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-Nearest Neighbor Intervals Based AP Clustering Algorithm for Large Incomplete Data

2Army Aviation Institute, Beijing 101123, China Received 15 January 2015; Accepted 2 March 2015 Academic Editor: Hui Zhang Copyright © 2015 Cheng Lu et al. This is an open access article distributed

-Nearest Neighbor Intervals Based AP Clustering Algorithm for Large Incomplete Data

2Army Aviation Institute, Beijing 101123, China Received 15 January 2015; Accepted 2 March 2015 Academic Editor: Hui Zhang Copyright © 2015 Cheng Lu et al. This is an open access article distributed

A Large Group Decision Making Approach Based on TOPSIS Framework with Unknown Weights Information

Large group decision making considering multiple attributes is imperative in many decision areas. The weights of the decision makers (DMs) is difficult to obtain for the large number of DMs. To cope with this issue, an integrated multiple-attributes large group decision making framework is proposed in this article. The fuzziness and hesitation of the linguistic decision variables...

A Metabolomics Profiling Study in Hand-Foot-and-Mouth Disease and Modulated Pathways of Clinical Intervention Using Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

Academic Editor: Wei Jia Copyright © 2013 Cheng Lu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

A Metabolomics Profiling Study in Hand-Foot-and-Mouth Disease and Modulated Pathways of Clinical Intervention Using Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

Academic Editor: Wei Jia Copyright © 2013 Cheng Lu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

A Neglected Issue on Sexual Well-Being following Breast Cancer Diagnosis and Treatment among Chinese Women

Background Changes to sexual well-being can be one of the most problematic quality of life issues following the diagnosis and treatment of breast cancer. The objectives of the present study were to evaluate changes to sexual well-being following breast cancer, to expand upon the existing body of knowledge pertaining to breast cancer and sexuality, and to provide the necessary...

A combined experimental-numerical approach for determining mechanical properties of aluminum subjects to nanoindentation

A crystal plasticity finite element method (CPFEM) model has been developed to investigate the mechanical properties and micro-texture evolution of single-crystal aluminum induced by a sharp Berkovich indenter. The load-displacement curves, pile-up patterns and lattice rotation angles from simulation are consistent with the experimental results. The pile-up phenomenon and lattice...

A holistic approach to visualizing business models for the internet of things

The Internet of Things (IoT) promises huge potential economic benefits. However, current IoT applications are in their infancy and the full potential of possible business opportunities is yet to be discovered. To help realize these economic benefits, workable business models are required that show where opportunities exist. In this article we describe the Business DNA Model - a...

A new insight into ductile fracture of ultrafine-grained Al-Mg alloys

AffiliationsSchool of Mechanical, Materials & Mechatronics Engineering, University of Wollongong, Wollongong, NSW 2500, AustraliaHailiang Yu, A. Kiet Tieu, Cheng Lu, Xiong Liu, Mao Liu & Ajit GodboleElectron ... Hailiang Yu in:Nature Research journals • PubMed • Google ScholarSearch for A. Kiet Tieu in:Nature Research journals • PubMed • Google ScholarSearch for Cheng Lu in:Nature Research journals • PubMed • Google

A protein fragment derived from DNA-topoisomerase I as a novel tumour-associated antigen for the detection of early stage carcinoma

Background:The production of autoantibodies against tumour-associated antigens (TAAs) is believed to reflect greater immunologic reactivity in cancer patients and enhanced immune surveillance for cancer cells. Over the past few decades, a number of different TAAs and their corresponding autoantibodies have been investigated. However, positive frequency of autoantibody detection...

A systematic review of structured sparse learning

affiliations Lin-bo QiaoBo-feng ZhangJin-shu SuXi-cheng Lu Review First Online: 19 April 2017 293 Downloads 2 Citations Abstract High dimensional data arising from diverse scientific research

Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling by Emilia sonchifolia Extract, a Folklore Medicinal Plant

Medicinal Plant Yu-Hsuan Lan,1 Jo-Hua Chiang,2 Wen-Wen Huang,3 Chi-Cheng Lu,2 Jing-Gung Chung,3 Tian-Shung Wu,1 Jia-Hua Jhan,4 Kuei-Li Lin,5 Shu-Jen Pai,3 Yu-Jen Chiu,6 Minoru Tsuzuki,7,8 and Jai-Sing Yang8,9

Advanced VLSI Architecture Design for Emerging Digital Systems

. Yu-Cheng Fan Qiaoyan Yu Thomas Schumann Ying-Ren Chien Chih-Cheng Lu

Altered molecular repertoire of immune system by renal dysfunction in the elderly: is prediction and targeted prevention in the horizon?

Background Patients on chronic hemodialysis (HD) have impaired cellular and humoral immunity. The percentage of elderly people among the total population in Taiwan is increasing dramatically, and HD is the primary alternative for renal replacement therapy when renal function declines. Activated vitamin D is widely used in HD patients with secondary hyperparathyroidism (SHPT) and...

Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes High Risk for Chronic Kidney Disease in Asian Male with Hypertension–A Meta-Regression Analysis of 98 Observational Studies

Background Associations between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphisms and chronic kidney disease (CKD) have been extensively studied, with most studies reporting that individuals with the D allele have a higher risk. Although some factors, such as ethnicity, may moderate the association between ACE I/D polymorphisms and CKD risk, gender...

Annotation and expression of carboxylesterases in the silkworm, Bombyx mori

Background Carboxylesterase is a multifunctional superfamily and ubiquitous in all living organisms, including animals, plants, insects, and microbes. It plays important roles in xenobiotic detoxification, and pheromone degradation, neurogenesis and regulating development. Previous studies mainly used Dipteran Drosophila and mosquitoes as model organisms to investigate the roles...

Association between MGMT Promoter Methylation and Non-Small Cell Lung Cancer: A Meta-Analysis

and Quality Assessment All the data were independently abstracted by three authors (Changmei Gu, Cheng Lu, and Hao Shi) with the use of standardized data-extraction forms. For each study, the following

Association between P16INK4a Promoter Methylation and HNSCC: A Meta-Analysis of 21 Published Studies

Cheng Lu) as described in the Cochrane Handbook for systematic reviews. Statistical Methods The pooled odds ratios (ORs) and their 95% confidence intervals (CIs) were used to assess the strength of the

Association between RASSF1A Promoter Methylation and Ovarian Cancer: A Meta-Analysis

of interest (three stars). The studies were independently evaluated based on NOS by three reviewers (Cheng Lu, Lilan Yang, and Jiaqiang Xiong). Studies with quality scores greater than or equal to 5

Association between Variants of the Autophagy Related Gene – IRGM and Susceptibility to Crohn’s Disease and Ulcerative Colitis: A Meta-Analysis

BackgroundPolymorphisms in immunity-related GTPase family M (IRGM) gene may be associated with inflammatory bowel disease (IBD) by affecting autophagy. However, the genetic association studies on three common variants in IRGM gene (rs13361189, rs4958847 and rs10065172) have shown inconsistent results. Methodology/ Principal FindingsThe PubMed and Embase were searched up to June 5...