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Ultra-stable Electrochemical Sensor for Detection of Caffeic Acid Based on Platinum and Nickel Jagged-Like Nanowires

Electrochemical sensors have the high sensitivity, fast response, and simple operation for applications in biological, medical, and chemical detection, but limited by the poor stability and high cost of the electrode materials. In this work, we used PtNi lagged-like nanowire for caffeic acid (CA) electrochemical detection. The removal of outer layer Ni during reaction process...

Cytokine Imbalance as a Common Mechanism in Both Psoriasis and Rheumatoid Arthritis

conceived and designed the experiments. Cheng Lu, Xuyan Niu, Yanping Bai, and Cheng Xiao performed the experiments. Yong Tan, Xuyan Niu, Chunyan Jiang, and Yang Wang analyzed the data. Aiping Lu and Cheng ... Xiao contributed reagents/materials/analysis tools. Yong Tan, Qiu Qi, and Cheng Lu wrote the paper. Yong Tan, Qiu Qi, and Cheng Lu contributed equally to this work. Acknowledgments T his study was

A protein fragment derived from DNA-topoisomerase I as a novel tumour-associated antigen for the detection of early stage carcinoma

Background:The production of autoantibodies against tumour-associated antigens (TAAs) is believed to reflect greater immunologic reactivity in cancer patients and enhanced immune surveillance for cancer cells. Over the past few decades, a number of different TAAs and their corresponding autoantibodies have been investigated. However, positive frequency of autoantibody detection...

Comparative genomics of parasitic silkworm microsporidia reveal an association between genome expansion and host adaptation

Background Microsporidian Nosema bombycis has received much attention because the pébrine disease of domesticated silkworms results in great economic losses in the silkworm industry. So far, no effective treatment could be found for pébrine. Compared to other known Nosema parasites, N. bombycis can unusually parasitize a broad range of hosts. To gain some insights into the...