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Search: authors:"Coreen M. Beaumier"

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Invited Commentary on Genetically Modified Mosquitoes for Population Control of Pathogen-Transmitting Wild-Type Mosquitoes

0 Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine , Houston, TX , USA 1 Coreen M. Beaumier

Cross-Reactive Memory CD8+ T Cells Alter the Immune Response to Heterologous Secondary Dengue Virus Infections in Mice in a Sequence-Specific Manner

Dengue virus is the causative agent of dengue fever and the more-severe dengue hemorrhagic fever (DHF). Human studies suggest that the increased risk of DHF during secondary infection is due to immunopathology partially mediated by cross-reactive memory T cells from the primary infection. To model T cell responses to sequential infections, we immunized mice with different...