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Search: authors:"Cynthia Besch-Williford"

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Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells

Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells Matthew T Cook,1,2 Yayun Liang,1,2 Cynthia Besch-Williford,3 Salman M Hyder1,2 1Department of

Luteolin inhibits progestin-dependent angiogenesis, stem cell-like characteristics, and growth of human breast cancer xenografts

PurposeClinical trials and epidemiological evidence have shown that combined estrogen/progestin hormone replacement therapy, but not estrogen therapy alone, increases breast cancer risk in post-menopausal women. Previously we have shown that natural and synthetic progestins, including the widely used synthetic progestin medroxyprogesterone acetate (MPA), increase production of a...

Apigenin Induces Apoptosis and Blocks Growth of Medroxyprogesterone Acetate-Dependent BT-474 Xenograft Tumors

Recent clinical and epidemiological evidence shows that hormone replacement therapy (HRT) containing both estrogen and progestin increases the risk of primary and metastatic breast cancer in post-menopausal women while HRT containing only estrogen does not. We and others previously showed that progestins promote the growth of human breast cancer cells in vitro and in vivo. In...

The Xpc gene markedly affects cell survival in mouse bone marrow

Joshua L. Fischer M.A. Suresh Kumar Travis W. Day Tabitha M. Hardy Shari Hamilton Cynthia Besch- Williford Ahmad R. Safa Karen E. Pollok Martin L. Smith - The XPC protein (encoded by the xeroderma