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17 papers found.
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A Dual-Modality Hybrid Imaging System Harnesses Radioluminescence and Sound to Reveal Molecular Pathology of Atherosclerotic Plaques

, Stanford University School of Medicine, Stanford, USAZhen Qiu, Christopher H. Contag, Sanjiv S. Gambhir & Frederick T. ChinDepartment of Biomedical Engineering, Viterbi School of Engineering, University of ... Southern California, Stanford, USARuimin Chen & K. Kirk ShungMolecular Imaging Program at Stanford University (MIPS), Stanford University School of Medicine, Stanford, USARaiyan T. Zaman, Christopher H

Intracellular biomass flocculation as a key mechanism of rapid bacterial killing by cationic, amphipathic antimicrobial peptides and peptoids

• PubMed • Google Scholar Search for Christopher H. Contag in:Nature Research journals • PubMed • Google Scholar Search for Annelise E. Barron in:Nature Research journals • PubMed • Google Scholar

Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells

Pauline Chu Michael H. Bachmann 0 Nhat M. Hoang Deborah Collyar Aaron T. Mayer Robert B. West William J. Maloney Christopher H. Contag 0 Bonnie L. King 0 0 Department of Pediatrics, Stanford University

Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass

Superoxide anion is produced during normal cellular respiration and plays key roles in cellular physiology with its dysregulation being associated with a variety of diseases. Superoxide anion is a short-lived molecule and, therefore, its homeostatic regulation and role in biology and disease requires dynamic quantification with fine temporal resolution. Here we validated...

The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice

, William H. Robinson, Christopher H. Contag. Resources: Harini Raghu, Jeremy Sokolove, William H. Robinson, Christopher H. Contag. Supervision: Stephen J. Galli. Writing ± original draft: Laurent L. Reber ... Jeremy Sokolove, William H. Robinson, Christopher H. Contag, Mindy Tsai, Stephen J. Galli. 14 / 15 cancer. Clin Cancer Res. 2004; 10(10):3528±34. PMID

A Real-Time Clinical Endoscopic System for Intraluminal, Multiplexed Imaging of Surface-Enhanced Raman Scattering Nanoparticles

The detection of biomarker-targeting surface-enhanced Raman scattering (SERS) nanoparticles (NPs) in the human gastrointestinal tract has the potential to improve early cancer detection; however, a clinically relevant device with rapid Raman-imaging capability has not been described. Here we report the design and in vivo demonstration of a miniature, non-contact, opto-electro...

Development of B Cells and Erythrocytes Is Specifically Impaired by the Drug Celastrol in Mice

Background Celastrol, an active compound extracted from the root of the Chinese medicine “Thunder of God Vine” (Tripterygium wilfordii), exhibits anticancer, antioxidant and anti-inflammatory activities, and interest in the therapeutic potential of celastrol is increasing. However, described side effects following treatment are significant and require investigation prior to...

Heme Oxygenase-1 Deletion Affects Stress Erythropoiesis

. Stevenson 0 Christopher H. Contag 0 Steven R. Ellis, University of Louisville, United States of America 0 1 Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United

Role of nitric oxide in Salmonella typhimurium-mediated cancer cell killing

Yoram Barak 0 Frank Schreiber Steve H Thorne Christopher H Contag Dirk deBeer A Matin 0 0 Department of Microbiology and Immunology, Sherman Fairchild Science Building, Stanford University School of

Visualization of plasmid delivery to keratinocytes in mouse and human epidermis

University School of Medicine, CA, USAEmilio González-González, Ryan Spitler, Maria Fernanda Lara, Christopher H. Contag & Roger L. KasparDepartment of Radiology, Stanford University School of Medicine, CA ... journals • PubMed • Google ScholarSearch for Leonard M. Milstone in:Nature Research journals • PubMed • Google ScholarSearch for Christopher H. Contag in:Nature Research journals • PubMed • Google

Optical Monitoring and Treatment of Potentially Lethal Wound Infections In Vivo

We report on the use of optical techniques to monitor and treat Pseudomonas aeruginosa wound infections in mice. Bioluminescent bacteria transduced with a plasmid containing a bacterial lux gene operon allow the infection in excisional mouse wounds to be imaged by use of a sensitive charge-coupled device camera. Photodynamic therapy (PDT) targeted bacteria, by use of a...

Breast-Milk Shedding of Drug-Resistant HIV-1 Subtype C in Women Exposed to Single-Dose Nevirapine

Single-dose nevirapine reduces intrapartum human immunodeficiency virus 1 type (HIV-1) transmission but may also select for nonnucleoside reverse-transcriptase inhibitor (NNRTI) resistance in breast milk (BM) and plasma. Among 32 Zimbabwean women, median 8-week postpartum plasma and BM HIV-1 RNA levels were 4.57 and 2.13 log10 copies/mL, respectively. BM samples from women with...