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Impaired function of tendon-derived stem cells in experimental diabetes mellitus rat tendons: implications for cellular mechanism of diabetic tendon disorder

BackgroundPatients with diabetes mellitus (DM) often suffered with many musculoskeletal disorders, such as tendon rupture and tendinopathy. However, the understanding of the pathogenesis of these alternations is limited. This study was designed to investigate the role of tendon-derived stem cells (TDSCs) in histopathological alterations of DM tendons.MethodsForty-two SD rats were...

Research on the effect of image size on real-time performance of robot vision positioning

Technology and Art, Harbin Institute of Technology. His research interests include game development, virtual reality, and intelligent robotics. Chen Wang was born in Harbin, Heilongjiang, People’s Republic of

Hematocrit and the incidence of stroke: a prospective, population-based cohort study

Hematocrit and the incidence of stroke: a prospective, population-based cohort study Renling Yang,1,2 Anxin Wang,3–6 Li Ma,2 Zhaoping Su,7 Shuohua Chen,8 Yilong Wang,3–6 Shouling Wu,8 Chen Wang1,2 1Department of General Practice, School of General Practice and Continuing Education, Capital Medical University, Beijing, China; 2Department of General Practice, Beijing Tiantan...

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer

PurposeMetarrestin is a first-in-class small molecule clinical candidate capable of disrupting the perinucleolar compartment, a subnuclear structure unique to metastatic cancer cells. This study aims to define the pharmacokinetic (PK) profile of metarrestin and the pharmacokinetic/pharmacodynamic relationship of metarrestin-regulated markers.MethodsPK studies included the...

Interaction between CD177 and platelet endothelial cell adhesion molecule-1 downregulates membrane-bound proteinase-3 (PR3) expression on neutrophils and attenuates neutrophil activation induced by PR3-ANCA

A recent study found that CD177 served as a receptor of membrane-bound proteinase-3 (mPR3) in a subset of neutrophils. Furthermore, CD177 has been identified as a high-affinity heterophilic binding partner for the endothelial cell platelet endothelial cell adhesion molecule-1 (PECAM-1). The current study aimed to investigate whether the interaction between PECAM-1 and CD177 could...

A Review of Point Feature Based Medical Image Registration

 WangCai MengJun-Chen Wang Open Access Review First Online: 24 August 2018 421 Downloads Part of the following topical collections:overview Abstract Point features, as the basis of lines ... will experience an upcoming explosion.   Notes Authors’ Contributions Cai Meng was directed the entire trial; Shao-Ya Guan wrote the manuscript; Tian-Miao Wang and Jun-Chen Wang assisted in

LANTHANUM ELEMENT INDUCED IMBALANCE OF MINERAL NUTRIENTS, HSP 70 PRODUCTION AND DNA-PROTEIN CROSSLINK, LEADING TO HORMETIC RESPONSE OF CELL CYCLE PROGRESSION IN ROOT TIPS OF VICIA FABA L. SEEDLINGS

ROOT TIPS OF VICIA FABA L. SEEDLINGS Authors Chengrun Wany, Cuie Shi, Ling Liu, Chen Wang, Wei Qiao, Zhimang Gu, and Xiaorong Wang This article is available in Dose-Response: An International Journal

A note on convergence of weighted sums of random variables

Under uniform integrability condition, some Weak Laws of large numbers are established for weighted sums of random variables generalizing results of Rohatgi, Pruitt and Khintchine. Some Strong Laws of Large Numbers are proved for weighted sums of pairwise independent random variables generalizing results of Jamison, Orey and Pruitt and Etemadi.

Cylindricity Error Evaluation Based on an Improved Harmony Search Algorithm

The cylindricity error is one of the basic form errors in mechanical parts, which greatly influences the assembly accuracy and service life of relevant parts. For the minimum zone method (MZM) in international standards, there is no specific formula to calculate the cylindricity error. Therefore, the evaluation methods of the cylindricity error under the MZM have been widely...

Is exclusion of leukocytes from platelet-rich plasma (PRP) a better choice for early intervertebral disc regeneration?

BackgroundPlatelet-rich plasma (PRP) is becoming a promising strategy to treat early intervertebral disc degeneration (IDD) in clinics. Pure PRP without leukocytes (P-PRP) may decrease the catabolic and inflammatory changes in the early degenerated intervertebral discs. The aim of this study was to investigate the effects of P-PRP on nucleus pulposus-derived stem cells (NPSCs...

DPP-4 Inhibitor Sitagliptin Improves Cardiac Function and Glucose Homeostasis and Ameliorates β-Cell Dysfunction Together with Reducing S6K1 Activation and IRS-1 and IRS-2 Degradation in Obesity Female Mice

Female Mice Shigang Qiao,1,2,3 Guofang Mao,4 Hua Li,2 Zhimin Ma,4 Lei Hong,1 Huiling Zhang,3 Chen Wang,1,2 and Jianzhong An1 1Institute of Clinical Medicine Research, The Affiliated Suzhou Hospital of ... Hospital, No. 1 Lijiang Road, Suzhou 215153, China Correspondence should be addressed to Chen Wang; moc.621@cw_yycjkzs and Jianzhong An; moc.621@zja_yycjkzs Received 9 April 2018; Revised 8 June 2018

CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing

and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USADavid C. Marciano, Chen Wang, Christophe Herman & Olivier LichtargeQuantitative and Computational Biosciences, Baylor College of ... for Benu Atri in:Nature Research journals • PubMed • Google Scholar Search for Rachel E. Bosserman in:Nature Research journals • PubMed • Google Scholar Search for Chen Wang in:Nature Research

Clinical effect of MUC1 and its relevance to BRAF V600E mutation in papillary thyroid carcinoma: a case–control study

, Dan-Rong Ye, Yi-Han Sun, Xiao-Hua Zhang, Ou-Chen Wang, En-Dong Chen, Ye-Feng Cai Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang

Research on Bogie Frame Lateral Instability of High-Speed Railway Vehicle

17 November 2017; Revised 25 March 2018; Accepted 19 April 2018; Published 29 May 2018 Academic Editor: Mario Terzo Copyright © 2018 Chen Wang et al. This is an open access article distributed under

Research on Bogie Frame Lateral Instability of High-Speed Railway Vehicle

17 November 2017; Revised 25 March 2018; Accepted 19 April 2018; Published 29 May 2018 Academic Editor: Mario Terzo Copyright © 2018 Chen Wang et al. This is an open access article distributed under

IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury

• PubMed • Google Scholar Search for Lo-Hsin Dai in:Nature Research journals • PubMed • Google Scholar Search for Wan-Chen Wang in:Nature Research journals • PubMed • Google Scholar Search for Ya-Jen

Acute Physiological and Psychological Effects of Qigong Exercise in Older Practitioners

. Tze-Taur Wei, Chen-Chen Wang, WanChen Chen, and Yu-Min Wang participated in the literature searches and contributed to data collection of the study. Song-Yen Tsai contributed to revisions and the final

Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration

transferase dUTP nick end labeling; WISH, wholemount in situ hybridization. COMPLIANCE WITH ETHICS GUIDELINES Xiao-Shuai Han, Chen Wang, Fang-hao Guo, Shuang Huang, YongWen Qin, Xian-Xian Zhao and Qing Jing