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Exploration of potential risks of Hand, Foot, and Mouth Disease in Inner Mongolia Autonomous Region, China Using Geographically Weighted Regression Model

variance of the estimated parameters ?j(ui, vi) (i = 1, 2, ?, n) for a given j (1 ? j ? p + 1). Author Contributions In this study, Zhimin Hong, Hui Hao, Chunyang Li and Wala Du conceived, designed and ... Chunyang Li wrote the paper; Huhu Wang, Chunyang Li, Lidong Wei and Wala Du helped in data interpretation and manuscript preparation. All of the authors read and approved the final manuscript. Additional

Experimental Study on the Flow and Heat Transfer Characteristics of TiO2-Water Nanofluids in a Spirally Fluted Tube

The flow and heat transfer characteristics of TiO2-water nanofluids with different nanoparticle mass fractions in a spirally fluted tube and a smooth tube are experimentally investigated at different Reynolds numbers. The effects of pH values and doses of dispersant agent on the stability of TiO2-water nanofluids are discussed. The effects of nanoparticle mass fractions and...

Optimization Design of IGV Profile in Centrifugal Compressor

Variable inlet guide vane (IGV) is used to control the mass flow and generate prewhirl in centrifugal compressors. The efficient operation of IGV is limited to the range of aerodynamic characteristics of their vane profiles. In order to find out the best vane profile for IGV regulation, the modern optimization method was adopted to optimize the inlet guide vane profile. The main...

Markov Chain-Based Acute Effect Estimation of Air Pollution on Elder Asthma Hospitalization

it critically for important intellectual content. Lin Sun, Chunyang Li, Huang Debin, Han Gao, and Bin Wang have involved in the conception and design of this research. All authors read and approved the

Markov Chain-Based Acute Effect Estimation of Air Pollution on Elder Asthma Hospitalization

it critically for important intellectual content. Lin Sun, Chunyang Li, Huang Debin, Han Gao, and Bin Wang have involved in the conception and design of this research. All authors read and approved the

Novel microduplication of CHL1 gene in a patient with autism spectrum disorder: a case report and a brief literature review

Background The cell adhesion molecule L1-like (CHL1 or CALL) gene is located on chromosome 3p26.3, and it is highly expressed in the central and peripheral nervous systems. The protein encoded by this gene is a member of the L1 family of neural cell adhesion molecules, and it plays a role in nervous system development and synaptic plasticity. Moreover, studies of mice have...

Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Properties in Endothelial Cells

The objective of this research was to survey the antioxidant functional role of the main anthocyanins of blueberries in endothelial cells. Changes on the reactive oxygen species (ROS), xanthine oxidase-1 (XO-1), superoxide dismutase (SOD), and heme oxygenase-1 (HO-1) in cells of malvidin and the two glycosides were investigated. The results showed that these anthocyanins...

Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Properties in Endothelial Cells

The objective of this research was to survey the antioxidant functional role of the main anthocyanins of blueberries in endothelial cells. Changes on the reactive oxygen species (ROS), xanthine oxidase-1 (XO-1), superoxide dismutase (SOD), and heme oxygenase-1 (HO-1) in cells of malvidin and the two glycosides were investigated. The results showed that these anthocyanins...

A lithium ion battery using an aqueous electrolyte solution

Energy and environmental pollution have become the two major problems in today’s society. The development of green energy storage devices with good safety, high reliability, high energy density and low cost are urgently demanded. Here we report on a lithium ion battery using an aqueous electrolyte solution. It is built up by using graphite coated with gel polymer membrane and...

Human Umbilical Cord Mesenchymal Stem Cells and Derived Hepatocyte-Like Cells Exhibit Similar Therapeutic Effects on an Acute Liver Failure Mouse Model

Mesenchymal stem cells (MSCs) have exhibited therapeutic effects in multiple animal models so that are promising liver substitute for transplantation treatment of end-stage liver diseases. However, it has been shown that over-manipulation of these cells increased their tumorigenic potential, and that reducing the in vitro culture time could minimize the risk. In this study, we...

A Facile Synthesis and Optical Properties of Bundle-Shaped TbPO4·H2O Nanorods

Bundle-shaped TbPO4·H2O nanorods have been prepared by a facile hydrothermal technique and characterized by XRD, SEM, TEM, UV-Vis diffuse reflectance spectrum (DRS), photoluminescence (PL) spectrum, and lifetime. The results indicate that the obtained sample has hexagonal structure of TbPO4·H2O and is composed of nanorods bundles which is assembled from many single crystalline...

A Facile Synthesis and Optical Properties of Bundle-Shaped TbPO4·H2O Nanorods

Bundle-shaped TbPO4·H2O nanorods have been prepared by a facile hydrothermal technique and characterized by XRD, SEM, TEM, UV-Vis diffuse reflectance spectrum (DRS), photoluminescence (PL) spectrum, and lifetime. The results indicate that the obtained sample has hexagonal structure of TbPO4·H2O and is composed of nanorods bundles which is assembled from many single crystalline...

The Immune Adaptor ADAP Regulates Reciprocal TGF-β1-Integrin Crosstalk to Protect from Influenza Virus Infection

Highly pathogenic avian influenza virus (HPAI, such as H5N1) infection causes severe cytokine storm and fatal respiratory immunopathogenesis in human and animal. Although TGF-β1 and the integrin CD103 in CD8+ T cells play protective roles in H5N1 virus infection, it is not fully understood which key signaling proteins control the TGF-β1-integrin crosstalk in CD8+ T cells to...

Molecular Switch Role of Akt in Polygonatum odoratum Lectin-Induced Apoptosis and Autophagy in Human Non-Small Cell Lung Cancer A549 Cells

Polygonatum odoratum lectin (POL), isolated from traditional Chinese medicine herb (Mill.) Druce, has drawn rising attention due to its wide biological activities. In the present study, anti-tumor effects, including apoptosis- and autophagy-inducing properties of POL, were determined by a series of cell biology methods such as MTT, cellular morphology observation, flow cytometry...

Transcriptional profiling analysis in Populus yunnanensis provides insights into molecular mechanisms of sexual differences in salinity tolerance

Physiological responses to abiotic stress in plants exhibit sexual differences. Females usually experience greater negative effects than males; however, little is known about the molecular mechanisms of sexual differences in abiotic stress responses. In the present study, transcriptional responses to salinity treatments were compared between male and female individuals of the...

Nitrogen nutrient status induces sexual differences in responses to cadmium in Populus yunnanensis

Populus yunnanensis was employed as a model species to detect sexual differences in growth, physiological, biochemical, and ultrastructural responses to cadmium (Cd) stress, nitrogen (N) deposition, and their combination. Compared with the control conditions, Cd decreased plant biomass, damaged the photosynthetic apparatus, visible as a decreased maximum efficiency of photosystem...

Expressed sequence tags analysis revealing the taxonomic position and fatty acid biosynthesis in an oleaginous green microalga, Myrmecia incisa Reisigl (Trebouxiophyceae, Chlorophyta)

cDNA library of Myrmecia incisa H4301 was constructed using λ phage vectors. The library consisted of 1.5×106 clones with a recombination rate of 90%, and 1942 clones were randomly sequenced. All 1854 readable expressed sequence tags (ESTs) were clustered into 596 non-redundant sequences (NRSs), among which 126 NRSs were from 1384 ESTs, showing a high redundancy. Among the 596...

Sex-related differences in morphological, physiological, and ultrastructural responses of Populus cathayana to chilling

Low temperature is one of the abiotic factors limiting plant growth and productivity. Yet, knowledge about sex-related responses to low temperature is very limited. In our study, the effects of low, non-freezing temperature on morphological, physiological, and ultrastructural traits of leaves in Populus cathayana Rehd. males and females were investigated. The results showed that...