls and genes involved in plant-insect interactions

For galling aphids and their hosts, tannins are crucial for plant-insect interactions and for protecting the host plant from herbivory. Due to their peculiar chemical characteristics, tannins from plant galls have been used for medical and chemical purposes for more than 2000 years. In this study, hydrolyzable tannin concentrations in galls increased from gall initiation (38.34...