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Autologous stem cell therapy for peripheral arterial disease: a systematic review and meta-analysis of randomized controlled trials

BackgroundPeripheral arterial disease (PAD) is a common cause of disability and mortality. The reconstruction of blood circulation presents to be the key to treatment, which can be achieved by surgery and interventional therapy. Since 40% patients have lost the chance for the therapy, a new method is needed to reduce the amputation and mortality rate for “no-option” patients. The...

Integrated coordination scheduling framework of electricity-natural gas systems considering electricity transmission N − 1 contingencies and gas dynamics

This paper discusses a security-constrained integrated coordination scheduling framework for an integrated electricity-natural gas system (IEGS), in which both tight interdependence between electricity and natural gas transmission networks and their distinct dynamic characteristics at different timescales are fully considered. The proposed framework includes two linear...

Total lymphocyte count, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio as prognostic factors in advanced non–small cell lung cancer with chemoradiotherapy

Total lymphocyte count, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio as prognostic factors in advanced non–small cell lung cancer with chemoradiotherapy Xinyu Song,1,2,* Dawei Chen,3 ... : Dr Ahmet Emre Eskazan Xinyu Song,1,2,* Dawei Chen,3,* Ma Yuan,4 Haiyong Wang,1 Zhehai Wang1 1Department of Medical Oncology, Shandong Cancer Hospital Affiliated to Shandong University

A novel disulfide bond-mediated cleavable RGD-modified PAMAM nanocomplex containing nuclear localization signal HMGB1 for enhancing gene transfection efficiency

, Ming Zhao, Haiyang Hu, Dawei Chen Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China Background: Polyamidoamine (PAMAM) dendrimers modified by

Calibration Method to Eliminate Zeroth Order Effect in Lateral Shearing Interferometry

In this paper, a calibration method is proposed which eliminates the zeroth order effect in lateral shearing interferometry. An analytical expression of the calibration error function is deduced, and the relationship between the phase-restoration error and calibration error is established. The analytical results show that the phase-restoration error introduced by the calibration...

Screening differential circular RNA expression profiles reveal that hsa_circ_0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma

Screening differential circular RNA expression profiles reveal that hsa-circ-0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma Dawei Chen,1,2,* Chenyue Zhang,3

Hepatocellular carcinoma-targeted effect of configurations and groups of glycyrrhetinic acid by evaluation of its derivative-modified liposomes

Hepatocellular carcinoma-targeted effect of configurations and groups of glycyrrhetinic acid by evaluation of its derivative-modified liposomes Yuqi Sun,1,2 Chunmei Dai,1 Meilin Yin,1 Jinghua Lu,1 Haiyang Hu,2 Dawei Chen2 1School of Pharmacy, Jinzhou Medical University, Jinzhou, China; 2School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China Background: There are...

The Validity and Reliability between Automated Oscillometric Measurement of Ankle-Brachial Index and Standard Measurement by Eco-Doppler in Diabetic Patients with or without Diabetic Foot

 Min Liu,1 Dawei Chen,1 Chun Wang,1 Guanjian Liu,2 and Xingwu Ran1 1Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China

Multi-Objective Aerodynamic Optimization of the Streamlined Shape of High-Speed Trains Based on the Kriging Model

Minimizing the aerodynamic drag and the lift of the train coach remains a key issue for high-speed trains. With the development of computing technology and computational fluid dynamics (CFD) in the engineering field, CFD has been successfully applied to the design process of high-speed trains. However, developing a new streamlined shape for high-speed trains with excellent...

Effects of dipeptidyl peptidase-4 inhibitors on beta-cell function and insulin resistance in type 2 diabetes: meta-analysis of randomized controlled trials

supported by Merck & Co., Inc. Author information AffiliationsDiabetic Foot Care Center, West China Hospital, Sichuan University, Guoxue Lane No. 37, Chengdu, Sichuan, ChinaXiafei Lyu, Dawei Chen, Chun ... in:Nature Research journals • PubMed • Google ScholarSearch for Dawei Chen in:Nature Research journals • PubMed • Google ScholarSearch for Chun Wang in:Nature Research journals • PubMed • Google ScholarSearch

Population pharmacokinetics of peginterferon α2a in patients with chronic hepatitis B

REPoRtS | Population pharmacokinetics of peginterferon ?2a in patients with chronic hepatitis B Jingfeng Bi Xingang Li Jia Liu Dawei Chen Shuo Li Jun Hou Yuxia Zhou Shanwei Zhu Zhigang Zhao Enqiang

Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin

, Nanjing c hia Tai Tianqing Pharmaceutical group co. ltd , Nanjing 2 Dawei chen Department of Pharmaceutics, school of Pharmacy, shenyang Pharmaceutical University , 103 Wenhua road, shenyang 110016

The Effect of Autologous Platelet-Rich Gel on the Dynamic Changes of the Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 Expression in the Diabetic Chronic Refractory Cutaneous Ulcers

Ulcers Lan Li,1 Dawei Chen,1 Chun Wang,1 Guanjian Liu,2 and Xingwu Ran1 1Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041 ... Dawei Chen contributed equally to this work. The authors thank the Charge Nurse Min Liu (Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University) for

The Effect of Autologous Platelet-Rich Gel on the Dynamic Changes of the Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 Expression in the Diabetic Chronic Refractory Cutaneous Ulcers

Ulcers Lan Li,1 Dawei Chen,1 Chun Wang,1 Guanjian Liu,2 and Xingwu Ran1 1Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041 ... Dawei Chen contributed equally to this work. The authors thank the Charge Nurse Min Liu (Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University) for

The Effect of Autologous Platelet-Rich Gel on the Dynamic Changes of the Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 Expression in the Diabetic Chronic Refractory Cutaneous Ulcers

Ulcers Lan Li,1 Dawei Chen,1 Chun Wang,1 Guanjian Liu,2 and Xingwu Ran1 1Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041 ... Dawei Chen contributed equally to this work. The authors thank the Charge Nurse Min Liu (Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University) for

Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review

Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review Dawei Chen,1,2,* Yan Zhang,2,* Fang Shi,2

Oxytocin evokes a pulsatile PGE2 release from ileum mucosa and is required for repair of intestinal epithelium after injury

, Jinan, 250012, People’s Republic of ChinaDawei Chen, Junhan Zhao, Haoyi Wang, Ning An, Yuping Zhou, Jiahui Fan, Junwen Luo, Wenlong Su, Chuanyong Liu & Jingxin Li AuthorsSearch for Dawei Chen in:Nature

Identification of a Novel Protein Complex Containing ASIC1a and GABAA Receptors and Their Interregulation

Acid-sensing ion channels (ASICs) belong to the family of the epithelial sodium channel/degenerin (ENaC/DEG) and are activated by extracellular protons. They are widely distributed within both the central and peripheral nervous systems. ASICs were modified by the activation of γ-aminobutyric acid receptors (GABAA), a ligand-gated chloride channels, in hippocampal neurons. In...

Single peptide ligand-functionalized uniform hollow mesoporous silica nanoparticles achieving dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells

Ming Xu,3 Guannan Guan,1 Wen Hu,3 Ying Liang,2 Xiuli Zhao,1 Mingxi Qiao,1 Dawei Chen,1 Hao Liu2 1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Department of Pharmacy, Bengbu Medical

Novel Single Nucleotide Polymorphisms in Interleukin 6 Affect Tacrolimus Metabolism in Liver Transplant Patients

Background Tacrolimus is the first-line immunosuppressant after organ transplantation. It is mainly metabolized by cytochrome P450, family 3, subfamily A (CYP3A) enzymes, but there are large individual differences in metabolism. Interleukin 6 (IL6) has been shown to cause a pan-suppression of mRNA levels of ten major CYP enzymes in human hepatocyte cultures. IL6 has been shown to...