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Process evaluation of the school-based Girls Active programme

GorelyUniversity of Leicester, Diabetes Research Centre, Leicester General Hospital, Leicester, LE5 4PW, UKDeirdre M. Harrington, Danielle H. Bodicoat, Melanie J. Davies, Kamlesh Khunti, Thomas Yates & Charlotte L ... -Edwards AuthorsSearch for Trish Gorely in:PubMed • Google Scholar Search for Deirdre M. Harrington in:PubMed • Google Scholar Search for Danielle H. Bodicoat in:PubMed • Google Scholar Search for Melanie

Micro-costing and a cost-consequence analysis of the ‘Girls Active’ programme: A cluster randomised controlled trial

, Melanie J. Davies, Charlotte L. Edwardson, Trish Gorely, Danielle H. Bodicoat, Kamlesh Khunti, Lauren B. Sherar, Thomas Yates, Rhiannon Tudor Edwards. Formal analysis: Joanna M. Charles. Funding ... acquisition: Melanie J. Davies. Investigation: Joanna M. Charles. Methodology: Joanna M. Charles, Deirdre M. Harrington, Melanie J. Davies, Charlotte L. Edwardson, Trish Gorely, Danielle H. Bodicoat, Kamlesh

Differences in objectively measured physical activity and sedentary behaviour between white Europeans and south Asians recruited from primary care: cross-sectional analysis of the PROPELS trial

Self-reported data have consistently shown South Asians (SAs) to be less physically active than White Europeans (WEs) in developed countries, however objective data is lacking. Differences in sedentary time have not been elucidated in this population. This study aimed to quantify differences in objectively measured physical activity and sedentary behaviour between WEs and SAs...

Effectiveness of the ‘Girls Active’ school-based physical activity programme: A cluster randomised controlled trial

Globally, adolescent girls’ physical activity (PA) levels are low. The ‘Girls Active’ secondary school-based programme, developed by the Youth Sport Trust, aims to increase PA in adolescent girls. This paper explores the effectiveness of the ‘Girls Active’ school-based PA programme. A random sample of girls aged 11–14 from 20 secondary schools (Midlands, UK) participated in a two...

The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis

Aims To determine the effects of glucagon-like peptide-1 receptor agonists compared with placebo and other anti-diabetic agents on weight loss in overweight or obese patients with type 2 diabetes mellitus. Methods Electronic searches were conducted for randomised controlled trials that compared a glucagon-like peptide-1 receptor agonist therapy at a clinically relevant dose with...

Energy expenditure during common sitting and standing tasks: examining the 1.5 MET definition of sedentary behaviour

Background Sedentary behavior is defined as any waking behavior characterized by an energy expenditure of 1.5 METS or less while in a sitting or reclining posture. This study examines this definition by assessing the energy cost (METs) of common sitting, standing and walking tasks. Methods Fifty one adults spent 10 min during each activity in a variety of sitting tasks (watching...

Serum Potassium and Glucose Regulation in the ADDITION-Leicester Screening Study

of the core clinical team running the study. Patrice Carter, Melanie J. Davies, and Lauren M. Quinn developed the potassium analysis protocol. Danielle H. Bodicoat conducted all statistical analyses ... . Patrice Carter and Danielle H. Bodicoat wrote the initial paper; Melanie J. Davies, Kamlesh Khunti, David Webb, Francesco Zaccardi, and Lauren M. Quinn contributed to the final paper. Acknowledgments The

Serum Potassium and Glucose Regulation in the ADDITION-Leicester Screening Study

Research Council. Patrice Carter, Danielle H. Bodicoat, Francesco Zaccardi, and Lauren M. Quinn have nothing to declare. Authors’ Contribution Melanie J. Davies (Principle investigator) and Kamlesh Khunti ... . Bodicoat conducted all statistical analyses. Patrice Carter and Danielle H. Bodicoat wrote the initial paper; Melanie J. Davies, Kamlesh Khunti, David Webb, Francesco Zaccardi, and Lauren M. Quinn

Prevalence and Incidence of Hypoglycaemia in 532,542 People with Type 2 Diabetes on Oral Therapies and Insulin: A Systematic Review and Meta-Analysis of Population Based Studies

Objective To collate and evaluate the current literature reporting the prevalence and incidence of hypoglycaemia in population based studies of type 2 diabetes. Research Design and Methods Medline, Embase and Cochrane were searched up to February 2014 to identify population based studies reporting the proportion of people with type 2 diabetes experiencing hypoglycaemia or rate of...

Breaking Up Prolonged Sitting With Standing or Walking Attenuates the Postprandial Metabolic Response in Postmenopausal Women: A Randomized Acute Study

OBJECTIVE To determine whether breaking up prolonged sitting with short bouts of standing or walking improves postprandial markers of cardiometabolic health in women at high risk of type 2 diabetes.

A Randomised Controlled Trial to Reduce Sedentary Time in Young Adults at Risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time ANd Diabetes)

Aims Type 2 diabetes mellitus (T2DM), a serious and prevalent chronic disease, is traditionally associated with older age. However, due to the rising rates of obesity and sedentary lifestyles, it is increasingly being diagnosed in the younger population. Sedentary (sitting) behaviour has been shown to be associated with greater risk of cardio-metabolic health outcomes, including...

Evaluation of a tailored intervention to improve management of overweight and obesity in primary care: study protocol of a cluster randomised controlled trial

Background In the UK around 22% of men and 24% of women are obese, and there are varying but worrying levels in other European countries. Obesity is a chronic condition that carries an important health risk. National guidelines, for use in England, on the management of people who are overweight or obese have been published by the National Institute for Health and Clinical...

Diabetes Prevention in the Real World: Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes and of the Impact of Adherence to Guideline Recommendations: A Systematic Review and Meta-analysis

A Systematic Review Meta-analysis Alison J. Dunkley Danielle H. Bodicoat Colin J. Greaves Claire Russell Thomas Yates Melanie J. Davies Kamlesh Khunti To summarize the evidence on effectiveness of

Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study

Introduction Breast development and hormonal changes at puberty might affect breast cancer risk, but epidemiological analyses have focussed largely on age at menarche and not at other pubertal stages. Methods We investigated associations between the timing of pubertal stages and breast cancer risk using data from a cohort study of 104,931 women (Breakthrough Generations Study, UK...

Effect of the PPARG2 Pro12Ala Polymorphism on Associations of Physical Activity and Sedentary Time with Markers of Insulin Sensitivity in Those with an Elevated Risk of Type 2 Diabetes

Background Peroxisome proliferator-activated receptor gamma (PPARγ) is an important regulator of metabolic health and a common polymorphism in the PPAR-γ2 gene (PPARG2) may modify associations between lifestyle behaviour and health. Objective To investigate whether the PPARG2 Pro12Ala genotype modifies the associations of sedentary behaviour and moderate-to-vigorous intensity...

PRomotion Of Physical activity through structured Education with differing Levels of ongoing Support for people at high risk of type 2 diabetes (PROPELS): study protocol for a randomized controlled trial

Background The prevention of type 2 diabetes is recognised as a health care priority. Lifestyle change has proven effective at reducing the risk of type 2 diabetes, but limitations in the current evidence have been identified in: the promotion of physical activity; availability of interventions that are suitable for commissioning and implementation; availability of evidence-based...

Body Mass Index and Waist Circumference Cut-Points in Multi-Ethnic Populations from the UK and India: The ADDITION-Leicester, Jaipur Heart Watch and New Delhi Cross-Sectional Studies

Aims To derive cut-points for body mass index (BMI) and waist circumference (WC) for minority ethnic groups that are risk equivalent based on endogenous glucose levels to cut-points for white Europeans (BMI 30 kg/m2; WC men 102 cm; WC women 88 cm). Materials and Methods Cross-sectional data from participants aged 40–75 years: 4,672 white and 1,348 migrant South Asian participants...