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Search: authors:"Charlie Bridgewood"

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The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man

ObjectiveThe heterodimeric IL-12 family member cytokines including, IL-12, IL-23, IL-27, and IL-35 and have multiple roles in regulating innate and adaptive immunity with crucial functions in inflammatory disorders such as psoriasis. Chain pairing promiscuity is a feature of the IL-12 family. Recently, based on murine data, a new family member, IL-39, was proposed, consisting of...