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Search: authors:"Charles E. Hammond"

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Journal of Surfactants and Detergents: The Legacy and Future for Formulators

and affiliations Charles EHammond Editorial First Online: 19 June 2017 3 Shares 748 Downloads Open image in new window It is hard to believe it was June 2003 when we had an S&D

Inhibition of gastric H,K-ATPase activity and gastric epithelial cell IL-8 secretion by the pyrrolizine derivative ML 3000

Background ML 3000 ([2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid) is an inhibitor of both cyclooxygenase and 5-lipoxygenase in vitro, and shows promise as a novel non-steroidal anti-inflammatory drug (NSAID). Unlike conventional NSAIDs which are associated with gastric ulcerogenic effects, ML 3000 causes little or no damage to the gastric...