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Numerical calculation of boundary layers and wake characteristics of high-speed trains with different lengths

with a train's increasing length. The same trend occurs in the drag coefficient of the tail car. Author Contributions Conceptualization: Dan Zhou, Jiqiang Niu. Data curation: Lirong Jia. Formal ... analysis: Lirong Jia. Investigation: Lirong Jia, Jiqiang Niu. Methodology: Jiqiang Niu. Project administration: Dan Zhou. Software: Dan Zhou. Supervision: Dan Zhou. Validation: Lirong Jia

Synthesis of 3D Hexagram-Like Cobalt–Manganese Sulfides Nanosheets Grown on Nickel Foam: A Bifunctional Electrocatalyst for Overall Water Splitting

The exploration of low-cost and efficient bifunctional electrocatalysts for oxygen evolution reaction and hydrogen evolution reaction through tuning the chemical composition is strongly required for sustainable resources. Herein, we developed a bimetallic cobalt–manganese sulfide supported on Ni foam (CMS/Ni) via a solvothermal method. It has discovered that after combining with...

2-aminopurine suppresses the TGF-β1-induced epithelial–mesenchymal transition and attenuates bleomycin-induced pulmonary fibrosis

Hospital, Tongji University School of Medicine, Shanghai, ChinaDong Weng, Jian-xia Chen, Li-dan Zhou, Hai-peng Liu, Yan Jiang & Baoxue GeShanghai TB Key Labotatory, Shanghai Pulmonary Hospital, Tongji ... for Hao-hao Li in:Nature Research journals • PubMed • Google Scholar Search for Feng Liu in:Nature Research journals • PubMed • Google Scholar Search for Li-dan Zhou in:Nature Research journals

PCDH18 is frequently inactivated by promoter methylation in colorectal cancer

science and technology project for the benefit of the people (Grant No. 3502Z20164010). Author information Author notes Dan Zhou and Weiwei Tang contributed equally to this work. AffiliationsKey ... Affiliated Hospital of Xiamen University, Xiamen, Fujian, ChinaGuoqiang Su AuthorsSearch for Dan Zhou in:Nature Research journals • PubMed • Google Scholar Search for Weiwei Tang in:Nature Research journals

Moving Model Test of High-Speed Train Aerodynamic Drag Based on Stagnation Pressure Measurements

A moving model test method based on stagnation pressure measurements is proposed to measure the train aerodynamic drag coefficient. Because the front tip of a high-speed train has a high pressure area and because a stagnation point occurs in the center of this region, the pressure of the stagnation point is equal to the dynamic pressure of the sensor tube based on the obtained...

Monitoring changes of docosahexaenoic acid-containing lipids during the recovery process of traumatic brain injury in rat using mass spectrometry imaging

Brain lipid homoeostasis is critical during recovery process after traumatic brain injury (TBI). In this study, we integrated liquid extraction and electrosonic spray ionization technology to develop an ionization device coupled with a Fourier transform ion cyclotron resonance mass spectrometer for imaging of docosahexaenoic acid (DHA)-containing lipids on rat brain tissues. The...

Searching for hidden-charm baryonium signals in QCD sum rules

We give an explicit QCD sum rule investigation for hidden-charm baryonium states with the quark content \(u\bar{u} d\bar{d} c\bar{c}\), spin \(J=0/1/2/3\), and of both positive and negative parities. We systematically construct the relevant local hidden-charm baryonium interpolating currents, which can actually couple to various structures, including hidden-charm baryonium states...

Determination of Heavy Metals in Alpinia oxyphylla Miq. Collected from Different Cultivation Regions

2016 Academic Editor: Miren Lopez de Alda Copyright © 2016 Dan Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use ... Miq. Competing Interests The authors declare that they have no competing interests. Authors’ Contributions Dan Zhou and Yurong Fu are equal contributors. Acknowledgments The authors wish to express

High-Performance Flexible Asymmetric Supercapacitor Based on CoAl-LDH and rGO Electrodes

A flexible asymmetric supercapacitor (ASC) based on a CoAl-layered double hydroxide (CoAl-LDH) electrode and a reduced graphene oxide (rGO) electrode was successfully fabricated. The CoAl-LDH electrode as a positive electrode was synthesized by directly growing CoAl-LDH nanosheet arrays on a carbon cloth (CC) through a facile hydrothermal method, and it delivered a specific...

Nrf2, a Potential Therapeutic Target against Oxidative Stress in Corneal Diseases

/suppressor and corneal diseases. Disclosure Xiu-Fen Liu and Dan-Dan Zhou are co-first authors. Conflicts of Interest The authors declare that they have no conflicts of interest. Acknowledgments This study was

Evolution of crystal and electronic structures of magnesium dicarbide at high pressure

10000, ChinaYanhui Liu AuthorsSearch for Dashuai Wang in:Nature Research journals • PubMed • Google ScholarSearch for Yan Yan in:Nature Research journals • PubMed • Google ScholarSearch for Dan Zhou ... to the paper. Competing interests The authors declare no competing financial interests. Corresponding authors Correspondence to Dan Zhou or Yanhui Liu. Rights and permissions This work is licensed

Modeling Mixed Bicycle Traffic Flow: A Comparative Study on the Cellular Automata Approach

University, Hangzhou 310058, China Received 10 December 2014; Revised 29 April 2015; Accepted 30 April 2015 Academic Editor: Tetsuji Tokihiro Copyright © 2015 Dan Zhou et al. This is an open access

Genomic Analysis of Detoxification Supergene Families in the Mosquito Anopheles sinensis

Anopheles sinensis is an important malaria vector in China and other Southeast Asian countries, and the emergence of insecticide resistance in this mosquito poses a serious threat to the efficacy of malaria control programs. The recently published An. sinensis genome and transcriptome provide an opportunity to understand the molecular mechanisms of insecticide resistance...

Network Analysis of Functional Brain Connectivity Driven by Gamma-Band Auditory Steady-State Response in Auditory Hallucinations

The auditory steady-state response (ASSR) may reflect activity from different regions of the brain. Particularly, it was reported that the gamma-band ASSR plays an important role in working memory, speech understanding, and recognition. Traditionally, the ASSR has been determined by power spectral density analysis, which cannot detect the exact overall distributed properties of...

Anti-Arthritic Effect of Chebulanin on Collagen-Induced Arthritis in Mice

Rheumatoid arthritis is a chronic degenerative autoimmune disease characterized by persistent inflammation of synovial membranes, which leads to cartilage destruction and bone erosion. To date, there are no effective therapies to slow the progress of this degenerative condition. Here, we evaluate the anti-arthritic effect of chebulanin, an abundant anti-inflammatory agent...

Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations

The ability to withstand low oxygen (hypoxia tolerance) is a polygenic and mechanistically conserved trait that has important implications for both human health and evolution. However, little is known about the diversity of genetic mechanisms involved in hypoxia adaptation in evolving populations. We used experimental evolution and whole-genome sequencing in Drosophila...

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway

the manuscript; Dan ZHOU, Wei ZHOU, Jun-ke SONG, Zhang-ying FENG, and Ran-yao YANG performed the experiments; Jun-ke SONG helped to edit several figures and analyse data; Song WU and Lin WANG supplied ... the DL0410 compound; Dan ZHOU and Wei ZHOU analyzed the data. References 1. Alzheimer's Association. 2012 Alzheimer's disease facts and figures. Alzheimers Dement 2012; 8: 131–68

Experimental evolution of recombination and crossover interference in Drosophila caused by directional selection for stress-related traits

Background Population genetics predicts that tight linkage between new and/or pre-existing beneficial and deleterious alleles should decrease the efficiency of natural selection in finite populations. By decoupling beneficial and deleterious alleles and facilitating the combination of beneficial alleles, recombination accelerates the formation of high-fitness genotypes. This may...

A novel variant on chromosome 6p21.1 is associated with the risk of developing colorectal cancer: a two-stage case-control study in Han Chinese

Background Genes in inflammatory pathways play a pivotal role in the development of colorectal cancer. We conducted a two-stage case-control study and aimed at screening the colorectal cancer-associated genetic variations in inflammatory genes. Methods Twenty-three candidate variants were genotyped in 952 primary colorectal cancer cases and 875 cancer-free controls from eastern...