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45 papers found.
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B-decay anomalies and scalar leptoquarks in unified Pati-Salam models from noncommutative geometry

Abstract Motivated by possible scalar-leptoquark explanations of the recently reported B-decay anomalies, we investigate whether the required leptoquarks can be accommodated within models based on noncommutative geometry (NCG). The models considered have the gauge structure of Pati-Salam models, SU(4) × SU(2)L × SU(2)R, with gauge coupling unification at a single scale. In one of...

Study on the early detection of gastric cancer based on discrete wavelet transformation feature extraction of FT-IR spectra combined with probability neural network

Lu 2 Cun-Gui Cheng 3 Xiao-Chen Sun 4 0 Faculty of Life Science and Chemical Engineering, Huaiyin Institute of Technology , Huaian , China 1 National Special Superfine Powder Engineering Center, Nanjing

MetaBinG2: a fast and accurate metagenomic sequence classification system for samples with many unknown organisms

Many methods have been developed for metagenomic sequence classification, and most of them depend heavily on genome sequences of the known organisms. A large portion of sequencing sequences may be classified as unknown, which greatly impairs our understanding of the whole sample. Here we present MetaBinG2, a fast method for metagenomic sequence classification, especially for...

Study on the early detection of gastric cancer based on discrete wavelet transformation feature extraction of FT-IR spectra combined with probability neural network

This paper introduces a new method for the early detection of gastric cancer using a combination of feature extraction based on discrete wavelet transformation (DWT) for horizontal attenuated total reflectance–Fourier transform infrared spectroscopy (HATR–FT-IR) and classification using probability neural network (PNN). 344 FT-IR spectra were collected from 172 pairs of fresh...

Elastic pseudospin transport for integratable topological phononic circuits

, Fu-Kang Liu, Xiao-Chen Sun, Zheng Li, Ming-Hui Lu, Xiao-Ping Liu & Yan-Feng ChenCollaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, 210093, ChinaSi-Yuan Yu, Cheng ... • PubMed • Google Scholar Search for Xiao-Chen Sun in:Nature Research journals • PubMed • Google Scholar Search for Zheng Li in:Nature Research journals • PubMed • Google Scholar Search for Hai-Zhou Lu

Photooxygenations and Self-Sensitizations of Naphthylamines: Efficient Access to Iminoquinones

A series of spiro [fluorene-9,7′-dibenzo[c,h]acridine]-5′-one (SFDBAO) derivatives have been concisely and cleanly obtained by exposure to sunlight without external photosensitizers in the higher yields than that when using a UV lamp. An interesting autocatalyst and self-sensitive procedure have been proposed to explain the effective photooxygenation. SFDBAO derivatives exhibit...

Photooxygenations and Self-Sensitizations of Naphthylamines: Efficient Access to Iminoquinones

A series of spiro [fluorene-9,7′-dibenzo[c,h]acridine]-5′-one (SFDBAO) derivatives have been concisely and cleanly obtained by exposure to sunlight without external photosensitizers in the higher yields than that when using a UV lamp. An interesting autocatalyst and self-sensitive procedure have been proposed to explain the effective photooxygenation. SFDBAO derivatives exhibit...

Photooxygenations and Self-Sensitizations of Naphthylamines: Efficient Access to Iminoquinones

A series of spiro [fluorene-9,7′-dibenzo[c,h]acridine]-5′-one (SFDBAO) derivatives have been concisely and cleanly obtained by exposure to sunlight without external photosensitizers in the higher yields than that when using a UV lamp. An interesting autocatalyst and self-sensitive procedure have been proposed to explain the effective photooxygenation. SFDBAO derivatives exhibit...

The corneal epitheliotrophic abilities of lyophilized powder form human platelet lysates

. Funding acquisition: Wei-Li Chen. Methodology: Chia-Ju Lu, Yi-Chen Sun. Project administration: Chia-Ju Lu, Szu-Yuan Lin. Resources: Yi-Chen Sun, Szu-Yuan Lin. Writing ± original draft: Lily Wei Chen

A mitochondria-targeting artemisinin derivative with sharply increased antitumor but depressed anti-yeast and anti-malaria activities

Zhou AuthorsSearch for Chen Sun in:Nature Research journals • PubMed • Google ScholarSearch for Yu Cao in:Nature Research journals • PubMed • Google ScholarSearch for Pan Zhu in:Nature Research journals

FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy

Oxidative stress has been implicated in triggering granulosa cell (GC) death during follicular atresia. Recent studies suggested that follicle-stimulating hormone (FSH) has a pivotal role in protecting GCs from oxidative injury, although the exact mechanism remains largely unknown. Here, we report that FSH promotes GC survival by inhibiting oxidative stress-induced mitophagy. The...

H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing

Aims. The study was designed to explore whether hydrogen sulphide (H2S) and nitric oxide (NO) generation changed in D-galactose- (D-gal-) induced ageing, the possible effects of exogenous H2S supplementation, and related mechanisms. Results. In D-gal-induced senescent mice, both H2S and NO levels in the heart, liver, and kidney tissues were decreased significantly. A similar...

H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing

Aims. The study was designed to explore whether hydrogen sulphide (H2S) and nitric oxide (NO) generation changed in D-galactose- (D-gal-) induced ageing, the possible effects of exogenous H2S supplementation, and related mechanisms. Results. In D-gal-induced senescent mice, both H2S and NO levels in the heart, liver, and kidney tissues were decreased significantly. A similar...

Optimized polymer enhanced foam flooding for ordinary heavy oil reservoir after cross-linked polymer flooding

A successful cross-linked polymer flooding has been implemented in JD reservoir, an ordinary heavy oil reservoir with high permeability zones. For all that, there are still significant volumes of continuous oil remaining in place, which can not be easily extracted due to stronger vertical heterogeneity. Considering selective plugging feature, polymer enhanced foam (PEF) flooding...

Inhibition of Rac1 GTPase activity affects porcine oocyte maturation and early embryo development

Mammalian oocyte asymmetric division relies on the eccentric positioning of the spindle, resulting in the polar body formation. Small signaling G protein Rac1 is a member of GTPases, which regulates a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. However, effects of Rac1 on the porcine...

Protective Effects of Hydrogen Sulfide in the Ageing Kidney

Aims. The study aimed to examine whether hydrogen sulfide (H2S) generation changed in the kidney of the ageing mouse and its relationship with impaired kidney function. Results. H2S levels in the plasma, urine, and kidney decreased significantly in ageing mice. The expression of two known H2S-producing enzymes in kidney, cystathionine γ-lyase (CSE) and cystathionine-β-synthase...

Comparison of corneal epitheliotrophic capacities among human platelet lysates and other blood derivatives

Purpose To evaluate the corneal epitheliotropic abilities of two commercialized human platelet lysates (HPLs) and to compare the results with other blood derivatives, including human peripheral serum (HPS) and bovine fetal serum (FBS). Methods In vitro, human corneal epithelial cells were incubated in various concentrations (0%, 3%, 5% and 10%) of blood derivatives. Two...

Acoustic topological insulator and robust one-way sound transport

, Nanjing University, Nanjing, Jiangsu 210093, ChinaCheng He, Xu Ni, Hao Ge, Xiao-Chen Sun, Yan-Bin Chen, Ming-Hui Lu, Xiao-Ping Liu & Yan-Feng ChenCollaborative Innovation Center of Advanced Microstructures ... in:Nature Research journals • PubMed • Google ScholarSearch for Hao Ge in:Nature Research journals • PubMed • Google ScholarSearch for Xiao-Chen Sun in:Nature Research journals • PubMed • Google ScholarSearch

Melamine Induces Oxidative Stress in Mouse Ovary

Melamine is a nitrogen heterocyclic triazine compound which is widely used as an industrial chemical. Although melamine is not considered to be acutely toxic with a high LD50 in animals, food contaminated with melamine expose risks to the human health. Melamine has been reported to be responsible for the renal impairment in mammals, its toxicity on the reproductive system...

miR-221 Promotes Epithelial-Mesenchymal Transition through Targeting PTEN and Forms a Positive Feedback Loop with β-catenin/c-Jun Signaling Pathway in Extra-Hepatic Cholangiocarcinoma

Extrahepatic cholangiocarcinoma (EHCC) is a refractory malignancy with poor prognosis due to its early invasion, metastasis and recurrence after operation. Therefore, understanding the mechanisms of invasion and metastasis is the key to the development of new and effective therapeutic strategies for EHCC. In the present study we demonstrated that miR-221 promoted EHCC invasion...