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Room temperature electrofreezing of water yields a missing dense ice phase in the phase diagram

Water can freeze into diverse ice polymorphs depending on the external conditions such as temperature (T) and pressure (P). Herein, molecular dynamics simulations show evidence of a high-density orthorhombic phase, termed ice χ, forming spontaneously from liquid water at room temperature under high-pressure and high external electric field. Using free-energy computations based on...

Large magnetic anisotropy in chemically engineered iridium dimer

Exploring giant magnetic anisotropy in small magnetic nanostructures is of technological merit for information storage. Large magnetic anisotropy energy (MAE) over 50 meV in magnetic nanostructure is desired for practical applications. Here we show the possibility to boost the magnetic anisotropy of the smallest magnetic nanostructure—transition metal dimer. Through systematic...

Detection of Sentinel Lymph Nodes with Near-Infrared Imaging in Malignancies

areas, precise positioning of the tumor and the area of the incision are Huan-Cheng Zeng and Jia-Lin Hu contributed equally to this work. critical factors. In this respect, the biopsy of sentinel lymph

Cardioprotection of tilianin ameliorates myocardial ischemia-reperfusion injury: Role of the apoptotic signaling pathway

their assistances in the experiments. Author Contributions Conceptualization: Jianguang Li, Jianguo Xing. Data curation: Cheng Zeng, Jianguang Li. Formal analysis: Cheng Zeng, Wen Jiang. Funding ... , Jianguo Xing. Investigation: Cheng Zeng, Wen Jiang, Ruifang Zheng, Chenghui He. 14 / 17 Writing ± original draft: Cheng Zeng, Jianguo Xing. Writing ± review & editing: Cheng Zeng, Jianguang Li, Jianguo

Mutagenesis and characterization of a Bacillus amyloliquefaciens strain for Cinnamomum camphora seed kernel oil extraction by aqueous enzymatic method

The purpose of the present study was to increase the proteinase activity of the strain NCU116 by combining ultraviolet irradiation and N-methyl-N′-nitro-N-nitroso guanidine treatment, in order to enhance the efficiency of Cinnamomum camphora seed kernel oil (CCSKO) extraction by aqueous enzymatic method (AEM). The mutated strain, designated as NCU116-1, was screened out by the...

Abnormal phase transition between two-dimensional high-density liquid crystal and low-density crystalline solid phases

Some two-dimensional liquid systems are theoretically predicted to have an anomalous phase transition due to unique intermolecular interactions, for example the first-order transition between two-dimensional high-density water and low-density amorphous ice. However, it has never been experimentally observed, to the best of our knowledge. Here we report an entropy-driven phase...

FOXP3 inhibits angiogenesis by downregulating VEGF in breast cancer

Forkhead box P3 (FOXP3), an X-linked tumor suppressor gene, plays an important role in breast cancer. However, the biological functions of FOXP3 in breast cancer angiogenesis remain unclear. Here we found that the clinical expression of nuclear FOXP3 was inversely correlated with breast cancer angiogenesis. Moreover, the animal study demonstrated that FOXP3 significantly reduced...

Nuclear galectin-1-FOXP3 interaction dampens the tumor-suppressive properties of FOXP3 in breast cancer

FOXP3 is an important X-linked suppressor of breast cancer. It is reported that FOXP3 is usually mutant, absent, or cytoplasmic distribution in breast cancer cells, which increases the risk of breast cancer. However, in our study the full-length FOXP3 transcript can be detected in breast cancer cells and nuclear FOXP3 is expressed in some breast cancer samples. Therefore, an...

Ion-specific ice recrystallization provides a facile approach for the fabrication of porous materials

. Francisco & Xiao Cheng ZengBeijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, ChinaChongqin Zhu & Xiao Cheng Zeng ... Research journals • PubMed • Google ScholarSearch for Joseph S. Francisco in:Nature Research journals • PubMed • Google ScholarSearch for Xiao Cheng Zeng in:Nature Research journals • PubMed • Google

Preliminary characterization of a novel β-agarase from Thalassospira profundimonas

Background The objective of this study was to characterize the agarase from a newly isolated agarolytic bacterium Thalassospira profundimaris fst-13007. Results Agarase-fst was purified to homogeneity which apparent molecular weight was 66.2 kDa. Its activity was optimal at 45 °C and pH 8 and was stable at pH 5–9 or 30–50 °C. Agarase-fst required Mn2+ for agarase activity and...

Development of solid lipid nanoparticles containing total flavonoid extract from Dracocephalum moldavica L. and their therapeutic effect against myocardial ischemia–reperfusion injury in rats

Tan,1–3,* Cheng-hui He,3,* Wen Jiang,4 Cheng Zeng,2–4 Ning Yu,3 Wei Huang,2 Zhong-gao Gao,2 Jian-guo Xing3 1Key Laboratory of Xinjiang Endemic Phytomedicine Resources of Ministry of Education, School of

A Biomechanical Stability Study of Extraforaminal Lumbar Interbody Fusion on the Cadaveric Lumbar Spine Specimens

Background Transforaminal lumbar interbody fusion (TLIF) is an effective surgery for lumbar degenerative disease. However, this fusion technique requires resection of inferior facet joint to provide access for superior facet joint resection, which results in reduced lumbar spinal stability and unnecessary trauma. We have previously developed extraforaminal lumbar interbody fusion...

Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

Ye,1 Chin-Hui Lai,1 Jun Luo,1 Xiaoying Huang,1 Wei Wang,1 Cheng Zeng,1 Zibiao Zhong,1 Xiaoli Fan,1 Zhiping Xia,1 Yan Xiong,1 Xinfang Mao,3 Qifa Ye,1,2 and Yanfeng Wang1 1Zhongnan Hospital of Wuhan

Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

Ye,1 Chin-Hui Lai,1 Jun Luo,1 Xiaoying Huang,1 Wei Wang,1 Cheng Zeng,1 Zibiao Zhong,1 Xiaoli Fan,1 Zhiping Xia,1 Yan Xiong,1 Xinfang Mao,3 Qifa Ye,1,2 and Yanfeng Wang1 1Zhongnan Hospital of Wuhan

Fabrication and Photoluminescence Study of Large-Area Ordered and Size-Controlled GeSi Multi-quantum-well Nanopillar Arrays

Zhichao Zhu Cheng Zeng Yongliang Fan 1 Zuimin Jiang 1 0 Equal contributors 1 State Key Laboratory of Surface Physics, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education

Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method

In this study, a sensitive, precise, and accurate HPLC-UV method was developed and validated to simultaneously determine the six analytes (luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, tilianin, and rosmarinic acid) in Yixin Badiranjibuya Granules, in which five analytes (i.e., luteolin-7-O-β-D-glucuronide...

Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method

In this study, a sensitive, precise, and accurate HPLC-UV method was developed and validated to simultaneously determine the six analytes (luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, tilianin, and rosmarinic acid) in Yixin Badiranjibuya Granules, in which five analytes (i.e., luteolin-7-O-β-D-glucuronide...

Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method

In this study, a sensitive, precise, and accurate HPLC-UV method was developed and validated to simultaneously determine the six analytes (luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, tilianin, and rosmarinic acid) in Yixin Badiranjibuya Granules, in which five analytes (i.e., luteolin-7-O-β-D-glucuronide...

miRNA-135a promotes hepatocellular carcinoma cell migration and invasion by targeting forkhead box O1

Zhang 6 JianY‑ing Huang 5 Lei Zhang 5 Xian‑Cheng Zeng 0 4 5 0 Department of General Surgery and Clinical Laboratory, Zengcheng People's Hospital (BoJi‐ Affiliated Hospital of Sun Yat‐ Sen University